Gliclazide + Metformin + Rosiglitazone
Uses
Gliclazide, Metformin, and Rosiglitazone are used in the treatment of type 2 diabetes mellitus.
How it Works
How Gliclazide, Metformin, and Rosiglitazone Work Gliclazide, Metformin, and Rosiglitazone is a combination of three antidiabetic medications: Gliclazide, Metformin, and Rosiglitazone. They work through different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Gliclazide is a sulfonylurea that increases the amount of insulin released by the pancreas to lower blood glucose levels. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione that further increases insulin sensitivity.
Side Effects
Common side effects of Gliclazide, Metformin, and Rosiglitazone include hypoglycemia (low blood glucose level), nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), weight gain, blurred vision, bone fractures, and respiratory tract infections.
Expert Advice
- Take it with food to reduce the likelihood of experiencing an upset stomach.
- It may cause hypoglycemia (low blood sugar levels) when used in conjunction with other antidiabetic medications, alcohol, or if you delay or miss a meal.
- Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms, such as:
- Cold sweats
- Cool, pale skin
- Tremors
- Anxiety
- Your doctor may monitor your liver function regularly.
- Inform your doctor if you develop symptoms such as:
- Abdominal pain
- Loss of appetite
- Yellowing of the eyes or skin (jaundice)
