Isoniazid + Rifampicin

Uses

Rifampicin and Isoniazid are used in the treatment of tuberculosis.

How it Works

How Rifampicin and Isoniazid Work Rifampicin and Isoniazid are a combination of two antibiotics that treat tuberculosis (TB). Rifampicin inactivates a bacterial enzyme, RNA polymerase, which is essential for TB bacteria to produce vital proteins and reproduce. Isoniazid prevents these bacteria from forming their protective covering. Together, they kill the bacteria and eradicate the infection.

Side Effects

Common side effects of Rifampicin and Isoniazid include vomiting, nausea, peripheral neuropathy (tingling and numbness in the hands and feet), abdominal pain, skin rash, itching, hepatitis (viral infection of the liver), dizziness, lethargy, and low blood platelets.

Expert Advice

You have been prescribed Rifampicin + Isoniazid for the treatment of tuberculosis.
Complete the full course of the medication, even if you feel better. Stopping it early may cause the infection to return.
Take the medication on an empty stomach, preferably at the same time every day.
It may cause discolouration of your urine, sweat, saliva, and tears to a reddish-orange color. This is normal and not harmful.
Your doctor may check your liver function before starting treatment and regularly thereafter.
Inform your doctor if you notice any of the following symptoms:
- Yellowing of the eyes or skin
- Dark urine
- Stomach pain
Avoid drinking alcohol while taking Rifampicin + Isoniazid, as this may increase the risk of liver side effects.
Use an alternative or additional contraceptive method (such as condoms or a diaphragm) to prevent pregnancy while taking Rifampicin + Isoniazid, as it may reduce the effectiveness of hormonal contraceptives like the pill.
Do not take indigestion remedies (antacids) within at least two hours of taking Rifampicin + Isoniazid.

Other Combinations

Ethambutol + Isoniazid + Piperine + Pyrazinamide + Rifampicin

Ethambutol + Isoniazid + Pyrazinamide + Rifampicin

Ethambutol + Isoniazid + Pyrazinamide + Rifampicin + Vitamin B6 (Pyridoxine)

Ethambutol + Isoniazid + Rifampicin

Ethambutol + Isoniazid + Rifampicin + Vitamin B6 (Pyridoxine)

Isoniazid + Piperine + Rifampicin

Isoniazid + Pyrazinamide + Rifampicin

Isoniazid + Pyrazinamide + Rifampicin + Vitamin B6 (Pyridoxine)

Isoniazid + Rifampicin + Vitamin B6 (Pyridoxine)

Isoniazid + Sodium aminosalicylate

Isoniazid + Vitamin B6 (Pyridoxine)

Related Medications

Salt Composition

Isoniazid + Rifampicin 125mg

Lynacox Tablet DT

Lancer Healthcare Pvt. Ltd.

Strip of 10 tablets

MRP ₹11.2

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

R Cinex 450/300mg Tablet 10s

Lupin Ltd.

Strip of 10 tablets

MRP ₹128.7

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Mexcox Plus 450mg/300mg Tablet

Mexon Healthcare Ltd.

Strip of 10 tablets

MRP ₹68.7

Salt Composition

Isoniazid 300mg + Rifampicin 100mg

Coxwin ZH Kid 100 mg/300 mg Tablet

Marc Laboratories Pvt. Ltd.

Strip of 10 tablets

MRP ₹20.2

Salt Composition

Isoniazid 150mg + Rifampicin 300mg

Scc 2 LW 300 mg/150 mg Tablet

Maneesh Pharmaceuticals Ltd.

Strip of 10 tablets

MRP ₹38.5

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Tubachem 450mg/300mg Tablet

Chemo Biological

Strip of 10 tablets

MRP ₹48

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

COXINEX 450MG/300MG CAPSULE

Aristo Pharmaceuticals Pvt. Ltd.

Strip of 10 capsules

MRP ₹65.1

Salt Composition

Isoniazid 75mg + Rifampicin 150mg

Ticinex 150mg/75mg Tablet

Themis Medicare Ltd.

Strip of 6 tablets

MRP ₹11.7

Salt Composition

Isoniazid 50mg + Rifampicin 100mg

Montonex Kid 100mg/50mg Tablet

Shreya Life Sciences Pvt. Ltd.

Strip of 10 tablets

MRP ₹11.3

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Rifampirose Forte Tablet

Medirose drug & pharma

Strip of 10 tablets

MRP ₹42.9

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Carin 450/300mg Capsule 10s

Pan Pharmaceuticals Ltd.

Strip of 10 capsules

MRP ₹26

Salt Composition

Isoniazid 75mg + Rifampicin 150mg

RI Kid Tablet DT

Hippo Labs Pvt. Ltd.

Strip of 10 tablets

MRP ₹22

Salt Composition

Isoniazid 100mg + Rifampicin 150mg

Faminex Kid 150 mg/100 mg Tablet

Lark Laboratories Ltd.

Strip of 10 tablets

MRP ₹18.8

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Antibin Forte 450/300mg Tablet 10s

Medispan Ltd.

Strip of 10 tablets

MRP ₹55.2

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Faminex 450 mg/300 mg Capsule

Lark Laboratories Ltd.

Strip of 10 capsules

MRP ₹56.2

Salt Composition

Isoniazid 50mg + Rifampicin 100mg

Ticinex Kid 100 mg/50 mg Tablet

Themis Medicare Ltd.

Strip of 10 tablets

MRP ₹13.3

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Rikox 450/300mg Tablet 10s

Aan Pharma Pvt. Ltd.

Strip of 10 tablets

MRP ₹68

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Wycox 450mg/300mg Capsule

Vostok & Wilcure Remedies

Strip of 10 capsules

MRP ₹59.5

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Zadcox Plus 450mg/300mg Capsule

Smilax Pharmaceuticals

Strip of 10 capsules

MRP ₹54

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Rifaplus IN 450/300mg Capsule 10s

Radicura Pharma Pvt. Ltd.

Strip of 10 capsules

MRP ₹43.5

Salt Composition

Isoniazid 75mg + Rifampicin 150mg

Vicox 3 Tablet

Shrinivas Gujarat Laboratories Pvt. Ltd.

Strip of 10 tablets

MRP ₹48

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Rifalin I 450 mg/300 mg Tablet

LIncoln Pharmaceuticals Ltd.

Strip of 10 tablets

MRP ₹52.5

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Secox 2 Capsule

Sierra Pharmaceuticals Ltd.

Strip of 10 capsules

MRP ₹63

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Rifazid A Forte Capsule 10s

Acichem Laboratories

Strip of 10 capsules

MRP ₹60

Salt Composition

Isoniazid 300mg + Rifampicin 450mg

Anticox II 450/300mg Tablet 4s

Torrent Pharmaceuticals Ltd.

Strip of 4 tablets

MRP ₹18.8

Frequently asked questions

What is Rifampicin+Isoniazid?

Rifampicin+Isoniazid is a combination medication used to treat tuberculosis. Rifampicin inhibits bacterial RNA-polymerase, essential for bacterial protein synthesis and reproduction, while Isoniazid prevents the bacteria from forming a protective covering. Together, they effectively kill the bacteria and eliminate the infection.

Does Rifampicin+Isoniazid change urine color?

Yes, Rifampicin+Isoniazid can cause urine, skin, sweat, saliva, tears, and feces to turn brownish-red or orange. This change is harmless.

What is the best time to take Rifampicin+Isoniazid?

Take Rifampicin+Isoniazid as directed by your doctor, preferably on an empty stomach—one hour before or two hours after meals.

What are the storage and disposal instructions for Rifampicin+Isoniazid?

Store the medication in its original container, tightly closed, following the storage instructions on the label. Dispose of any unused medicine properly to prevent accidental ingestion by pets, children, or others.

Does Rifampicin+Isoniazid affect the effectiveness of birth control pills?

Yes, Rifampicin+Isoniazid can reduce the effectiveness of birth control pills. Consult your doctor about alternative contraceptive methods that do not affect hormone levels, such as condoms or diaphragms.

What is the most important information to know about Rifampicin+Isoniazid?

Complete the full course of the prescribed medication, even if you feel better. Avoid alcohol during treatment to reduce the risk of liver damage. Contact your doctor immediately if you experience vision changes, loss of appetite, fatigue, stomach pain, nausea, vomiting, yellowing of the skin or eyes, or dark urine.

;

Flat ₹100 off on first app order | Use Code: APP100 |

Flat ₹100 off on first app order

USE CODE: APP100

Download Now