Ifyclin 20mg Tablet 10s

Ifyclin 20mg Tablet 10s is a modern oral medication belonging to the dihydropyridine class of Calcium Channel Blockers (CCBs). It is used primarily for the treatment of essential hypertension (high blood pressure). Ifyclin 20mg Tablet 10s possesses a unique mechanism: it blocks both L-type calcium channels (responsible for vessel constriction) and N-type calcium channels (which modulate sympathetic nerve activity). This dual action provides effective and sustained blood pressure control while offering potential advantages, such as a lower risk of reflex heart rate increase and minimised peripheral swelling, compared to conventional CCBs

Ifyclin 20mg Tablet 10s (Cilnidipine 10mg) is a medicine used to help control high blood pressure. High blood pressure, also called hypertension, can put extra strain on your heart, blood vessels, and kidneys. Lowering blood pressure reduces the risk of serious health problems such as stroke, heart attack, and kidney damage.

This medicine has a distinctive mode of action compared with many other treatments for high blood pressure. It targets two different types of calcium channels in the body. The L-type regulates the contraction of blood vessels, while the N-type influences the nerve signals that can increase blood pressure. By simultaneously blocking both pathways, Ifyclin 20mg Tablet 10s promotes relaxation of the blood vessels and reduces excessive nerve activity. This dual effect provides more stable and sustained control of blood pressure, reducing fluctuations and improving overall cardiovascular management.

Ifyclin 20mg Tablet 10s causes fewer side effects than some older medicines in the same group. For example, it is less likely to cause ankle swelling or a fast heartbeat, which are common with other calcium channel blockers.

Overall, Ifyclin 20mg Tablet 10s is considered a modern option for treating high blood pressure, offering effective control with good safety and comfort for patients

Ifyclin 20mg Tablet 10s is indicated for:

Essential Hypertension:

Management of primary high blood pressure in adults.

Hypertension with Co-morbidities:

Often favoured in patients with hypertension who also have chronic kidney disease (CKD) or diabetes, due to its potential renoprotective and anti-proteinuric effects.

Effective Blood Pressure Control:

Provides sustained 24-hour reduction in both systolic and diastolic blood pressure.

Reduced Sympathetic Activity:

Blocking N-type channels helps counteract the body's natural reflex to raise heart rate when blood pressure drops, offering better cardiac protection.

Lower Risk of Peripheral Oedema:

Due to its venodilatory effect resulting from sympathetic suppression, Cilnidipine is often associated with a lower incidence or severity of ankle swelling compared to other dihydropyridine CCBs.

Potential Renoprotection:

Evidence suggests it may help reduce proteinuria in hypertensive patients with renal damage.

When taken as directed, Ifyclin 20mg Tablet 10s is generally safe. Side effects are usually mild, temporary, and often relate to its blood vessel-widening effect (vasodilation).

Common Side Effects (Mild and temporary):

• Headache

• Flushing (warmth or redness in the face or neck)

• Dizziness

• Palpitations (awareness of heartbeat)

• Nausea or stomach discomfort

• Fatigue

Serious Side Effects (Stop taking the medicine and seek urgent medical attention if you experience):

• Severe Allergic Reaction (Anaphylaxis): Rash, intense itching, swelling of the face, throat, or tongue, difficulty breathing, or severe dizziness.

• Severe Hypotension (Low Blood Pressure Crisis): Extreme dizziness, fainting, or inability to stand up.

• Worsening Angina or New Chest Pain: Chest discomfort or pain that is new or getting worse.

• Signs of Liver Damage (Very Rare): Yellowing of the skin or eyes (jaundice), persistent nausea, unexplained fatigue, or pain in the upper right abdomen.

• Administration: Ifyclin 20mg Tablet 10s is taken orally, typically once daily.
• Timing: Take the medication at the same time each day to ensure stable blood drug levels.
• Dosage: The dosage will be determined by a healthcare provider based on the severity of hypertension and individual response. The usual starting dose for adults ranges from 5mg to 10mg once daily, and the maximum recommended daily dose is typically 20mg. Never adjust the dose (including strength or format) of Ifyclin 20mg Tablet 10s without medical advice.
• Food: Can be taken with or without food, unless specifically directed otherwise by your physician.

• Regular Monitoring: Always check your blood pressure regularly as instructed by your doctor while taking Ifyclin 20mg Tablet 10s.

• Postural Change: To minimise dizziness, especially in the morning, stand up slowly when getting out of bed or rising from a chair.

• Avoid Grapefruit: Strictly avoid grapefruit products while on this medication.

• Never Self-Adjust: Do not change your prescribed dosage or stop treatment with Ifyclin 20mg Tablet 10s without consulting your healthcare provider.

• Store Ifyclin 20mg Tablet 10s at room temperature, away from excessive heat and moisture.

• Keep the tablets/capsules in their original blister packaging or container.

• Ensure the medicine is kept out of the sight and reach of children and pets.

• Grapefruit Juice: Grapefruit and its juice inhibit the CYP3A4 enzyme responsible for metabolising Ifyclin 20mg Tablet 10s. This can increase the concentration of the drug in the blood, leading to a higher risk of exaggerated side effects (e.g., severe hypotension, dizziness). Avoid or minimise consumption of grapefruit products while taking Ifyclin 20mg Tablet 10s.

• Strong CYP3A4 Inhibitors (e.g., Ketoconazole, Itraconazole, HIV protease inhibitors): Can increase Ifyclin 20mg Tablet 10s plasma levels, increasing the risk of adverse effects from Ifyclin 20mg Tablet 10s.

• Strong CYP3A4 Inducers (e.g., Rifampin, Phenytoin): Can decrease Ifyclin 20mg Tablet 10s plasma levels, reducing the blood pressure-lowering efficacy of Ifyclin 20mg Tablet 10s.

• Other Antihypertensives (e.g., Beta-Blockers, ACE Inhibitors, Diuretics): The combination can lead to an additive blood pressure-lowering effect. Close monitoring of blood pressure is necessary when initiating combination therapy with Ifyclin 20mg Tablet 10s

• Severe Hypotension (Low Blood Pressure): Ifyclin 20mg Tablet 10s is contraindicated or requires extreme caution in patients with existing severe low blood pressure.

• Cardiogenic Shock/Severe Aortic Stenosis: Use with caution, as excessive vasodilation can sometimes worsen these severe cardiovascular conditions.

• Severe Hepatic Impairment: Requires close medical supervision and potential dose reduction.

The prescribed daily dose will vary. The usual adult starting dose for Ifyclin 20mg Tablet 10s is typically 5mg or 10mg once daily. The maintenance dose can range up to a maximum of 20mg once daily, depending on the therapeutic response.

An overdose of Ifyclin 20mg Tablet 10s is primarily characterised by severe and persistent hypotension (dangerously low blood pressure) and reflex tachycardia. Action Required: Seek immediate emergency medical care. Treatment will focus on stabilising the patient, typically involving monitoring vital signs, administering IV fluids, and potentially vasopressors to manage circulation.

If a dose of Ifyclin 20mg Tablet 10s is missed, take it as soon as you remember. However, if it is almost time for your next scheduled dose (e.g., within 12 hours), skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for a missed one.