Endobloc T 5/20mg Combipack Tablet 20s
Endobloc T Combipack is a combination medicine used in the treatment of pulmonary arterial hypertension (PAH). It works by relaxing the blood vessels inside the lungs. Endobloc T Combipack can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. The most common side effects of this medicine include peripheral edema, headache, nasal congestion, cough, anemia, indigestion, and bronchitis. These are usually mild but let your doctor know if they bother you or last more than a few days. It may cause anemia (low number of red blood cells), hence you may be asked for a blood test to check for anemia. You must consult your doctor if the erection persists for more than 4 hours after sexual intercourse while taking this medicine. Before using it, you should tell your doctor if you have any heart problems or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Generally, it is advised to avoid alcohol while taking this medicine.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 31-05-2025
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More About Endobloc T 5/20mg Combipack Tablet 20s
Quick Summary
Endobloc T Combipack is a combination medicine used in the treatment of pulmonary arterial hypertension (PAH). It works by relaxing the blood vessels inside the lungs. Endobloc T Combipack can be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. The most common side effects of this medicine include peripheral edema, headache, nasal congestion, cough, anemia, indigestion, and bronchitis. These are usually mild but let your doctor know if they bother you or last more than a few days. It may cause anemia (low number of red blood cells), hence you may be asked for a blood test to check for anemia. You must consult your doctor if the erection persists for more than 4 hours after sexual intercourse while taking this medicine. Before using it, you should tell your doctor if you have any heart problems or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Generally, it is advised to avoid alcohol while taking this medicine.
Benefits of Endobloc T 5/20mg Combipack Tablet 20s
Treatment of Pulmonary arterial hypertension (PAH)
In Treatment of Pulmonary arterial hypertension (PAH) Pulmonary arterial hypertension can cause shortness of breath, tiredness, dizziness, chest pain and swelling in your ankles and legs. It is caused by thickening of walls of the arteries that supply your lungs making it hard for blood to get through. Endobloc T Combipack relaxes the blood vessels and can help lower the blood pressure in the arteries of your lungs. You will be able to carry out your daily activities more easily and feel less tired or dizzy.
Side Effects of Endobloc T 5/20mg Combipack Tablet 20s
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Headache, Nasal congestion (stuffy nose), Cough, Anemia (low number of red blood cells), Indigestion, Bronchitis (inflammation of the airways)']
Directions for Use
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Endobloc T Combipack can be taken it with or without food, although it's advisable to take it consistently at the same time.
How it works
Endobloc T Combipack is a combination of two medicines: Ambrisentan and Tadalafil which treat pulmonary arterial hypertension (high blood pressure in the lungs). Ambrisentan is an endothelin receptor antagonist and tadalafil is a PDE-5 inhibitor. They work together to lower the blood pressure inside the lungs vessels by relaxing them. This improves your ability to do physical activity.
Alcohol
Consult your Doctor: Please consult your doctor regarding the safety of consuming alcohol with Endobloc T Combipack . Experts have not found evidence of alcohol impairing the effectiveness of the medicine.
Pregnancy
Seek medical advice from your doctor: Endobloc T Combipack is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Information regarding the use of Endobloc T Combipack during breastfeeding is not available. Doctor consultation is advised.
Driving
Caution Advised: Endobloc T Combipack may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.
Kidney
Safe when prescribed by an expert: Endobloc T Combipack is safe to use in patients with kidney disease. No dose adjustment of Endobloc T Combipack is recommended.
Liver
Not Safe: Endobloc T Combipack is probably unsafe to use in patients with liver disease and should be avoided. Doctor consultation is advised.
What If You Forget to take Endobloc T 5/20mg Combipack Tablet 20s?
If a dose of Endobloc T Combipack is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Storage Advice
Store in a cool and dry place, and keep the temperature below 30�C
Quick Tips for Endobloc T 5/20mg Combipack Tablet 20s
Take it at same time every day to maintain the consistent level of drug in the body. Do not skip any doses and finish the full course of treatment even if you feel better. Your doctor may ask you to get routine blood tests done to check for anemia and to assess the functioning of your liver. Do not drive or do anything requiring concentration until you know how Endobloc T Combipack affects you. Females with reproductive potential should use a reliable form of birth control while using and 1 month after stopping medicine as it is toxic to an unborn baby. Notify your doctor if you are pregnant or planning to conceive or breastfeeding.
Manufacturer Address
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
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