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Sitagliptin

Uses

Sitagliptin is used in the treatment of type 2 diabetes mellitus. It is used in conjunction with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

How it Works

How Sitagliptin works Sitagliptin is an antidiabetic medication. It functions by enhancing the release of insulin from the pancreas and reducing the levels of hormones that elevate blood sugar. This action helps lower both fasting and post-meal sugar levels.

Side Effects

Common side effects of Sitagliptin include headache, nasopharyngitis (inflammation of the throat and nasal passages), nausea, diarrhea, hypoglycemia (low blood glucose level), conjunctivitis, cough, vomiting, constipation, and pancreatic inflammation.

Expert Advice

  • Sitagliptin should be taken at the same time every day to help you remember to take it.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as:
    • Cold sweats
    • Cool, pale skin
    • Tremor
    • Anxiety
  • Be cautious while driving or operating machinery until you know how Sitagliptin affects you.
  • Inform your doctor if you notice joint pains or develop symptoms such as:
    • Stomach pain
    • Nausea
    • Vomiting
  • Continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines alongside this medication.
  • The chances of weight gain and low blood sugar are lower compared to other diabetes medicines.
  • Monitor your blood sugar level regularly while taking this medicine.

Other Combinations

Gliclazide + Sitagliptin

Metformin + Pioglitazone + Sitagliptin

Dapagliflozin + Metformin + Sitagliptin

Dapagliflozin + Sitagliptin

Glimepiride + Metformin + Sitagliptin

Metformin + Sitagliptin

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Frequently asked questions

Sitagliptin is not known to cause weight gain by itself. However, maintaining a healthy weight is crucial for diabetes management. Consult your doctor if you experience weight gain while taking Sitagliptin.
Sitagliptin is safe for your kidneys if kidney function is normal. Inform your doctor of any past or present kidney issues, as dose adjustments may be necessary.
If you miss a dose, take it as soon as you remember. If it's close to the next dose, skip the missed one and resume your regular schedule. Do not take two doses at once.
Continue taking Sitagliptin as long as your doctor advises. It helps manage blood sugar but does not cure diabetes, and discontinuation should only occur after consulting your doctor.
Yes, Sitagliptin is safe for long-term use, which can last months or even years, without harmful effects. Continue as directed by your doctor, as it helps control blood sugar but does not cure diabetes.
Yes, Sitagliptin can cause low blood sugar (hypoglycemia), especially if combined with other antidiabetic medications or insulin. Skipping meals or excessive exercise can also lead to low levels. Monitor your blood sugar regularly and consult your doctor if you notice significant drops.
Yes, managing your diet and exercise is essential while taking Sitagliptin. Healthy food choices and physical activity are vital for effective blood sugar management. Consider consulting a dietitian for a personalized diet plan and aim for at least thirty minutes of exercise daily.
Sitagliptin is safe when taken as prescribed, but rare serious side effects can occur, including pancreatitis and heart failure. Seek immediate medical attention if you experience severe abdominal pain or have a history of heart or kidney issues.
Taking more than the prescribed dose may lead to low blood sugar (hypoglycemia). Monitor your levels closely for 24 hours. Mild symptoms can often be treated with sugary foods, but consult your doctor for further guidance, as severe hypoglycemia can be life-threatening.
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