Matiz-I Granules is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.Matiz-I Granules is taken without food, following the dosage and duration recommended by your doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.The most common side effects are skin rash and bloating. These are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.Lifestyle modifications like having fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake and regular exercise can help you to get better results. Before taking it, you should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Varinderjeet Kaur, MBBS
Last updated on: 24-06-2025
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Matiz-I Granules is used to treat irritable bowel syndrome (symptoms include abdominal pain, cramping, bloating, and diarrhea or constipation). It prevents the sudden spasm of muscles to relieve stomach pain and cramps. It also promotes easy passage of gas to reduce stomach discomfort.Matiz-I Granules is taken without food, following the dosage and duration recommended by your doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.The most common side effects are skin rash and bloating. These are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects.Lifestyle modifications like having fiber-rich diet, avoiding foods that trigger your symptoms, increasing fluid intake and regular exercise can help you to get better results. Before taking it, you should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Irritable bowel syndrome
In Irritable bowel syndrome : Irritable bowel syndrome is a chronic (long-term) inflammatory disease of the large intestine (colon) that usually needs long term management. This can lead to bleeding, frequent diarrhea, bloating, flatulence, cramps and stomach pain. Matiz-I Granules relaxes the muscles in your stomach and gut (intestine) and relieves these symptoms effectively. Usually, it is used along with other medicines for management of your condition. Continue taking it for as long as the doctor may advise you to. You need to take this medicine regularly to get the most out of it. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.
Side effects of Matiz-I Granules The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Matiz-ISkin rash Bloating
How to use Matiz-I Granules Follow your doctor's guidance regarding the dose and duration of this medication. Check the label for directions before use. Empty the granules in a glass of water/milk, stir it and consume immediately. Matiz-I Granules is to be taken empty stomach.
How Matiz-I Granules works Matiz-I Granules is a combination of two medicines: Mebeverine and Ispaghula which treat irritable bowel syndrome.
Alcohol
Safe: No harmful side effects are associated with consuming alcohol alongside Matiz-I Granules
Pregnancy
Matiz-I Granules is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Information regarding the use of Matiz-I Granules during breastfeeding is not available. Doctor consultation is advised.
Driving
Matiz-I Granules does not usually affect your ability to drive.
Kidney
Matiz-I Granules is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Doctor consultation is advised.
Liver
Matiz-I Granules is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Matiz-I Granules may not be needed in these patients. Please consult your doctor.
If a dose of Matiz-I Granules is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
Matiz-I Granules helps relieve symptoms of� irritable bowel syndrome such as abdominal pain, bloating, and diarrhea. Take it half an hour before food. Do not take it just before going to bed. Stir it in a glass of cold water and drink immediately. Drink plenty of liquids through the day. Flatulence and bloating may occur during the first few days of taking this medicine. Inform your doctor if this does not go away. Inform your doctor if your symptoms do not improve after two weeks of using this medicine.
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