Isoniazid

Uses

Isoniazid is used in the treatment of tuberculosis. It is also used to treat inactive (latent) TB.

How it Works

How Isoniazid works: Isoniazid is an antibiotic that kills the bacteria causing tuberculosis.

Side Effects

Common side effects of Isoniazid include peripheral neuropathy (tingling and numbness in the feet and hands), hepatitis (inflammation of the liver), skin rash, lethargy, and increased liver enzymes.

Expert Advice

  • Your doctor has prescribed Isoniazid to treat your infection and alleviate symptoms.
  • Isoniazid is best taken on an empty stomach.
  • You must also take a vitamin B6 supplement while on Isoniazid.
  • Inform your doctor immediately if you experience any of the following symptoms:
    • Vision changes
    • Loss of appetite
    • Tiredness
    • Stomach pain
    • Nausea or vomiting
    • Yellowing of the skin or eyes
    • Dark-colored urine

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Frequently asked questions

Yes, Isoniazid is safe when taken at prescribed doses and durations as directed by a healthcare provider.
Isoniazid exhibits weak inhibitory activity on monoamine oxidase (MAO) enzymes but is not used as a monoamine oxidase inhibitor (MAOI).
No, Isoniazid differs in chemical structure and mechanism of action from sulfa drugs.
Isoniazid is an antibiotic used for the prevention and treatment of tuberculosis (TB), a serious bacterial infection primarily affecting the lungs.
Isoniazid is a primary antibiotic for tuberculosis treatment and should not be confused with chemotherapy drugs used for cancer.
Isoniazid does not interact with common oral contraceptives, but the tuberculosis treatment drug rifampin can reduce the effectiveness of birth control pills.
Isoniazid is an inhibitor of a key liver enzyme system that processes and eliminates various drugs from the body.
Isoniazid is a bacteriostatic antibiotic that inhibits the growth of tuberculosis-causing bacteria by disrupting their cell wall formation.
Unusual tiredness, constipation, or acne may occur during Isoniazid treatment. Consult your doctor about all medications you are taking to prevent interactions.
Weight changes, hair loss, diarrhea, and menstrual changes are not recognized side effects of Isoniazid, although some may occur during multi-drug tuberculosis treatment.
There are no known serious interactions between Isoniazid and ibuprofen, acetaminophen (Tylenol), naproxen (Aleve), amoxicillin, or any active ingredients in Nyquil or Mucinex. Inform your doctor about all medications you are taking to avoid potential interactions.
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