Yondelis Injection is used in the treatment of some kinds of cancers. It is used in patients with advanced soft tissue sarcoma when previous medicines have been unsuccessful. It is also used with other medicines as part of combination therapy to treat ovarian cancer that has come back. Yondelis Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include headache, fatigue, vomiting, weakness and increased liver enzyme. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and kidney. Generally, avoid alcohol consumption while on treatment. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
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Yondelis Injection is used in the treatment of some kinds of cancers. It is used in patients with advanced soft tissue sarcoma when previous medicines have been unsuccessful. It is also used with other medicines as part of combination therapy to treat ovarian cancer that has come back. Yondelis Injection is given as an injection under the medical supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include headache, fatigue, vomiting, weakness and increased liver enzyme. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver and kidney. Generally, avoid alcohol consumption while on treatment. Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using.This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Soft tissue sarcoma
In Soft tissue sarcoma Soft tissue sarcoma is a type of sarcoma that develops in tissues such as bone and muscles. Yondelis Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Follow your doctor?s instructions carefully and let your doctor know if any of the side effects bother you.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Fatigue, Vomiting, Weakness, Nausea, Increased liver enzymes, Low blood platelets, Increased creatine phosphokinase (CPK) level in blood, Decreased white blood cell count (neutrophils), Decreased appetite, Constipation']
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Trabectedin belongs to class of drugs called alkylating agents. It works by sticking to the DNA in cells and damaging it. This stops the cancer cells growing and multiplying. .
Alcohol
Unsafe: Avoid consuming alcohol with Yondelis Injection as it is deemed unsafe.
Pregnancy
Seek medical advice from your doctor: Information regarding the use of Yondelis Injection during pregnancy is not available. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Information regarding the use of Yondelis Injection during breastfeeding is not available. Doctor consultation is advised.
Driving
Not Safe: Yondelis Injection may cause side effects which could affect your ability to drive. Yondelis Injection may make you feel tired and experience a loss of strength which may affect your ability to drive.
Kidney
Caution Advised: Yondelis Injection should be used with caution in patients with kidney disease. Dose adjustment of Yondelis Injection may be needed. Doctor consultation is advised.
Liver
Caution Advised: Yondelis Injection should be used with caution in patients with liver disease. Dose adjustment of Yondelis Injection may be needed. Doctor consultation is advised.
Store in a cool and dry place, and keep the temperature below 30�C
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