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Nirmatrelvir + Ritonavir

Uses

Nirmatrelvir + Ritonavir Uses Nirmatrelvir and Ritonavir are used in the treatment of coronavirus disease (COVID-19).

How it Works

How Nirmatrelvir + Ritonavir works Nirmatrelvir + Ritonavir is a combination of two drugs: nirmatrelvir, a SARS-CoV-2-3CL protease inhibitor, and ritonavir, an HIV antiretroviral. Nirmatrelvir inhibits the action of the SARS-CoV-2-3CL protease enzyme, which is essential for the virus's replication. Meanwhile, ritonavir prevents the breakdown of nirmatrelvir.

Side Effects

Common side effects of Nirmatrelvir and Ritonavir include taste changes, diarrhea, vomiting, high blood pressure, and muscle pain.

Expert Advice

  • Do not administer Nirmatrelvir + Ritonavir to children under 12 years of age or those weighing less than 40 kg.
  • Seek immediate medical attention if you observe signs of allergic reactions, such as:
    • Rash
    • Difficulty swallowing or breathing
    • Swelling of the eyelids, lips, face, throat, or tongue
  • Inform your doctor if you have liver or kidney disease prior to starting the treatment.
  • It is advisable to use non-hormonal contraceptive methods during the 5 days of Nirmatrelvir + Ritonavir treatment and for one menstrual cycle after discontinuing the drug.
  • Do not discontinue Nirmatrelvir + Ritonavir without consulting your doctor first, as it helps protect you from severe illness due to COVID-19.
  • Even after treatment, continue to practice COVID-appropriate behaviors, including:
    • Wearing a mask
    • Maintaining social distance
    • Frequent handwashing

Other Combinations

Atazanavir + Emtricitabine + Ritonavir + Tenofovir disoproxil fumarate

Atazanavir + Lamivudine + Ritonavir + Tenofovir disoproxil fumarate

Darunavir + Ritonavir

Lopinavir + Ritonavir

Atazanavir + Ritonavir

Related Medications

Frequently asked questions

If you miss a dose within 8 hours, take it as soon as possible and continue your regular schedule. If it's been over 8 hours, skip the missed dose and take the next scheduled dose at the usual time. Do not double the dose.
Yes, Nirmatrelvir+Ritonavir contains lactose, a type of sugar. Inform your doctor if you have an allergy to lactose or sugar before taking this medication.
No, Nirmatrelvir+Ritonavir is not considered safe for children, as its effects have not been studied in individuals under 18 years of age.
Yes, Nirmatrelvir+Ritonavir may reduce the effectiveness of HIV treatments. Use it only if prescribed by a doctor; self-medication is not advised.
Yes, some patients may experience allergic reactions, including rashes or hives. Seek immediate medical attention if you notice skin reactions, difficulty breathing, or swelling.
No, avoid other medications while on Nirmatrelvir+Ritonavir unless prescribed by your doctor, as interactions may occur. Consult your doctor before taking any additional medicine.
Yes, complete the full 5-day course as prescribed. Skipping doses can hinder viral clearance and worsen your condition. Maintain isolation and follow preventive measures to reduce viral transmission.
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