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Lefonza 500mg Tablet 10s

Lefonza 500mg Tablet 10s

Plena Remedies

Strip of 10 tablets

76

7.6 / Unit
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Our Recommendation

L Quin 500mg Tablet 10s

L Quin 500mg Tablet 10s

Cipla Ltd.
Strip of 10 tablets

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Treatment of Bacterial infections

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More About Lefonza 500mg Tablet 10s

Short Description
Long Description
How to use
Benefits
Side Effects
How to Consume
SafetyAdvice
Quick Tips (Expert Guidance)
Storage
Drug-Food Interactions
Interactions with Other Drugs
Drug-Disease Interactions
Daily Dose
Overdose
What If You Forget to take Lefonza 500mg Tablet 10s?
FAQs
References
Fact Box

Quick Summary

Lefonza 500mg Tablet 10s is a broad-spectrum fluoroquinolone antibiotic used to treat a wide variety of bacterial infections. It contains the active ingredient Levofloxacin, which is effective against bacteria that cause infections in the lungs, sinuses, urinary tract, skin, and prostate. By inhibiting the essential enzymes required for bacterial DNA replication, Lefonza 500mg Tablet 10s stops the growth of bacteria and eliminates the infection. It is commonly prescribed for conditions such as pneumonia, acute bacterial sinusitis, and complicated urinary tract infections.

Detailed Description

Lefonza 500mg Tablet 10s contains levofloxacin, a broad-spectrum antibiotic from the fluoroquinolone class, used for the treatment of a wide range of bacterial infections in adults. It is prescribed when infections are caused by susceptible bacteria and require effective systemic antibacterial therapy.

Levofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that play a critical role in bacterial DNA replication, transcription, repair, and recombination. By disrupting these essential processes, Lefonza 500mg Tablet 10s prevents bacterial growth and leads to the elimination of the infection.

Lefonza 500mg Tablet 10s is commonly indicated for respiratory tract infections such as community-acquired pneumonia, acute bacterial sinusitis, and acute exacerbations of chronic bronchitis. It is also used in the treatment of urinary tract infections, including complicated infections and pyelonephritis, as well as skin and soft tissue infections and certain gastrointestinal infections. In specific circumstances, levofloxacin may be prescribed for post-exposure prophylaxis of inhalational anthrax or for the treatment of plague, highlighting its broad antibacterial activity.

By directly targeting bacterial DNA replication, Lefonza 500mg Tablet 10s helps control infection, supports faster recovery, and reduces the risk of complications associated with untreated bacterial infections. To ensure safety and optimal effectiveness, it is important to follow the prescribed dosage and complete the full course of treatment as advised by a healthcare provider.

Uses of Lefonza 500mg Tablet 10s

Lefonza 500mg Tablet 10s is indicated for the treatment of bacterial infections in adults, including:

Respiratory Tract Infections:

Such as community-acquired pneumonia, acute bacterial sinusitis, and acute exacerbations of chronic bronchitis.

Urinary Tract Infections (UTIs):

Including complicated UTIs and acute pyelonephritis.

Skin and Soft Tissue Infections:

Effective against cellulitis, abscesses, and wound infections caused by susceptible bacteria.

Gastrointestinal Infections:

Such as infectious diarrhoea caused by certain bacterial strains.

Prophylaxis and Treatment of Anthrax:

Used for post-exposure prophylaxis and treatment of inhalational anthrax.

Plague (Yersinia pestis):

May be prescribed for treatment or prophylaxis in specific cases.

Benefits of Lefonza 500mg Tablet 10s

Potent Bactericidal Action:

Rapidly kills bacteria to resolve symptoms quickly.

Broad Spectrum:

Effective against a diverse range of pathogens, including many that are resistant to other antibiotic classes like penicillins or macrolides.

Excellent Tissue Reach:

Effectively reaches high concentrations in the lungs, skin, and urinary system.

Convenient Administration:

Its high absorption rate allows for effective treatment with simple daily dosing.

Versatile Treatment:

Can be used for a variety of different organ-system infections.

Side Effects of Lefonza 500mg Tablet 10s

When taken as directed, Lefonza 500mg Tablet 10s is generally safe. Side effects are usually rare, mild, and temporary.

Common Side Effects (Mild and temporary):

  • Nausea or diarrhoea
  • Headache
  • Dizziness
  • Difficulty sleeping (insomnia)
  • Constipation or abdominal pain

Serious Side Effects (Stop taking the medicine and seek urgent medical attention if you experience):

  • Tendon Issues: Pain, swelling, or rupture of tendons (especially the Achilles tendon).
  • Nerve Damage (Peripheral Neuropathy): Numbness, tingling, or burning pain in the hands or feet.
  • CNS Effects: Seizures, tremors, hallucinations, or severe confusion.
  • Severe Allergic Reactions: Face swelling, skin rash, or difficulty breathing.
  • C. diff-associated Diarrhoea: Severe, persistent watery or bloody stools.

Directions for Use

  • Administration: Swallow the medicine whole with a full glass of water. It can be taken with or without food.
  • Consistency: Take the dose at the same time every day to keep a steady amount of medicine in your body.
  • Hydration: Drink plenty of water during treatment to prevent the formation of crystals in the urine.
  • Complete the Course: Always finish the entire duration of treatment prescribed by your doctor, even if you feel better after a few days. Stopping early can lead to the return of the infection and antibiotic resistance.

Safety Advice for Lefonza 500mg Tablet 10s

PREGNANCY

CONSULT YOUR DOCTOR.

Use is generally avoided during pregnancy unless the potential benefit justifies the potential risk to the fetus.

Read More

BREASTFEEDING

CAUTION.

Levofloxacin is excreted in breast milk. Consult your doctor to discuss whether to discontinue nursing or the drug.

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DRIVING

MODERATE.

May cause dizziness, lightheadedness, or vision problems. Do not drive or operate machinery until you know how the medicine affects you.

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LIVER

NO INTERACTION.

Generally safe for the liver as it is primarily cleared by the kidneys, but consult your doctor if you have a history of liver disease.

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KIDNEY

CAUTION.

Dose adjustment is necessary for patients with reduced kidney function as the drug is mainly excreted through urine.

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ALCOHOL

MODERATE.

Alcohol can worsen dizziness and stomach-related side effects. It is best to avoid alcohol during treatment.

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FOOD

NO INTERACTION.

Can be taken with or without food. Avoid taking it simultaneously with dairy or fortified juices, which can limit absorption.

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LIFESTYLE

CAUTION.

Avoid excessive sunlight or UV exposure (tanning beds) as the medicine increases the risk of severe sunburn (photosensitivity).

Read More

Quick Tips for Lefonza 500mg Tablet 10s

  • Complete the Course: Always finish the full prescribed course, even if symptoms improve early. Stopping too soon may allow bacteria to survive and cause reinfection or resistance.
  • Consistent Timing: Take the medicine at the same time each day to maintain steady antibiotic levels in the body.
  • Hydration: Drink plenty of water during treatment to support kidney function and reduce the risk of crystalluria (crystals forming in urie).
  • Tendon Safety: Stop the medicine immediately and seek medical advice if you experience tendon pain, swelling, or rupture. Risk is higher in older adults and those on corticosteroids.
  • Sun Protection: Levofloxacin can increase sensitivity to sunlight. Use sunscreen and avoid tanning beds to prevent sunburn.
  • Avoid Antacids and Supplements: Do not take antacids, iron, or zinc supplements within 2 hours before or after Levofloxacin, as they reduce absorption

Storage Advice

Store in a cool, dry place away from direct sunlight. Keep the container tightly closed and out of the reach of children. Store at a temperature below 30°C.

Drug-Food Interaction

  • Dairy Products: Calcium-rich foods like milk or yoghurt can bind to Levofloxacin and prevent its absorption. Take the medicine 2 hours before or after consuming dairy.
  • Caffeine: Levofloxacin can slow down the metabolism of caffeine, leading to increased nervousness or heart palpitations.

Interactions with Other Drugs

  • Antacids/Iron/Zinc: These interfere with absorption. Take Lefonza 500mg Tablet 10s 2 hours before or after these products.
  • Warfarin: May enhance the effect of blood thinners, increasing the risk of bleeding.
  • NSAIDS: Combining with certain painkillers (like ibuprofen) may increase the risk of CNS stimulation and seizures.

Drug-Disease Interactions

  • Myasthenia Gravis: May worsen muscle weakness and breathing problems; use is usually avoided.
  • Epilepsy/Seizures: May lower the seizure threshold and trigger convulsions.
  • Heart Rhythm Disorders: May cause QT prolongation (a heart rhythm issue).
  • Diabetes: May cause significant changes in blood sugar (hypoglycemia or hyperglycemia).

Daily Dose

The dosage is determined by the type and severity of the infection. It is typically administered as a single daily dose for a period ranging from 3 to 14 days (or longer for specific conditions like prostatitis).

Overdose

Overdose may cause confusion, dizziness, seizures, and gastrointestinal upset. Action Required: Contact emergency medical services immediately if an overdose is suspected.

What If You Forget to take Lefonza 500mg Tablet 10s?

Take the missed dose as soon as you remember. If the next dose is near, skip the missed one. Do not take two doses at once to compensate.

Frequently asked questions

Yes, both medicines have the same salt composition, dosage, and effectiveness. They work the same way in your body. The only difference is the brand — and Lquin option is much more affordable without compromising on quality
Lefonza 500mg Tablet 10s is prescribed to treat a wide range of bacterial infections, including respiratory tract infections (such as pneumonia, bronchitis, and sinusitis), urinary tract infections, skin and soft tissue infections, and certain gastrointestinal infections. It may also be used in special cases like anthrax exposure or plague treatment.
Levofloxacin belongs to the fluoroquinolone class of antibiotics. It works by inhibiting bacterial enzymes (DNA gyrase and topoisomerase IV) that are essential for DNA replication, transcription, and repair. This disruption prevents bacteria from multiplying and leads to their death.
Take Lefonza 500mg Tablet 10s exactly as prescribed by your doctor, usually once daily. It can be taken with or without food, but should always be swallowed whole with water. Consistent timing each day helps maintain effective drug levels in the body.
Yes. Common side effects include nausea, diarrhoea, headache, dizziness, or trouble sleeping. These are usually mild and temporary. Rare but serious side effects include tendon rupture, nerve damage, seizures, or severe allergic reactions.
No. Levofloxacin does not lower blood sugar directly. However, it may interact with certain diabetes medications, so patients with diabetes should monitor their blood sugar closely while on treatment.
Yes. Rare but serious risks include tendon rupture (especially in older adults or those taking corticosteroids), peripheral neuropathy (nerve damage), central nervous system effects (such as seizures or mood changes), and severe allergic reactions. Seek urgent medical care if these occur.
Yes. Your doctor may monitor kidney function, liver function, and overall treatment response, especially if you are on long-term therapy or have underlying health conditions.
Alcohol does not directly interact with Levofloxacin, but excessive intake may worsen side effects such as dizziness, stomach upset, or reduced alertness. It is best to limit alcohol during treatment.
No. Levofloxacin does not typically affect body weight.
Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double up doses.
Yes, but dose adjustments may be required. Since Levofloxacin is eliminated through the kidneys, patients with impaired kidney function should be closely monitored to avoid drug accumulation.
Not usually. However, always inform your doctor about all medications you are taking before surgery or diagnostic procedures, as adjustments may be necessary depending on your condition.
Levofloxacin is generally not recommended during pregnancy or breastfeeding due to potential risks to the baby’s developing joints and cartilage. Use only if the benefits clearly outweigh the risks, as determined by a doctor.
Yes. Antacids, iron supplements, corticosteroids, NSAIDs, and certain heart medications may interact with Levofloxacin, reducing its effectiveness or increasing side effects. Always inform your doctor about all medicines, supplements, or herbal products you are taking.
Levofloxacin is usually prescribed for short courses (5–14 days). Long-term use is rare and may increase the risk of serious side effects such as tendon rupture or nerve damage. It should only be used long-term under strict medical supervision.

References

  • https://www.ncbi.nlm.nih.gov/books/NBK545180/

  • https://go.drugbank.com/drugs/DB01137

  • https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021721s020_020635s57_020634s52_lbl.pdf

  • https://pubchem.ncbi.nlm.nih.gov/compound/Levofloxacin

Fact Box

Therapeutic Class

Anti-Infective / Antibiotic

Action Class

Fluoroquinolone (DNA Gyrase Inhibitor)

Chemical Class

Quinolone Derivative

Habit Forming

No

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Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.

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