LASIRIDE 40MG/5MG TABLET is a combination of two medicines used to reduce excess fluid levels in the body. It is used to treat edema (fluid overload) and some cases of hypertension (high blood pressure). It is best to take LASIRIDE 40MG/5MG TABLET in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Nausea, vomiting, and diarrhea, dizziness or muscle weakness are some common side effects of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It is generally safe to use during pregnancy or breastfeeding. Before taking this medicine, tell your doctor if you have any liver or kidney disease. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 31-05-2025
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LASIRIDE 40MG/5MG TABLET is a combination of two medicines used to reduce excess fluid levels in the body. It is used to treat edema (fluid overload) and some cases of hypertension (high blood pressure). It is best to take LASIRIDE 40MG/5MG TABLET in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Nausea, vomiting, and diarrhea, dizziness or muscle weakness are some common side effects of this medicine. It might lower down the level of calcium, sodium, and magnesium in the blood. Hence, regular monitoring of kidney function and electrolytes is important while using this medicine. It is generally safe to use during pregnancy or breastfeeding. Before taking this medicine, tell your doctor if you have any liver or kidney disease. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Treatment of Edema
In Treatment of Edema Edema is caused by your body retaining too much water. LASIRIDE 40MG/5MG TABLET helps get rid of the extra water and electrolytes from your body by increasing the amount of urine produced. This enables your body to get rid of extra water thereby relieving symptoms such as shortness of breath and swelling in your arms, legs or abdomen. Therefore, you can carry out your daily activities more comfortably. Take it regularly and make appropriate lifestyle changes to get maximum benefits.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Vomiting, Diarrhea, Weakness, Headache, Dehydration, Muscle cramp, Decreased sodium level in blood, Decreased magnesium level in blood, Decreased calcium level in blood, Increased blood uric acid']
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. LASIRIDE 40MG/5MG TABLET is to be taken with food. Avoid LASIRIDE 40MG/5MG TABLET with dietary sodium.
LASIRIDE 40MG/5MG TABLET is a combination of two medicines: Furosemide and Amiloride. They act on different parts of your kidney to remove extra water and certain electrolytes while maintaining the potassium balance in your body.
Alcohol
Unsafe: Avoid consuming alcohol with LASIRIDE 40MG/5MG TABLET as it is deemed unsafe.
Pregnancy
Seek medical advice from your doctor: LASIRIDE 40MG/5MG TABLET may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Safe when prescribed by an expert: LASIRIDE 40MG/5MG TABLET is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
Not Safe: LASIRIDE 40MG/5MG TABLET may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
Caution Advised: LASIRIDE 40MG/5MG TABLET should be used with caution in patients with kidney disease. Dose adjustment of LASIRIDE 40MG/5MG TABLET may be needed. Doctor consultation is advised. Use of LASIRIDE 40MG/5MG TABLET is not recommended in patients with severe kidney disease.
Liver
Caution Advised: LASIRIDE 40MG/5MG TABLET should be used with caution in patients with liver disease. Dose adjustment of LASIRIDE 40MG/5MG TABLET may be needed. Doctor consultation is advised.
If a dose of LASIRIDE 40MG/5MG TABLET is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
LASIRIDE 40MG/5MG TABLET helps removes excess water from your body. Take it in the morning with breakfast to avoid getting up at night to urinate. It�may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. It may cause excessive urine production, dehydration, and low electrolyte levels. Notify your doctor if you experience dizziness, tiredness, or muscle weakness that doesn't go away. Your doctor may regularly monitor your blood pressure, kidney function and the level of salts such as potassium and sodium in your blood while you're taking this medication.
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