MoleculeSalt Composition

Nortriptyline 10mg + Pregabalin 50mg + Vitamin B12 (Methylcobalamin) 1500mcg

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PREMAC PLUS 50mg/10mg/1500mcg Tablet

PREMAC PLUS 50mg/10mg/1500mcg Tablet

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Long Expiry
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15 Days Easy
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Long Expiry

Long Expiry
(>8 Months)

Used In

Treatment of Neuropathic pain

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More About PREMAC PLUS 50mg/10mg/1500mcg Tablet

Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Treatment of Neuropathic painTreatment of Neuropathic pain

In Treatment of Neuropathic pain : PREMAC PLUS 50mg/10mg/1500mcg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that are essential for improving nerve conduction.Taking PREMAC PLUS 50mg/10mg/1500mcg Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.In Treatment of Neuropathic pain : PREMAC PLUS 50mg/10mg/1500mcg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles, or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that are essential for improving nerve conduction.Taking PREMAC PLUS 50mg/10mg/1500mcg Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to take it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep taking the medicine until your doctor advises you to stop.

Side Effects

Side effects of PREMAC PLUS Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of PREMAC PLUSConstipation Weight gain Orthostatic hypotension (sudden lowering of blood pressure on standing)Dizziness Increased heart rate Sleepiness Tiredness Blurred vision Dryness in mouth Uncoordinated body movements Decreased appetite Nausea Difficulty in urination Vomiting DiarrheaSide effects of PREMAC PLUS Tablet The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of PREMAC PLUSConstipation Weight gain Orthostatic hypotension (sudden lowering of blood pressure on standing)Dizziness Increased heart rate Sleepiness Tiredness Blurred vision Dryness in mouth Uncoordinated body movements Decreased appetite Nausea Difficulty in urination Vomiting Diarrhea

How to use

How to use PREMAC PLUS Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. PREMAC PLUS 50mg/10mg/1500mcg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.How to use PREMAC PLUS Tablet Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. PREMAC PLUS 50mg/10mg/1500mcg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.

How it works

How PREMAC PLUS Tablet works PREMAC PLUS 50mg/10mg/1500mcg Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).How PREMAC PLUS Tablet works PREMAC PLUS 50mg/10mg/1500mcg Tablet is a combination of three medicines: Pregabalin, Nortriptyline and Methylcobalamin. Pregabalin is an alpha 2 delta ligand which decreases pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Alcohol

Not Safe: Consuming alcohol with PREMAC PLUS 50mg/10mg/1500mcg Tablet may lead to excessive drowsiness.Not Safe: Consuming alcohol with PREMAC PLUS 50mg/10mg/1500mcg Tablet may lead to excessive drowsiness.

Pregnancy

PREMAC PLUS 50mg/10mg/1500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.PREMAC PLUS 50mg/10mg/1500mcg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.

Breast feeding

PREMAC PLUS 50mg/10mg/1500mcg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.PREMAC PLUS 50mg/10mg/1500mcg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

PREMAC PLUS 50mg/10mg/1500mcg Tablet may cause side effects which could affect your ability to drive.As PREMAC PLUS 50mg/10mg/1500mcg Tablet may affect your alertness which may affect your ability to drive.PREMAC PLUS 50mg/10mg/1500mcg Tablet may cause side effects which could affect your ability to drive.As PREMAC PLUS 50mg/10mg/1500mcg Tablet may affect your alertness which may affect your ability to drive.

Kidney

PREMAC PLUS 50mg/10mg/1500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment of PREMAC PLUS 50mg/10mg/1500mcg Tablet may be needed. Doctor consultation is advised.PREMAC PLUS 50mg/10mg/1500mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment of PREMAC PLUS 50mg/10mg/1500mcg Tablet may be needed. Doctor consultation is advised.

Liver

PREMAC PLUS 50mg/10mg/1500mcg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of PREMAC PLUS 50mg/10mg/1500mcg Tablet may not be needed in these patients. Please consult your doctor.PREMAC PLUS 50mg/10mg/1500mcg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of PREMAC PLUS 50mg/10mg/1500mcg Tablet may not be needed in these patients. Please consult your doctor.

What if I forget to take it?

If a dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.If a dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Manufacturer Address

8th Floor, 'Devapth', Besides Lal Bungalows, CG Road Ahmedabad, 380006 Gujarat, INDIA

Frequently asked questions

Regular doctor visits may be necessary after starting PREMAC PLUS 50mg/10mg/1500mcg Tablet. Consult your doctor if symptoms do not improve or if side effects persist.
PREMAC PLUS 50mg/10mg/1500mcg Tablet is a combination of pregabalin, nortriptyline, and methylcobalamin used to treat nerve pain by calming overactive nerves and aiding nerve regeneration.
If you suspect an overdose of PREMAC PLUS 50mg/10mg/1500mcg Tablet, contact your doctor or seek emergency help immediately, even if you feel fine.
Yes, PREMAC PLUS 50mg/10mg/1500mcg Tablet has an expiration date. Do not use it after this date.
If you miss a dose of PREMAC PLUS 50mg/10mg/1500mcg Tablet, take it as soon as you remember unless it's close to your next dose. Do not double up on doses.
Initial benefits from PREMAC PLUS 50mg/10mg/1500mcg Tablet may be noticed after 2 weeks, with full effects taking 2-3 months or longer.
PREMAC PLUS 50mg/10mg/1500mcg Tablet may affect sexual function, causing decreased desire, erectile dysfunction, or difficulty reaching orgasm. Discuss any issues with your doctor without stopping the medication.
No, do not stop taking PREMAC PLUS 50mg/10mg/1500mcg Tablet abruptly even if your pain improves. Consult your doctor for guidance on tapering the dose to avoid withdrawal symptoms.
Store PREMAC PLUS 50mg/10mg/1500mcg Tablet in a cool, dry place out of reach of children. Dispose of unused medications properly to prevent accidental ingestion.
Yes, PREMAC PLUS 50mg/10mg/1500mcg Tablet can cause drowsiness or sudden sleep episodes. Avoid driving or operating machinery until you know how it affects you.
PREMAC PLUS 50mg/10mg/1500mcg Tablet may impair your alertness. Avoid alcohol, grapefruit products, and excessive sun exposure while taking this medication.
PREMAC PLUS 50mg/10mg/1500mcg Tablet may increase hunger, leading to weight gain. To manage this, maintain a balanced diet, avoid high-calorie foods, and exercise regularly.
No, taking more than the recommended dose can increase the risk of serious side effects and toxicity. Consult your doctor if your symptoms worsen.
Serious side effects from PREMAC PLUS 50mg/10mg/1500mcg Tablet are rare but can include changes in body temperature, breathing difficulties, and mood changes. Seek medical attention if you experience these symptoms.

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References

  • Pregabalin. Sandwich, Kent: Pfizer Limited; 2009 (24 Apr. 2019)

  • Pregabalin (Prolonged Release), Methylcobalamin and Nortriptyline Hydrochloride (28th Sept. 2023)

  • Pregabalin+ Nortriptyline (28th Sept. 2023)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.

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