Maball 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis. Maball 500mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B. Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Written by: Syeda Jigni Mehraj, B pharmacy
Reviewed by: Dr. Jay Faldu, MBBS
Last updated on: 31-05-2025
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Maball 500mg Injection is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis. Maball 500mg Injection is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B. Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Non-Hodgkin lymphoma (NHL) / Rheumatoid arthritis / Blood cancer (Chronic lymphocytic leukemia) / Granulomatosis with polyangiitis / Microscopic polyangiitis
In Non-Hodgkin lymphoma (NHL) Non-Hodgkin's lymphoma is a cancer of the white blood cells in our body, also called mantle-cell lymphoma. White blood cells are those cells that help us to fight infections. Maball 500mg Injection lowers immune response and helps to reduce pain and inflammation. It also kills the cancer cells and helps prevent their further growth. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to. In Rheumatoid arthritis Maball 500mg Injection helps treat inflammation, pain and swelling in rheumatoid arthritis by decreasing the immune system response of the patient. It is given in the dose and frequency that suits your condition. This will be decided by the doctor. You must follow your doctor?s instructions carefully and let your doctor know if you have fever, chills or any bothersome side effects after taking this medicine. In Blood cancer (Chronic lymphocytic leukemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Maball 500mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but you should discuss the side effects and benefits of this medicine with your doctor. Let your doctor know if any of the side effects bothers you. In Granulomatosis with polyangiitis Granulomatosis with polyangiitis is a condition that causes inflammation of the blood vessels of the ears, nose, throat, lungs, and kidneys. In this condition, the blood flow to these areas may be reduced and it can lead to their damage. Maball 500mg Injection helps reduce inflammation, pain and swelling and prevents further damage. This improves your quality of life. In Microscopic polyangiitis Microscopic polyangiitis is an autoimmune disease which occurs in the small blood vessels and may be caused due to problems with the immune system. Maball 500mg Injection reduces immune response and improves inflammation. This helps to heal this condition and improves your discomfort.
The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them. ['Weakness, Infection, Chills, Decreased white blood cell count (neutrophils), Fever, Infusion site reaction, Lymphopenia, Abdominal pain, Back pain']
Your doctor or nurse will give you this medicine. Kindly do not self administer.
Maball 500mg Injection is a monoclonal antibody. It works by targeting the unwanted activity of immune cells (B cells) in rheumatoid arthritis and certain types of cancers.
Alcohol
Caution: It is important to consult your doctor regarding alcohol consumption while taking Maball 500mg Injection .
Pregnancy
Seek medical advice from your doctor: Maball 500mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.
Breast feeding
Safe when prescribed by an expert: Maball 500mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
Seek medical advice from your doctor: It is not known whether Maball 500mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
Safe when prescribed by an expert: Maball 500mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Maball 500mg Injection may not be needed in these patients. Doctor consultation is advised.
Liver
Seek medical advice from your doctor: There is limited information available on the use of Maball 500mg Injection in patients with liver disease. Doctor consultation is advised. Use of Maball 500mg Injection is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.
If a dose of Maball 500mg Injection is missed, it's advisable to consult your doctor.
Store in a refrigerator (2 - 8�C). Do not freeze.
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