Glibenclamide + Metformin + Rosiglitazone

Uses

Glibenclamide, Metformin, and Rosiglitazone are used in the treatment of type 2 diabetes mellitus.

How it Works

How Glibenclamide, Metformin, and Rosiglitazone work Glibenclamide, Metformin, and Rosiglitazone is a combination of three antidiabetic medications: Glibenclamide, Metformin, and Rosiglitazone. They work through different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glibenclamide is a sulfonylurea that increases the amount of insulin released by the pancreas to lower blood glucose levels. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin. Rosiglitazone is a thiazolidinedione that further enhances insulin sensitivity.

Side Effects

Common side effects of Glibenclamide, Metformin, and Rosiglitazone include hypoglycemia (low blood glucose level), nausea, changes in taste, diarrhea, stomach pain, headache, edema (swelling), weight gain, blurred vision, bone fractures, and respiratory tract infections.

Expert Advice

Take it with food to reduce the likelihood of an upset stomach.
It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medications, alcohol, or if you delay or miss a meal.
Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms, such as: