V Nyle MF 500mg/0.3mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. V Nyle MF 500mg/0.3mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes. This medicine may cause side effects like nausea, taste change, loss of appetite, flatulence, stomach pain, diarrhea, and skin rash. However, these are temporary and usually subside on their own. If these do not resolve or worry you, please consult your doctor. Your doctor might suggest ways of dealing with your side effects or treating them if they are bothersome. You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 24-06-2025
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V Nyle MF 500mg/0.3mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. V Nyle MF 500mg/0.3mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels. Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes. This medicine may cause side effects like nausea, taste change, loss of appetite, flatulence, stomach pain, diarrhea, and skin rash. However, these are temporary and usually subside on their own. If these do not resolve or worry you, please consult your doctor. Your doctor might suggest ways of dealing with your side effects or treating them if they are bothersome. You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.
Treatment of Type 2 diabetes mellitus
In Treatment of Type 2 diabetes mellitus V Nyle MF 500mg/0.3mg Tablet is a medicine that helps to control high blood glucose (sugar) levels. It helps to slow down the breaking down of food in our intestine to simple glucose (sugar), thereby decreasing the rise in blood glucose levels after meals. It also helps get rid of extra glucose from your body through urine. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level, you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems and loss of limbs. V Nyle MF 500mg/0.3mg Tablet will reduce the risk of dying from cardiovascular disease if you have type 2 diabetes and already have cardiovascular disease. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed because it is protecting your future health.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Diarrhea, Bloating, Abdominal pain, Vomiting, Decreased appetite']
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. V Nyle MF 500mg/0.3mg Tablet is to be taken with food.
V Nyle MF 500mg/0.3mg Tablet is a combination of two antidiabetic medicines: Metformin and voglibose. Metformin lowers the production and absorption of sugar in your body and allows better use of existing insulin. Voglibose inhibits the intestinal enzymes that cause breakdown of complex sugars into simple sugars such as glucose. This prevents blood glucose from rising very high after meals.
Alcohol
Unsafe: Avoid consuming alcohol with V Nyle MF 500mg/0.3mg Tablet as it is deemed unsafe.
Pregnancy
Seek medical advice from your doctor: V Nyle MF 500mg/0.3mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: V Nyle MF 500mg/0.3mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE - V Nyle MF 500mg/0.3mg Tablet does not usually affect your ability to drive. However, patients should be alerted to the risk of hypoglycemia when it is used in combination with other antidiabetic agents such as sulfonylureas, insulin, and repaglinide.
Kidney
Caution Advised: V Nyle MF 500mg/0.3mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of V Nyle MF 500mg/0.3mg Tablet may be needed. Doctor consultation is advised. Use of V Nyle MF 500mg/0.3mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
Seek medical advice from your doctor: There is limited information available on the use of V Nyle MF 500mg/0.3mg Tablet in patients with liver disease. Doctor consultation is advised.
If a dose of V Nyle MF 500mg/0.3mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
Take it with food to lower your chance of having an upset stomach. It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.� Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor, and anxious feeling. Monitor your blood sugar level regularly while taking this medicine. Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting or stomach pain as V Nyle MF 500mg/0.3mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
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