Rosiglitazone

Uses

Rosiglitazone is used in the treatment of type 2 diabetes mellitus.

How it Works

How Rosiglitazone works Rosiglitazone is an anti-diabetic medication that increases the body's sensitivity to insulin, a natural substance that helps regulate blood sugar levels.

Side Effects

Common side effects of Rosiglitazone include headache, back pain, edema (swelling), sinus inflammation, upper respiratory tract infection, liver injury, increased blood glucose levels, fatigue, diarrhea, and anemia (low number of red blood cells).

Expert Advice

Rosiglitazone has been withdrawn from the market due to an increased risk of heart attack and heart-related deaths.
Rosiglitazone aids in controlling blood sugar levels and preventing long-term complications.
Full effects may be observed after several weeks of initiating Rosiglitazone therapy.
Continue taking it as prescribed by your doctor.
Possible side effects include:
- Weight gain
- Headache
- Swelling due to fluid retention
Notify your doctor if you experience:
- Shortness of breath
- Heart problems
- Any abnormal swelling
May not be suitable for patients with a history of:
- Heart failure
- Bladder cancer
Continue to exercise regularly, maintain a healthy diet, and take your other diabetes medications alongside Rosiglitazone.
Take it only as per the dose and duration recommended by your doctor.
Regularly monitor your blood sugar levels while taking this medication.
Your doctor may also monitor your liver function.
Inform your doctor if you notice symptoms such as:
- Abdominal pain
- Yellowing of the eyes
- Loss of appetite

Other Combinations

Gliclazide + Metformin + Rosiglitazone

Gliclazide + Rosiglitazone

Glibenclamide + Metformin + Rosiglitazone

Glimepiride + Metformin + Rosiglitazone

Glimepiride + Rosiglitazone

Metformin + Rosiglitazone

Frequently asked questions

How should Rosiglitazone be used?

Rosiglitazone is an anti-diabetic medication that should be used alongside a proper diet and exercise program to manage high blood sugar in type 2 diabetes patients. It acts as an insulin sensitizer, reducing insulin resistance.

How does Rosiglitazone contribute to heart failure?

Rosiglitazone can cause fluid retention and edema, leading to fluid overload in the body, which may precipitate heart failure, especially in individuals at risk.

Is Rosiglitazone effective for treating depression?

According to a study, Rosiglitazone, either alone or as an adjunct to conventional treatments, may provide clinical benefits for patients with major depression.

Can Rosiglitazone be used with glimepiride in diabetes?

Yes, when Rosiglitazone is added to Glimepiride in diabetes mellitus patients, it significantly reduces plasma lipid levels and improves blood glucose control by decreasing insulin resistance.

What is the mechanism behind Rosiglitazone-induced edema?

Rosiglitazone increases capillary permeability, facilitating fluid movement across membranes, leading to accumulation and edema. Additionally, it enhances sodium and water reabsorption in the kidneys, contributing to edema.

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