Sulbactam

Uses

Sulbactam is used in the treatment of severe bacterial infections. It is effective against severe bacterial infections, most commonly pneumonia, bacteremia, and skin and skin structure infections, caused by the pathogen Acinetobacter baumannii.

How it Works

How Sulbactam works Sulbactam is a beta-lactamase inhibitor that functions by blocking an enzyme called beta-lactamase, which is produced by bacteria to inactivate antibiotics. Sulbactam is often combined with beta-lactam antibiotics, such as ampicillin, cefoperazone, and meropenem. As a standalone medication, it treats infections caused by the bacterium Acinetobacter baumannii. This activity is mediated by its interaction with specific proteins.

Side Effects

Common side effects of sulbactam include diarrhea and pain at the injection site.

Expert Advice

Sulbactam is used in the treatment of severe bacterial infections, in combination with certain antibiotics.
It is also used alone for serious infections caused by the pathogen Acinetobacter baumannii, including those resistant to other antibiotics.
Sulbactam is preferentially administered as an injection directly into a vein over a period of 15-60 minutes.
When used alone, it is associated with few adverse effects, primarily pain at the injection site and diarrhea.

Other Combinations

Meropenem + Sulbactam

Cefuroxime + Sulbactam

Ceftriaxone + Disodium edetate + Sulbactam

Ceftriaxone + Sulbactam

Ceftazidime + Sulbactam

Cefoperazone + Sulbactam

Linezolid + Sulbactam

Cefepime + Sulbactam

Cefpodoxime Proxetil + Sulbactam

Ampicillin + Sulbactam

Cefotaxime + Sulbactam

Cefpirome + Sulbactam

Amoxycillin + Sulbactam

Cefixime + Sulbactam

Frequently asked questions

Does Sulbactam treat the flu?

No, Sulbactam does not treat viral infections such as the flu or the common cold.

Who should not take Sulbactam?

Individuals with a history of allergic reactions to ampicillin, sulbactam, or any penicillin antibiotics, as well as those with a history of liver problems related to these medications, should not take Sulbactam.

Why is Sulbactam added to other antibiotics?

Sulbactam is added to antibiotics like ampicillin and cefoperazone because it is a beta-lactamase inhibitor that reduces bacterial resistance and enhances the effectiveness of these antibiotics.

Can I use a discolored solution of Sulbactam?

No, do not use Sulbactam if the solution is discolored or contains particles, as this may indicate contamination and reduce its effectiveness. Discard the solution and use a new vial.

I feel better now. Can I stop taking Sulbactam?

No, continue taking Sulbactam as prescribed, even if you feel better. Stopping early can lead to incomplete treatment and increase the risk of developing antibiotic-resistant infections. Follow your doctor's advice for completing the course.

What should I discuss with my doctor before receiving Sulbactam?

Before taking Sulbactam, inform your doctor about any past allergic reactions to it or similar medications, as well as any allergies, asthma, heart disease, kidney disease, and all other medications you are currently taking. Pregnant or breastfeeding individuals should also consult their doctor.

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