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Pregabalin 75mg + Vitamin B12 (Methylcobalamin) 500mcg

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Preplus M 500mcg/75mg Tablet

Preplus M 500mcg/75mg Tablet

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Long Expiry

Long Expiry
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Used In

Treatment of Neuropathic pain

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More About Preplus M 500mcg/75mg Tablet

Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Treatment of Neuropathic painTreatment of Neuropathic pain

In Treatment of Neuropathic pain Preplus M 500mcg/75mg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction. Taking Preplus M 500mcg/75mg Tablet regularly will improve your physical and social functioning and overall quality of life.In Treatment of Neuropathic pain Preplus M 500mcg/75mg Tablet is a combination of medicines used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. Pregabalin, an active ingredient of this medicine, is thought to work by interfering with pain signals that travel through the damaged nerves and the brain. It also contains nutritional supplements that improve nerve conduction. Taking Preplus M 500mcg/75mg Tablet regularly will improve your physical and social functioning and overall quality of life.

Side Effects

The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.

How to use

Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Preplus M 500mcg/75mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Preplus M 500mcg/75mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.

How it works

Preplus M 500mcg/75mg Tablet is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).Preplus M 500mcg/75mg Tablet is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).

Alcohol

Unsafe: Avoid consuming alcohol with Preplus M 500mcg/75mg Tablet as it is deemed unsafe.Unsafe: Avoid consuming alcohol with Preplus M 500mcg/75mg Tablet as it is deemed unsafe.

Pregnancy

Seek medical advice from your doctor: Preplus M 500mcg/75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.Seek medical advice from your doctor: Preplus M 500mcg/75mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.

Breast feeding

Seek medical advice from your doctor: Preplus M 500mcg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Seek medical advice from your doctor: Preplus M 500mcg/75mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Not Safe: Preplus M 500mcg/75mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.Not Safe: Preplus M 500mcg/75mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Caution Advised: Preplus M 500mcg/75mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Preplus M 500mcg/75mg Tablet may be needed. Doctor consultation is advised.Caution Advised: Preplus M 500mcg/75mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Preplus M 500mcg/75mg Tablet may be needed. Doctor consultation is advised.

Liver

Safe when prescribed by an expert: Preplus M 500mcg/75mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Preplus M 500mcg/75mg Tablet may not be needed in these patients. Doctor consultation is advised.Safe when prescribed by an expert: Preplus M 500mcg/75mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Preplus M 500mcg/75mg Tablet may not be needed in these patients. Doctor consultation is advised.

What if I forget to take it?

If a dose of Preplus M 500mcg/75mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.If a dose of Preplus M 500mcg/75mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Manufacturer Address

Regus Business Centre, 2nd Floor, Altius, Olympia Tech Park - 600 032, SIDCO Industrial Estate, Guindy, Chennai, India

Frequently asked questions

Regular check-ups may be necessary after starting Preplus M 500mcg/75mg Tablet. Consult your doctor if symptoms do not improve or if side effects disrupt your daily activities.
Preplus M 500mcg/75mg Tablet is a combination of Pregabalin and Methylcobalamin used to treat nerve pain by calming damaged nerves and aiding nerve regeneration.
If you miss a dose and it's close to the next one, skip the missed dose. If you remember earlier, take it and return to your normal schedule. Do not double the dose.
Initial benefits may be seen after 2 weeks, but full effects can take 2-3 months or longer for some patients.
No, avoid alcohol as it can worsen drowsiness caused by Preplus M 500mcg/75mg Tablet.
No, continue taking Preplus M 500mcg/75mg Tablet as prescribed by your doctor to avoid withdrawal symptoms. Gradual tapering may be necessary before stopping.
Yes, Preplus M 500mcg/75mg Tablet can cause drowsiness or sudden sleep episodes. Avoid risky activities until you know how it affects you, and inform your doctor if this occurs.
Preplus M 500mcg/75mg Tablet may increase hunger, leading to weight gain. To prevent this, maintain a balanced diet, avoid high-calorie foods, and exercise regularly.
Store Preplus M 500mcg/75mg Tablet in a cool, dry place, out of reach of children. Dispose of unused medications safely to prevent accidental consumption.
No, taking a higher dose can increase the risk of serious side effects. Consult your doctor if symptoms worsen despite the recommended dose.
Serious side effects are rare but can include allergic reactions, suicidal thoughts, or limb swelling. Contact your doctor if you notice any concerning symptoms.

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References

  • Pregabalin (22 Apr. 2019)

  • Pregabalin (22 Apr. 2019)

  • Methylcobalamin and pregabalin (14 Apr. 2025)

  • Methylcobalamin and pregabalin (14 Apr. 2025)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.