Gliclazide + Sitagliptin

Uses

Gliclazide and Sitagliptin are used in the treatment of type 2 diabetes mellitus.

How it Works

How Gliclazide and Sitagliptin work Gliclazide and Sitagliptin is a combination of two antidiabetic medications. Gliclazide increases the amount of insulin produced by the pancreas. Insulin reduces blood sugar levels by assisting cells in using and storing glucose. Sitagliptin helps to control blood sugar levels by increasing substances (incretins) in the body that stimulate the pancreas to release more insulin. It also signals the liver to stop producing glucose when blood sugar levels are elevated.

Side Effects

Common side effects of Gliclazide and Sitagliptin include upper respiratory tract infection, nasopharyngitis (inflammation of the throat and nasal passages), headache, hypoglycemia (low blood glucose level), abdominal pain, nausea, vomiting, indigestion, diarrhea, and constipation.

Expert Advice

  • Prefer taking Gliclazide + Sitagliptin after a meal or with a snack to reduce the likelihood of an upset stomach.
  • Gliclazide + Sitagliptin may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medications, alcohol, or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience symptoms of hypoglycemia, such as:
    • Fatigue
    • Dizziness
    • Cold sweats
    • Tremors
    • Anxiety
  • Inform your doctor if you experience:
    • Unusual thirst
    • Increased frequency of urination
    • Fatigue
  • These symptoms may indicate too much sugar in your blood, and your dosage may need adjustment.
  • Regularly monitor your blood sugar levels while taking this medication.
  • Implementing lifestyle changes, such as:
    • Following a low-sugar diet
    • Exercising regularly
    • Losing weight
    • Avoiding smoking
    • Reducing alcohol intake
  • These changes may enhance the effectiveness of this medication.
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