Acetril PS 100/325/15mg Tablet 10s

Acetril Ps 100 325 15mg Tablet 10s is a powerful, triple-action tablet designed to relieve pain, reduce swelling, and treat inflammation. It combines Aceclofenac (a potent anti-inflammatory painkiller), Paracetamol (a common pain reliever and fever reducer), and Serratiopeptidase (an enzyme that helps reduce swelling and speeds up healing). This combination is widely used to treat painful conditions such as muscle aches, joint pain, backache, and post-operative pain, providing effective, fast-acting relief by targeting both pain and underlying inflammation.

This medication is an advanced prescription treatment engineered for the comprehensive management of acute pain and inflammation arising from various injuries and joint conditions. Acetril Ps 100 325 15mg Tablet 10s works by initiating a three-pronged attack on discomfort, swelling, and the biological processes that cause them.

The primary anti-inflammatory agent is Aceclofenac, a Non-Steroidal Anti-Inflammatory Drug (NSAID). When your body is injured, it releases chemical messengers called prostaglandins, which trigger pain, swelling, and redness. Aceclofenac works by firmly blocking the production of these specific messengers at the injury site, directly reducing the core symptoms of inflammation.

Complementing this effect is Paracetamol (Acetaminophen). This component focuses on providing fast, centralised relief. It primarily acts in the brain and spinal cord to increase the body’s tolerance to pain, making the discomfort feel significantly less intense. It also works on the brain’s temperature control centre to quickly reduce any associated fever. This dual-action provides rapid, generalised relief without increasing the stomach irritation risks associated with NSAIDs.

Finally, Serratiopeptidase is a unique enzyme that acts like a clean-up crew. It helps break down abnormal proteins, such as fibrin, at the site of inflammation or injury. By dissolving this unwanted material and thinning the fluid build-up (oedema), the enzyme dramatically reduces swelling, improves blood circulation, and allows the other two painkillers to reach the affected area more effectively, promoting faster recovery. This integrated action makes Acetril Ps 100 325 15mg Tablet 10s one of the most effective solutions for conditions where pain and swelling coexist.

Acetril Ps 100 325 15mg Tablet 10s is prescribed for the short-term relief and management of various inflammatory, painful, and febrile conditions, focusing on musculoskeletal and soft-tissue injury recovery:

• Relief from acute muscle pain, including severe backache, stiffness, lumbago, and muscle strains.
• Management of pain, swelling, and reduced joint mobility in active phases of osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.
• Reduction of pain and swelling following accidental injury, sprains, fractures, or dislocations (post-traumatic pain).
• Alleviation of pain and tenderness after various surgical and dental procedures (post-operative pain).
• Treatment of painful inflammation in soft tissues like tendons (tendonitis) and fluid sacs (bursitis).

The combination of Aceclofenac, Paracetamol, and Serratiopeptidase offers several key therapeutic advantages over single-ingredient painkillers:

• Comprehensive Pain and Swelling Control: The medicine provides a three-in-one mechanism: reducing core inflammation (Aceclofenac), blocking pain signals (Paracetamol), and physically clearing debris/reducing fluid build-up (Serratiopeptidase).
• Enhanced Tissue Healing: Serratiopeptidase acts as a catalyst, dissolving dead or damaged tissues and reducing swelling faster than the body can on its own. This speeds up the overall recovery process.
• Rapid Symptom Alleviation: Paracetamol provides immediate relief, while the other two components work to treat the underlying inflammation and swelling over a sustained period.
• Improved Mobility: By powerfully reducing both pain and inflammation, the medicine helps restore range of motion in affected joints and muscles, accelerating the patient's return to normal function.
• Lower Overall Risk: The inclusion of Paracetamol and the enzyme allows doctors to manage pain effectively without relying solely on a maximum dose of the NSAID (Aceclofenac), potentially mitigating some gastrointestinal risks.

Due to the potent nature of its three components, Acetril Ps 100 325 15mg Tablet 10s can cause a range of side effects. Patients must monitor their body’s response closely and report any concerning symptoms to their doctor.

Common Side Effects (Mild and Usually Temporary)

• Gastrointestinal Distress: Nausea, vomiting, abdominal pain, stomach upset, or indigestion.

• Diarrhoea: This is a frequently reported side effect.

• General Discomfort: Headache, dizziness, or mild fatigue.

• Skin Reactions: Mild rash or itching.

Serious and Rare Side Effects (Requires Immediate Medical Attention)

• Severe Gastrointestinal Bleeding: Look out for black, tarry stools (like dried blood) or vomiting material that resembles coffee grounds. This is a life-threatening risk associated with Aceclofenac and requires emergency care.

• Hepatotoxicity (Liver Damage): Due to the Paracetamol component, especially at high doses. Symptoms include yellowing of the skin or eyes (jaundice), dark urine, pale stools, and unexplained, persistent tiredness.

• Nephrotoxicity (Kidney Problems): NSAIDs can harm the kidneys, particularly with long-term use or in dehydrated patients. Signs include a noticeable change in the amount or frequency of urination, or persistent swelling in the hands or feet.

• Severe Allergic Reactions: Sudden, severe rash, swelling of the face, lips, or throat, or difficulty breathing.

Disclaimer: If you notice any signs of bleeding, liver issues, or severe allergy, stop the medication immediately and contact emergency medical services.

Proper use of Acetril Ps 100 325 15mg Tablet 10s is vital for safety and achieving effective relief:

• Follow Directions: Take the tablet exactly as prescribed by your doctor regarding the dose, frequency, and duration of the course.
• Swallow Whole: Swallow the tablet whole with a full glass of water. Do not crush, chew, or split the tablet, as this can severely increase the risk of stomach irritation.
• Take With Food: It is strongly recommended to take this medication with food or immediately after a meal. This helps to protect your stomach lining from the irritating effects of Aceclofenac.
• Short-Term Use: This medicine is typically for short-term pain control (usually 5 to 7 days). Do not continue taking it beyond the prescribed duration without consulting your doctor.
• Consistent Timing: For consistent pain control, try to take the doses at the same time each day.

• Store Acetril Ps 100 325 15mg Tablet 10s in the original packaging at room temperature, below 30 degrees Celsius.
• The medicine should be kept in a cool, dry place, away from moisture and direct sunlight.
• Keep the medicine out of the sight and reach of children and pets.
• Do not use the medicine if the expiry date printed on the pack has passed.

The primary interactions relate to safety and habit-forming lifestyle choices:

• Alcohol: As stated in the safety section, alcohol is a significant interaction that severely escalates the risks of liver toxicity (Paracetamol) and gastrointestinal bleeding (Aceclofenac). Avoid completely.
• Smoking: Tobacco smoke may increase the metabolism of specific components in the liver. More importantly, smoking is a known risk factor for gastrointestinal ulcers, significantly increasing the risk of bleeding when combined with Aceclofenac.
• Spicy/Acidic Foods: While not a direct drug interaction, consuming highly spicy or acidic foods may increase the risk of mild stomach discomfort or irritation, which is already a potential side effect of Aceclofenac.

Always inform your doctor about all current prescriptions, over-the-counter medications, and supplements:

• Blood Thinners (e.g., Warfarin): The risk of severe bleeding is significantly increased when combined with Aceclofenac and Paracetamol.
• Other NSAIDs (e.g., Ibuprofen, Naproxen): Taking other NSAIDs should be avoided as they increase the risk of stomach irritation and side effects without additional benefit.
• Medicines containing Paracetamol: Must be avoided to prevent accidental overdose and liver toxicity.
• Diuretics (Water Tablets): Aceclofenac can reduce the effect of diuretics and increase the risk of kidney problems.

Patients with certain conditions must use Acetril Ps 100 325 15mg Tablet 10s with caution:

• Liver Disease: Risk of liver damage is high, mainly due to Paracetamol. Use is not recommended in severe liver impairment.
• Kidney Impairment: Aceclofenac (NSAID) can negatively affect kidney function. Close monitoring or dose adjustment is required.
• Gastrointestinal Ulcers/Bleeding: Aceclofenac increases the risk of stomach ulcers and bleeding. Patients with a history of these issues should use it with extreme caution.
• Heart Disease: NSAIDs like Aceclofenac may increase the risk of heart attack or stroke, particularly with long-term use.

The usual recommended dose is one tablet two to three times daily after meals, or as directed by your doctor. Do not exceed the prescribed dose. Your doctor may adjust the dose based on your pain severity, inflammation, and overall health condition. Continue taking the medicine for the prescribed duration even if symptoms improve, unless advised otherwise.

Taking more than the recommended dose may increase the risk of side effects such as stomach pain, nausea, vomiting, dizziness, gastrointestinal bleeding, or liver toxicity. Seek immediate medical attention if an overdose is suspected. Supportive treatment may include stomach protection, fluid replacement, and monitoring of liver and kidney function under medical supervision.

If you miss a dose of Acetril Ps 100 325 15mg Tablet 10s, take it as soon as you remember. However, if it is already time for your next scheduled dose, skip the missed dose entirely and continue with your regular dosing schedule. Do not double the dose to compensate for the forgotten one, as taking too much Aceclofenac or Paracetamol dramatically increases the risk of severe side effects, especially liver damage.