Metolactone 5 mg/50 mg Tablet
Metolactone 5 mg/50 mg Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It reduces the excess fluid levels in your body while maintaining potassium balance. It is best to take Metolactone 5 mg/50 mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Diarrhea, stomach upset, and glucose intolerance are very common side effect of this medicine. It might lower down the electrolytes level like sodium, potassium, and magnesium in the blood. Hence, regular monitoring of kidney function, blood pressure, and electrolytes are important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving. Before taking this medicine, tell your doctor if you have any liver or kidney disease. Inform your doctor if you are pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Written by: Srishti Bhukta, B. Pharma
Reviewed by: Dr. Varinderjeet Kaur, MBBS
Last updated on: 31-05-2025
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More About Metolactone 5 mg/50 mg Tablet
Quick Summary
Metolactone 5 mg/50 mg Tablet is a combination of two medicines used to treat hypertension (high blood pressure). It reduces the excess fluid levels in your body while maintaining potassium balance. It is best to take Metolactone 5 mg/50 mg Tablet in the morning along with food in order to avoid frequent urination at night time. For better results, it is suggested to take it at the same time every day. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you. Diarrhea, stomach upset, and glucose intolerance are very common side effect of this medicine. It might lower down the electrolytes level like sodium, potassium, and magnesium in the blood. Hence, regular monitoring of kidney function, blood pressure, and electrolytes are important while using this medicine. It might cause dizziness or tiredness if happens rise slowly from sitting position or avoid driving. Before taking this medicine, tell your doctor if you have any liver or kidney disease. Inform your doctor if you are pregnant. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.
Benefits of Metolactone 5 mg/50 mg Tablet
Hypertension (high blood pressure)
In Hypertension (high blood pressure) Metolactone 5 mg/50 mg Tablet relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This maintains balance of electrolytes (like potassium), lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.
Side Effects of Metolactone 5 mg/50 mg Tablet
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Upset stomach, Glucose intolerance, Breast enlargement in male, Irregular menstrual cycle, Increased blood lipid level, Increased uric acid level in blood, Electrolyte imbalance, Impotence']
Directions for Use
Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Metolactone 5 mg/50 mg Tablet is to be taken with food.
How it works
Metolactone 5 mg/50 mg Tablet is a combination of two diuretics: Metolazone and Spironolactone. They work by removing extra water and certain electrolytes from the body through urine. Over time, metolazone also relaxes blood vessels but causes potassium loss. Spironolactone is added as it conserves potassium, thereby balancing its levels in the body.
Alcohol
Unsafe: Avoid consuming alcohol with Metolactone 5 mg/50 mg Tablet as it is deemed unsafe.
Pregnancy
Seek medical advice from your doctor: Metolactone 5 mg/50 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Safe when prescribed by an expert: Metolactone 5 mg/50 mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
Not Safe: Metolactone 5 mg/50 mg Tablet may cause side effects which could affect your ability to drive. As Metolactone 5 mg/50 mg Tablet may cause drowsiness, dizziness, blurred vision, or lightheadedness and this may affect your ability to drive.
Kidney
Caution Advised: Metolactone 5 mg/50 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Metolactone 5 mg/50 mg Tablet may be needed. Doctor consultation is advised. Use of Metolactone 5 mg/50 mg Tablet is not recommended in patients with severe kidney disease.
Liver
Seek medical advice from your doctor: There is limited information available on the use of Metolactone 5 mg/50 mg Tablet in patients with liver disease. Doctor consultation is advised.
What If You Forget to take Metolactone 5 mg/50 mg Tablet?
If a dose of Metolactone 5 mg/50 mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.
Storage Advice
Store in a cool and dry place, and keep the temperature below 30�C
Quick Tips for Metolactone 5 mg/50 mg Tablet
You have been prescribed Metolactone 5 mg/50 mg Tablet for the treatment of high blood pressure. Monitor your blood pressure after starting Metolactone 5 mg/50 mg Tablet and notify your doctor if it does not lower down. Your doctor may get regular tests done to monitor the level of urea and lipid in your blood. Metolactone 5 mg/50 mg Tablet helps you to lose water via urination. If, however, you lose too much fluid, you may become dehydrated. This will make you feel thirsty and make your skin look and feel dry. Let your doctor know if this happens, as your dose may need to be adjusted. Avoid taking anti-inflammatory medicines such as Ibuprofen along with this medicine without consulting your doctor. Lifestyle changes like a low-sodium diet, exercise, and not smoking may help this medicine work better.
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