Systen 3.2mg Transdermal Patch is a female sex hormone (estrogen). This is a hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness and itching), estrogen deficiency (hypoestrogenism), and thinning of bones (osteoporosis).Systen 3.2mg Transdermal Patch should be used as per the provided instructions by the doctor. Even if your symptoms improve, you should continue the treatment as it has been prescribed. The course of the treatment must be completed for better efficacy.The most common side effects of this medicine include breast discomfort, abnormal menstrual bleeding, application site reactions, headache, nausea, abdominal pain, and abdominal distension. If any of these side effects bother you, consult your doctor. Also, tell your doctor if you notice bleeding from your vagina or develop breast lumps.Before using this medicine you should tell your doctor if you have unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. Once you have started using this medicine you should have regular check-ups to discuss the benefits of your treatment. It should not interact with any other medicines but it is not usually recommended during pregnancy or breastfeeding.
Written by: Radhika B Shiraguppi, B. Pharma
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 30-04-2025
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Systen 3.2mg Transdermal Patch is a female sex hormone (estrogen). This is a hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness and itching), estrogen deficiency (hypoestrogenism), and thinning of bones (osteoporosis).Systen 3.2mg Transdermal Patch should be used as per the provided instructions by the doctor. Even if your symptoms improve, you should continue the treatment as it has been prescribed. The course of the treatment must be completed for better efficacy.The most common side effects of this medicine include breast discomfort, abnormal menstrual bleeding, application site reactions, headache, nausea, abdominal pain, and abdominal distension. If any of these side effects bother you, consult your doctor. Also, tell your doctor if you notice bleeding from your vagina or develop breast lumps.Before using this medicine you should tell your doctor if you have unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. Once you have started using this medicine you should have regular check-ups to discuss the benefits of your treatment. It should not interact with any other medicines but it is not usually recommended during pregnancy or breastfeeding.
Hormone replacement therapy
In Hormone replacement therapy : Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Systen Transdermal Patch The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them Common side effects of Systen Application site reactions (burning, irritation, itching and redness)Breast discomfort Abnormal menstrual bleeding Headache Nausea Abdominal pain Abdominal distension
How to use Systen Transdermal Patch Use this medicine in dose and duration as advised by your doctor. Check the label before use. Make sure the skin is clean and dry. Remove the protective liner of the patch. Do not touch the sticky side. With sticky side down, place the patch evenly onto the skin.
How Systen Transdermal Patch works Systen 3.2mg Transdermal Patch contains a medication called estrogen (female sex hormone). It works by replacing estrogen that is normally produced by the body.
Alcohol
No interaction has been found or established.
Pregnancy
Systen 3.2mg Transdermal Patch is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
Systen 3.2mg Transdermal Patch is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
No interaction found/established
Kidney
Systen 3.2mg Transdermal Patch should be used with caution in patients with kidney disease. Dose adjustment of Systen 3.2mg Transdermal Patch may be needed. Doctor consultation is advised.
Liver
Systen 3.2mg Transdermal Patch should be used with caution in patients with liver disease. Dose adjustment of Systen 3.2mg Transdermal Patch may be needed. Doctor consultation is advised.Use of Systen 3.2mg Transdermal Patch is not recommended in patients who previously had liver disease and the liver function tests are still not normal.
Store in a cool and dry place, and keep the temperature below 30�C
You have been prescribed Systen 3.2mg Transdermal Patch as a part of hormone replacement therapy to relieve symptoms of menopause. It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures. It has a lower risk of side effects since lower amount of estrogen is used in patches. Apply it once a week, to a clean, dry, unbroken, non-irritated area of skin below the waist, on the lower back or buttocks. Do not expose it to sunlight. Replace it every 7 days, and apply on a different area of skin to prevent skin irritation. Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Systen 3.2mg Transdermal Patch. Stop using this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.
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