Perindosyl Plus 4mg/1.25mg Tablet

Perindosyl Plus 4mg/1.25mg Tablet is a medicine used to treat hypertension (high blood pressure). It is a combination of two medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce the chances of any future heart attack and stroke. Perindosyl Plus 4mg/1.25mg Tablet should be taken on empty stomach, preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor?s advice while taking this medicine. Nausea, taste change, diarrhea, and indigestion are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Let your doctor know about cough or throat irritation that does not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. If dizziness happens, rise slowly from sitting position or avoid driving. Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function and the levels of salts such as potassium checked regularly to make sure that this medicine is working properly.

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Written by: Syed Jommy Abbas, B. Pharma

Reviewed by: Dr. Devika Rani, MBBS

Last updated on: 24-06-2025

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Perindosyl Plus 4mg/1.25mg Tablet
Perindosyl Plus 4mg/1.25mg Tablet

Elder Pharmaceuticals Ltd.

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Benefits of Perindosyl Plus 4mg/1.25mg Tablet

Hypertension (high blood pressure)

In Hypertension (high blood pressure) Perindosyl Plus 4mg/1.25mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side Effects of Perindosyl Plus 4mg/1.25mg Tablet

The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Diarrhea, Stomach pain, Constipation, Vomiting, Headache, Vertigo, Dizziness, Altered vision, Numbness, Ringing in ear, Breathlessness, Indigestion, Allergic reaction, Skin rash, Itching, Cramps, Fatigue']

Directions for Use

Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Perindosyl Plus 4mg/1.25mg Tablet is to be taken empty stomach.

How it works

Perindosyl Plus 4mg/1.25mg Tablet is a combination of two medicines: Perindopril and indapamide which lower blood pressure effectively. Perindopril is an angiotensin-converting enzyme (ACE) inhibitor. It works by reducing stress on the heart and relaxing blood vessels so that blood flows more smoothly and the heart can pump blood more efficiently. Indapamide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Alcohol

Alcohol

Unsafe: Avoid consuming alcohol with Perindosyl Plus 4mg/1.25mg Tablet as it is deemed unsafe.

Pregnancy

Pregnancy

Seek medical advice from your doctor: Perindosyl Plus 4mg/1.25mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.

Breast feeding

Breast feeding

Safe when prescribed by an expert: Perindosyl Plus 4mg/1.25mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

Driving

Not Safe: Perindosyl Plus 4mg/1.25mg Tablet may cause side effects which could affect your ability to drive. Perindosyl Plus 4mg/1.25mg Tablet usually does not affect alertness but dizziness or weakness due to low blood pressure may occur in some patients. This may affect your driving ability.

Kidney

Kidney

Caution Advised: Perindosyl Plus 4mg/1.25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Perindosyl Plus 4mg/1.25mg Tablet may be needed. Doctor consultation is advised. Caution should be advised in patients with renal impairment.

Liver

Liver

Caution Advised: Perindosyl Plus 4mg/1.25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Perindosyl Plus 4mg/1.25mg Tablet may be needed. Doctor consultation is advised.

What If You Forget to take Perindosyl Plus 4mg/1.25mg Tablet?

If a dose of Perindosyl Plus 4mg/1.25mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Storage Advice

Store in a cool and dry place, and keep the temperature below 30�C

Quick Tips for Perindosyl Plus 4mg/1.25mg Tablet

You have been prescribed Perindosyl Plus 4mg/1.25mg Tablet for the treatment of high blood pressure. It also lowers your risk of stroke and heart attack. Perindosyl Plus 4mg/1.25mg Tablet may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Inform you doctor about any cough, or throat irritation that doesn't go away. Perindosyl Plus 4mg/1.25mg Tablet may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth. Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine. Do not take Perindosyl Plus 4mg/1.25mg Tablet if you�re pregnant or planning pregnancy. It can cause birth defects or be fatal to your unborn baby.

Manufacturer Address

'Elder House' Plot No. C-9, Dalia Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai ‚ 400053.

Disclaimer

PlatinumRx is committed to providing reliable and accurate information to support informed customer decisions. However, all information made available on the Platform, including product descriptions, comparisons, and other content, is provided solely for general informational purposes. Such information is not intended to diagnose, prevent, treat, or cure any medical condition, nor should it be relied upon as a substitute for professional medical advice, diagnosis, or treatment.

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