In Pain relief Doloforce 40mg Injection is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery. To obtain the maximum benefit, follow the prescribed instructions precisely. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.In Pain relief Doloforce 40mg Injection is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis or even after a dental (tooth-related) surgery. To obtain the maximum benefit, follow the prescribed instructions precisely. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side Effects
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine.
Doctor consultation is advised if they persist or if you're worried about them.The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine.
Doctor consultation is advised if they persist or if you're worried about them.
How to use
Your doctor or nurse will give you this medicine. Kindly do not self administer.Your doctor or nurse will give you this medicine. Kindly do not self administer.
How it works
Doloforce 40mg Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).Doloforce 40mg Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that are responsible for inflammation (pain and swelling).
Alcohol
Caution: It is important to consult your doctor regarding alcohol consumption while taking Doloforce 40mg Injection .Caution: It is important to consult your doctor regarding alcohol consumption while taking Doloforce 40mg Injection .
Pregnancy
Seek medical advice from your doctor: Doloforce 40mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.Seek medical advice from your doctor: Doloforce 40mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Safe when prescribed by an expert: Doloforce 40mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.Safe when prescribed by an expert: Doloforce 40mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
Not Safe: Doloforce 40mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.Not Safe: Doloforce 40mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
Caution Advised: Doloforce 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Doloforce 40mg Injection may be needed. Doctor consultation is advised. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.Caution Advised: Doloforce 40mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Doloforce 40mg Injection may be needed. Doctor consultation is advised. No dose adjustment is recommended in patients with mild to moderate kidney disease. Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
Caution Advised: Doloforce 40mg Injection should be used with caution in patients with liver disease. Dose adjustment of Doloforce 40mg Injection may be needed. Doctor consultation is advised.Caution Advised: Doloforce 40mg Injection should be used with caution in patients with liver disease. Dose adjustment of Doloforce 40mg Injection may be needed. Doctor consultation is advised.
What if I forget to take it?
If a dose of Doloforce 40mg Injection is missed, it's advisable to consult your doctor.If a dose of Doloforce 40mg Injection is missed, it's advisable to consult your doctor.
Manufacturer Address
208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Frequently asked questions
Are both Doloforce & PIROX medicines exactly the same?
Yes, both medicines have the same salt composition, dosage, and effectiveness. They work the same way in your body. The only difference is the brand — and PIROX option is much more affordable without compromising on quality
Is Doloforce 40mg Injection a NSAID?
Yes, Doloforce 40mg Injection is classified as a non-steroidal anti-inflammatory drug (NSAID).
Is Doloforce 40mg Injection a narcotic?
No, Doloforce 40mg Injection is not a narcotic; it is a painkiller that acts on the COX enzyme to reduce pain and inflammation.
Is Doloforce 40mg Injection a sulfa drug?
Doloforce 40mg Injection is a sulfur-containing compound that can cause serious reactions in sensitive individuals, including severe skin reactions. Inform your doctor of any allergies.
How long does Doloforce 40mg Injection work?
Doloforce 40mg Injection is a long-acting drug, and its effectiveness may improve with continued use over several weeks.
Is Doloforce 40mg Injection a blood thinner?
No, Doloforce 40mg Injection is not a blood thinner; it is a painkiller and should be avoided in patients with bleeding disorders.
Is Doloforce 40mg Injection a muscle relaxant?
No, Doloforce 40mg Injection is not a muscle relaxant; it is a painkiller that works on the COX enzyme.
Are Doloforce 40mg Injection and aspirin the same?
No, they are not the same. Both are COX inhibitors and have anti-inflammatory and analgesic properties.
Can Doloforce 40mg Injection be used with lithium?
No, Doloforce 40mg Injection should not be used with lithium as it can elevate plasma lithium levels. Consult your doctor.
Can I use Doloforce 40mg Injection for a migraine?
Doloforce 40mg Injection is not approved for migraines, but studies suggest it may effectively reduce migraine pain.
Can Doloforce 40mg Injection be used with warfarin?
No, Doloforce 40mg Injection should be avoided with warfarin due to increased bleeding risk. Monitor therapy closely if combined.
Can you get high by using Doloforce 40mg Injection?
No, Doloforce 40mg Injection is not known to cause a high; it is a non-narcotic painkiller.
Can Doloforce 40mg Injection be used with diuretics?
No, Doloforce 40mg Injection should not be used with diuretics as it can reduce their effectiveness.
Can Doloforce 40mg Injection lead to skin reactions?
Yes, Doloforce 40mg Injection can cause severe skin reactions, including exfoliative dermatitis and Stevens-Johnson Syndrome. Report any rash to your doctor immediately.
Can I use Doloforce 40mg Injection if I am diabetic?
Consult your doctor before using Doloforce 40mg Injection if you are diabetic, as it may increase the risk of renal failure.
Can I use Doloforce 40mg Injection if I am pregnant?
No, Doloforce 40mg Injection should not be used during pregnancy as it can cause serious fetal complications.
Can I use Doloforce 40mg Injection if I have asthma?
Consult your doctor before using Doloforce 40mg Injection if you have asthma, as some patients may be sensitive to NSAIDs.
Can Doloforce 40mg Injection be used in hypertension?
No, Doloforce 40mg Injection does not control hypertension and can reduce the effectiveness of antihypertensive medications. Consult your doctor if you are on such medications.
Can Doloforce 40mg Injection be used with Lisinopril?
No, Doloforce 40mg Injection should be avoided with Lisinopril as it can reduce its effectiveness in controlling blood pressure.
Can Doloforce 40mg Injection be used with Tizanidine?
Yes, Doloforce 40mg Injection can be combined with Tizanidine, as they serve different purposes in pain management.
Can you donate blood when on Doloforce 40mg Injection?
Yes, you can donate blood while taking Doloforce 40mg Injection, but inform your doctor beforehand.
Are there any alternatives to Doloforce 40mg Injection?
Yes, there are alternatives to Doloforce 40mg Injection. Consult your doctor for appropriate pain management options.
Can Doloforce 40mg Injection be used with methocarbamol?
Yes, Doloforce 40mg Injection can be safely used with methocarbamol. Always inform your doctor before starting any medication.
Can Doloforce 40mg Injection be used along with Losartan?
No, Doloforce 40mg Injection should not be combined with Losartan as it decreases the effectiveness of this antihypertensive medication.
Is Doloforce 40mg Injection effective in gout management?
Yes, Doloforce 40mg Injection is effective for treating acute gout.
Why is beta cyclodextrin added to Doloforce 40mg Injection?
Beta-cyclodextrin is added to enhance the onset of action and reduce gastric side effects of Doloforce 40mg Injection.
Can Doloforce 40mg Injection be used along with paracetamol?
Yes, Doloforce 40mg Injection can be safely combined with paracetamol. Consult your doctor before starting any medication.
What are the contraindications for Doloforce 40mg Injection?
Contraindications include allergies, bleeding tendencies, active ulcers, certain autoimmune diseases, late pregnancy, and severe liver or kidney impairment.
Can Doloforce 40mg Injection be used along with dexamethasone?
No, using Doloforce 40mg Injection with dexamethasone increases toxicity and the risk of gastrointestinal ulceration.
Can Doloforce 40mg Injection lead to difficulty in conception?
Yes, Doloforce 40mg Injection may cause reversible infertility by affecting ovarian follicle rupture. Consult your doctor before use.
Is Doloforce 40mg Injection effective in back pain management?
Yes, Doloforce 40mg Injection can help reduce back pain, but consult your doctor for a proper diagnosis before use.
What are the serious side effects of Doloforce 40mg Injection?
Serious side effects may include gastrointestinal discomfort, ulcers, bleeding, severe skin reactions, liver failure, and renal damage.
Can Doloforce 40mg Injection be used to treat menstrual cramps?
Doloforce 40mg Injection is not officially approved for menstrual cramps, but it may help alleviate the pain.
Can Doloforce 40mg Injection be used in the treatment of allergy?
No, Doloforce 40mg Injection is not intended for treating allergies; it is a painkiller.
Can I use Doloforce 40mg Injection if I have peptic ulcer disease?
No, Doloforce 40mg Injection is contraindicated in active peptic ulcer disease due to the risk of gastric ulceration.
Can Doloforce 40mg Injection be used with calcium channel blockers?
Yes, Doloforce 40mg Injection can be taken with calcium channel blockers, as NSAIDs do not reduce their effectiveness.
Can Doloforce 40mg Injection be used in the treatment of chikungunya?
Avoid using Doloforce 40mg Injection or any painkiller in cases of fever with joint pain in chikungunya, as it may increase bleeding risk. Consult your doctor first.
Can I use Doloforce 40mg Injection if I have deranged renal function?
No, Doloforce 40mg Injection should not be used if you have abnormal renal function due to the risk of renal injury.
What is the difference between Doloforce 40mg Injection and naproxen?
Both are non-selective COX inhibitors and equally effective painkillers, but naproxen has fewer gastric side effects compared to Doloforce 40mg Injection.
What is the difference between Doloforce 40mg Injection and tramadol?
Doloforce 40mg Injection is a COX inhibitor, while tramadol is a narcotic-like painkiller that can be habit-forming.
What is the difference between Doloforce 40mg Injection and meloxicam?
Both are non-selective COX inhibitors and equally effective, but meloxicam has fewer acute gastric side effects than Doloforce 40mg Injection.
What is the difference between Doloforce 40mg Injection and diclofenac?
Both Doloforce 40mg Injection and diclofenac are painkillers, but Doloforce 40mg Injection is a non-selective COX inhibitor while diclofenac is more selective for COX-2, potentially leading to fewer side effects.
What is the difference between Doloforce 40mg Injection and ketoprofen?
Both are painkillers, but ketoprofen topical gel is shown to be more effective and better tolerated than Doloforce 40mg Injection.
What is the difference between Doloforce 40mg Injection and nimesulide?
Doloforce 40mg Injection is a non-selective COX inhibitor, whereas nimesulide selectively inhibits COX-2, which may reduce side effects. Nimesulide is not recommended for children under 12.
Who should not take a Non-Steroidal Anti-Inflammatory Drug (NSAID)/ Doloforce 40mg Injection?
Patients with a history of allergic reactions to NSAIDs, asthma attacks, or those undergoing heart bypass surgery should avoid NSAIDs.
What increases the chances of getting a gastric ulcer when I am already taking Doloforce 40mg Injection?
The risk of gastric ulcers increases with corticosteroids, anticoagulants, long-term use, alcohol, smoking, and older age.
Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilmans: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 989-90
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1127-28
Central Drugs Standard Control Organisation (CDSCO) (02 Apr. 2019)
Piroxicam (06 Apr. 2024)
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