Safepraz Plus Capsule SR is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort. Safepraz Plus Capsule SR is taken without food, following the dosage and duration recommended by your doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are stomach pain, diarrhea, headache, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results. Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Written by: Syed Jommy Abbas, B. Pharma
Reviewed by: Dr. Devika Rani, MBBS
Last updated on: 30-04-2025
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Safepraz Plus Capsule SR is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort. Safepraz Plus Capsule SR is taken without food, following the dosage and duration recommended by your doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you discontinue treatment prematurely, there is a risk of symptom recurrence and worsening of your condition. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine. The most common side effects are stomach pain, diarrhea, headache, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results. Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.
Treatment of Gastroesophageal reflux disease (Acid reflux) / Peptic ulcer disease
In Treatment of Gastroesophageal reflux disease (Acid reflux) Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Safepraz Plus Capsule SR reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed. In Peptic ulcer disease Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Safepraz Plus Capsule SR reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Diarrhea, Stomach pain, Flatulence, Dizziness']
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Safepraz Plus Capsule SR is to be taken empty stomach.
Safepraz Plus Capsule SR is a combination of two medicines: Cinitapride and Pantoprazole, which relieves symptoms of gastroesophageal reflux disease (GERD). Cinitapride is a prokinetic which facilitates the movement of intestines, thereby increasing the frequency of bowel movements, softening stools, and reducing abdominal pain/discomfort. Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Alcohol
Caution: It is important to consult your doctor regarding alcohol consumption while taking Safepraz Plus Capsule SR .
Pregnancy
Seek medical advice from your doctor: Information regarding the use of Safepraz Plus Capsule SR during pregnancy is not available. Doctor consultation is advised.
Breast feeding
Seek medical advice from your doctor: Information regarding the use of Safepraz Plus Capsule SR during breastfeeding is not available. Doctor consultation is advised.
Driving
Not Safe: Safepraz Plus Capsule SR may cause side effects which could affect your ability to drive.
Kidney
Seek medical advice from your doctor: There is limited information available on the use of Safepraz Plus Capsule SR in patients with kidney disease. Doctor consultation is advised.
Liver
Safe when prescribed by an expert: Safepraz Plus Capsule SR is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Safepraz Plus Capsule SR may not be needed in these patients. Doctor consultation is advised.
If a dose of Safepraz Plus Capsule SR is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Store in a cool and dry place, and keep the temperature below 30�C
It is a well-tolerated medicine and provides relief for a long time. Take it one hour before the meal, preferably in the morning. Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away. Do not consume alcohol while taking Safepraz Plus Capsule SR as it can increase the risk of stomach damage. Long-term use may cause weak or broken bones. Take adequate intake of dietary calcium and vitamin D or their supplements. Do not take it for longer than prescribed.
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