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Glimepiride + Metformin + Sitagliptin
Uses
Sitagliptin, Glimepiride, and Metformin are used in the treatment of type 2 diabetes mellitus.
How it Works
How Sitagliptin + Glimepiride + Metformin works Sitagliptin, Glimepiride, and Metformin is a combination of three antidiabetic medications. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that stimulate the pancreas to release more insulin. It also signals the liver to reduce glucose production when blood sugar levels are elevated. Glimepiride lowers blood sugar by prompting the pancreas to produce insulin, which is essential for breaking down sugar in the body, and by enhancing the body's efficiency in using insulin. Metformin reduces the amount of glucose absorbed from food and decreases glucose production by the liver. Additionally, it enhances the body's response to insulin, a natural substance that regulates blood sugar levels.
Side Effects
Common side effects of Sitagliptin, Glimepiride, and Metformin include hypoglycemia (low blood glucose level), headache, nausea, diarrhea, abdominal pain, constipation, and vomiting.
Expert Advice
- Prefer taking Sitagliptin + Glimepiride + Metformin after a meal or with a snack, as this will reduce the likelihood of an upset stomach.
- Sitagliptin + Glimepiride + Metformin may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medications, alcohol, or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience symptoms of hypoglycemia, such as:
- Fatigue
- Dizziness
- Cold sweats
- Tremor
- Anxiety
- If you experience unusual thirst, increased urination, and fatigue, inform your doctor. These may be signs of excessive sugar in your blood, indicating that your dose may need adjustment.
- Monitor your blood sugar regularly while taking this medication.
- Lifestyle changes such as a low sugar diet, regular exercise, weight loss, avoiding smoking, and reducing alcohol intake may enhance the effectiveness of this medication.