Senasof Tablet 10s is a plant-based laxative used for the short-term relief of occasional constipation. It is made from natural ingredients found in the senna plant and works by helping stimulate the muscles of the bowel when they become sluggish. By encouraging the natural movement of waste through the digestive system, Senasof Tablet 10s helps make bowel movements easier and more regular. It is commonly used when constipation causes hard stools, difficulty passing stool, or infrequent bowel movements.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Rohit Kolhe, MBBS
Last updated on: 19-06-2026
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Senasof Tablet 10s is a plant-based laxative used for the short-term relief of occasional constipation. It is made from natural ingredients found in the senna plant and works by helping stimulate the muscles of the bowel when they become sluggish. By encouraging the natural movement of waste through the digestive system, Senasof Tablet 10s helps make bowel movements easier and more regular. It is commonly used when constipation causes hard stools, difficulty passing stool, or infrequent bowel movements.
Senasof Tablet 10s is a natural laxative used to relieve occasional constipation and help restore regular bowel movements. Constipation can occur when stool moves too slowly through the large intestine, allowing too much water to be absorbed. This can make the stool hard, dry, and difficult to pass, often causing discomfort, bloating, and straining during bowel movements.
Senasof Tablet 10s contains natural plant-based ingredients called sennosides. After you take the medicine, these ingredients pass through the stomach and small intestine without being absorbed. Once they reach the large intestine, they are converted into an active form by the natural bacteria that normally live in the gut.
The active ingredients help stimulate the muscles of the colon, encouraging the bowel to move waste through the digestive tract more effectively. At the same time, they help keep more water in the stool, making it softer and easier to pass.
Senasof Tablet 10s may be indicated by your physician or used for:
Managing sluggish bowel movements in patients taking prescription opioid pain medications, which naturally slow digestion.
Preventing painful straining after childbirth or pelvic surgeries by keeping stools soft and moving.
Assisting in clearing out the bowel before specific medical exams, such as a colonoscopy or X-ray imaging, under clinical guidance.
Senasof Tablet 10s may provide benefits such as:
Consult your doctor if you experience any unusual, severe, or persistent symptoms while using Senasof Tablet 10s.
Senasof Tablet 10s operates via a localized, prodrug-activated physiological pathway within the lower gastrointestinal tract. The primary active constituents, sennosides A and B, are dimeric anthraquinone glycosides that resist hydrolytic cleavage by gastric acid and upper intestinal brush-border enzymes, passing intact into the cecum and colon.
Upon entering the large intestine, indigenous colonic microflora (specifically Bacteroides species) metabolize these glycosides, cleaving the sugar moieties to liberate the active free metabolite, rheinanthrone.
Rheinanthrone exerts a direct, dual-action effect on the colonic mucosa. First, it stimulates the submucosal and myenteric plexuses, inducing propulsive motor waves (peristalsis) while inhibiting non-propulsive segmental contractions.
Combining them can cause your body to lose potassium too quickly, leading to severe muscle weakness, cramps, or irregular heart rhythms.
If the laxative causes your potassium levels to drop, it dramatically increases the risk of dangerous, toxic side effects from your heart medication.
Severe diarrhea caused by laxative overuse can flush birth control pills out of your system before they absorb, reducing their protection.
If you miss a scheduled evening dose of Senasof Tablet 10s and you still require relief from constipation, you may take the tablet as soon as you remember. However, keep in mind that it takes 6 to 12 hours to work, so taking it during the daytime may cause a bowel movement while you are away from home. If it is almost time for your next scheduled dose, skip the missed tablet completely. Do not take a double dose to make up for a forgotten one.
Therapeutic Class
Gastrointestinal Formulations / Evacuants and Stimulant Laxatives
Action Class
Stimulant Laxative / Myenteric Plexus Agonist and Secretagogue
Chemical Class
Anthraquinone Glycoside Botanical Complex
Habit Forming
No (When used strictly short-term as directed)
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