Vincristine GLS 1 Injection is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.Vincristine GLS 1 Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.� you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
Written by: Shubham Kumar Singh, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 24-06-2025
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Vincristine GLS 1 Injection is an anti-cancer medication used in the treatment of breast cancer, non-small cell lung cancer, pancreatic cancer, kidney cancer, blood cancer, multiple myeloma, lymphomas and bone cancer.Vincristine GLS 1 Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include hair loss, peripheral neuropathy (tingling and numbness of feet and hand), and constipation. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.� you are suggested to avoid direct contact of medicine with eyes, as it may cause eye irritation.
Breast cancer / Non-small cell lung cancer / Pancreatic cancer / Kidney cancer / Blood cancer / Multiple myeloma / Lymphomas
In Breast cancer : Vincristine GLS 1 Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Vincristine GLS 1 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.In Non-small cell lung cancer Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Vincristine GLS 1 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.In Pancreatic cancer
Side effects of Vincristine GLS Injection The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Vincristine GLSHair loss Peripheral neuropathy (tingling and numbness of feet and hand)Constipation
How to use Vincristine GLS Injection Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Vincristine GLS Injection works Vincristine GLS 1 Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Vincristine GLS 1 Injection . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Vincristine GLS 1 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Vincristine GLS 1 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
Vincristine GLS 1 Injection may cause side effects which could affect your ability to drive.
Kidney
Vincristine GLS 1 Injection should be used with caution in patients with kidney disease. Dose adjustment of Vincristine GLS 1 Injection may be needed. Doctor consultation is advised.
Liver
Vincristine GLS 1 Injection should be used with caution in patients with liver disease. Dose adjustment of Vincristine GLS 1 Injection may be needed. Doctor consultation is advised.
Store in a refrigerator (2 - 8�C). Do not freeze.
Vincristine GLS 1 Injection is given as a drip in the vein under the supervision of a doctor. Do not skip any dose and complete the course as suggested by your doctor. Use an effective method of birth control to avoid pregnancy while taking this medication. Your doctor may get regular blood tests done to monitor your blood cell count, platelet count and liver function. Inform your doctor if you experience skin rash, swelling of face or lips and trouble breathing.
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