Datisole 500mg Tablet SR is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the liver, stomach, intestines, vagina, brain, heart, lungs, and skin.Datisole 500mg Tablet SR is also used in the treatment of dental infections, leg ulcers, and pressure sores. This medicine should be taken with food, at the same time each day to get the most benefit. The amount you are advised will depend on what you are being treated for and how bad it is, but you should take this antibiotic exactly as prescribed by your doctor. Your symptoms may get better after a short time but do not stop taking it until you have finished a full course of treatment, even if you feel well. If you stop taking it early, some bacteria may survive, and the infection may come back. Do not drink any alcohol while taking this medicine and for some days after stopping it. Otherwise, you may get unpleasant side effects like nausea, vomiting, and stomach pain.The most common side effects of this medicine are headache, dryness in the mouth, nausea, and a slight metallic taste in the mouth. These are usually mild but let your doctor know if they bother you or last more than a few days. You can try using sugarless candies or lozenges to overcome any dryness or metallic taste in the mouth.Before using this medicine, inform your doctor if you are allergic to any medicine or have any kidney or liver problems or any disease of the nervous system. This medicine should not be taken if you are pregnant or breastfeeding unless it is absolutely necessary and prescribed by your doctor.
Written by: Syeda Jigni Mehraj, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 24-06-2025
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Datisole 500mg Tablet SR is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the liver, stomach, intestines, vagina, brain, heart, lungs, and skin.Datisole 500mg Tablet SR is also used in the treatment of dental infections, leg ulcers, and pressure sores. This medicine should be taken with food, at the same time each day to get the most benefit. The amount you are advised will depend on what you are being treated for and how bad it is, but you should take this antibiotic exactly as prescribed by your doctor. Your symptoms may get better after a short time but do not stop taking it until you have finished a full course of treatment, even if you feel well. If you stop taking it early, some bacteria may survive, and the infection may come back. Do not drink any alcohol while taking this medicine and for some days after stopping it. Otherwise, you may get unpleasant side effects like nausea, vomiting, and stomach pain.The most common side effects of this medicine are headache, dryness in the mouth, nausea, and a slight metallic taste in the mouth. These are usually mild but let your doctor know if they bother you or last more than a few days. You can try using sugarless candies or lozenges to overcome any dryness or metallic taste in the mouth.Before using this medicine, inform your doctor if you are allergic to any medicine or have any kidney or liver problems or any disease of the nervous system. This medicine should not be taken if you are pregnant or breastfeeding unless it is absolutely necessary and prescribed by your doctor.
Bacterial infections / Parasitic infections
In Bacterial infections : Datisole 500mg Tablet SR is an antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the liver, stomach, intestines, vagina, brain, heart, lungs, bones, and skin. It works by stopping the growth of the bacteria causing the infection. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even if you feel better, to make sure that all bacteria are killed and do not become resistant.In Parasitic infections Datisole 500mg Tablet SR helps treat many parasitic infections. It works by killing and stopping the further growth of parasites causing the infection. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all parasites are killed and do not become resistant. show moreshow less
Side effects of Datisole Tablet SRThe majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Datisole Headache Dryness in mouth Nausea Metallic taste
How to use Datisole Tablet SRFollow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Datisole 500mg Tablet SR is to be taken with food.
How Datisole Tablet SR works Datisole 500mg Tablet SR is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.
Alcohol
Unsafe: It is unsafe to consume alcohol while taking Datisole 500mg Tablet SR , as it may lead to symptoms such as flushing, increased heart rate, nausea, thirst, chest pain, and low blood pressure, known as a Disulfiram reaction.
Pregnancy
Datisole 500mg Tablet SR may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Datisole 500mg Tablet SR should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.If a single dose of Datisole 500mg Tablet SR is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug.
Driving
Datisole 500mg Tablet SR may cause side effects which could affect your ability to drive.Datisole 500mg Tablet SR may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.
Kidney
Datisole 500mg Tablet SR is safe to use in patients with kidney disease. No dose adjustment of Datisole 500mg Tablet SR is recommended.
Liver
Datisole 500mg Tablet SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Datisole 500mg Tablet SR may not be needed in these patients. Please consult your doctor.
If a dose of Datisole 500mg Tablet SR is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Datisole 500mg Tablet SR treats infections caused by bacteria and parasites. It may also be used to prevent infections following surgery. Always take the complete course of treatment, as advised by your doctor, even if you feel better. It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth. Datisole 500mg Tablet SR used in a high dose or for a prolonged time increases the risk of side effects�such as nerve damage. Take it only as prescribed by your doctor. Do�not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache. Inform your doctor if you have� liver disease. Your dose may need to be adjusted in severe liver disease.
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