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Bempedoic acid

Uses

Bempedoic acid is used in the treatment of high cholesterol.

How it Works

How Bempedoic acid works Bempedoic acid functions by inhibiting an enzyme (adenosine triphosphate-citrate lyase) necessary for the production of "bad" cholesterol (low-density lipoprotein) in the liver, leading to reduced levels of "bad" cholesterol.

Side Effects

Common side effects of Bempedoic acid include pain in the extremities, anemia (low red blood cell count), increased liver enzymes, upper respiratory tract infection, muscle spasms, elevated uric acid levels in the blood, back pain, abdominal pain, and bronchitis (inflammation of the airways).

Expert Advice

  • Take Bempedoic acid after a meal or with a snack to minimize gastrointestinal issues.
  • Inform your doctor if you experience:
    • Fatigue
    • Muscle weakness
    • Muscle or joint pain
  • Your doctor may check your liver function before starting treatment and regularly thereafter.
  • Notify your doctor if you notice signs of liver problems, such as:
    • Stomach pain
    • Unusually dark urine
    • Yellowing of the skin or eyes
  • Lifestyle changes may enhance the effectiveness of this medication, including:
    • Following a low-fat and low-salt diet
    • Engaging in regular exercise
    • Avoiding smoking
    • Reducing alcohol consumption
  • Take the medication as per the dose and duration recommended by your doctor.
  • It can be taken with or without food.
  • Your doctor may conduct regular blood tests to monitor:
    • Lipid levels
    • Kidney function
    • Lung function
  • Inform your doctor if you experience muscle pain or weakness while taking this medication.
  • Notify your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
  • Do not discontinue Bempedoic acid abruptly without consulting your doctor.

Other Combinations

Bempedoic acid + Ezetimibe

Bempedoic acid + Rosuvastatin

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Frequently asked questions

HDL, or high-density lipoprotein, is known as 'good cholesterol' because it transports cholesterol from the blood to the liver for removal, thereby reducing heart disease risk.
LDL, or low-density lipoprotein, is termed 'bad cholesterol' because it contributes to cholesterol buildup in the blood, leading to blockages and increasing the risk of heart attacks, strokes, and peripheral artery disease.
Tiredness and fatigue are potential side effects of Bempedoic acid. If you experience fatigue along with chest pain or rapid heartbeat, contact your doctor immediately as these may indicate an emergency.
You can schedule a lipid profile test at an accredited laboratory to check your total cholesterol, LDL, HDL, triglycerides, and cholesterol-to-HDL ratio. Fasting for 10-12 hours before the test may be required. Consult your doctor to interpret the results.
Bempedoic acid may affect liver function but rarely causes liver damage. It can increase liver enzyme levels, which typically resolve with continued use or after stopping the medication.
High cholesterol can accumulate in artery walls, narrowing them and reducing blood flow to the heart, which may lead to heart attacks or strokes.
Take one tablet of Bempedoic acid once daily, with or without food, as prescribed by your doctor. Always adhere to your doctor's instructions.
Normal cholesterol levels are: total cholesterol 125-200 mg/dL, LDL less than 100 mg/dL, and HDL 40 mg/dL or higher.
Bempedoic acid can reduce cholesterol levels by 17-28% after 12 weeks of treatment.
A doctor will avoid prescribing Bempedoic acid if you have a history of tendon rupture, as this is a possible side effect. Risk factors include being over 60 years old or having kidney failure.
To improve the effectiveness of Bempedoic acid, adopt a low-fat diet, exercise regularly, maintain a healthy weight, and limit alcohol consumption.
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