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Primaquine

Uses

Primaquine is used in the treatment of malaria.

How it Works

How Primaquine works Primaquine is an antiparasitic medication used to treat malaria. It functions by increasing the levels of heme in the blood, a substance that is toxic to the malarial parasite. This action kills the parasite and prevents the infection from spreading.

Side Effects

Common side effects of Primaquine include rash, vomiting, dizziness, nausea, itching, epigastric pain, abdominal cramps, decreased white blood cell count (lymphocytes), hemolytic anemia, arrhythmia (irregular heartbeats), and QT interval prolongation.

Expert Advice

  • Primaquine is used for the prevention and treatment of malaria.
  • Take it with food to decrease the risk of stomach upset.
  • Tips to reduce the chance of being bitten by mosquitoes:
    • Wear light-colored and covered clothing when you are outside after sunset.
    • Use insect repellent creams or sprays on parts of your body not covered by clothing.
    • Spray to kill any mosquitoes that may have entered rooms despite screening.
  • It may cause blurring of vision when you first start taking it. Use caution while driving or performing tasks that require concentration.
  • An eye examination before and at 3–6 month intervals during use is required if patients are receiving Primaquine at continuous high doses for an extended duration.
  • It may cause low blood sugar levels. Monitor your blood sugar level regularly if you are diabetic.
  • When used long-term, your doctor may monitor the amounts of different types of blood cells in your blood regularly.
  • Inform your doctor if you experience unexplained bruising or bleeding, sore throat, fever, or a general feeling of tiredness.

Other Combinations

Chloroquine + Primaquine

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Frequently asked questions

Primaquine is safe when taken as prescribed by your doctor. Follow the dosage instructions carefully and report any bothersome side effects.
Patients allergic to Primaquine or its components should avoid its use. If you are unsure about an allergy or using Primaquine for the first time, consult your doctor.
No, do not stop taking Primaquine without consulting your doctor, even if you feel better. Your symptoms may improve before the infection is fully treated, so continue the medication for the prescribed duration.
If you forget a dose, take it as soon as you remember. If it's nearly time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to compensate for the missed one.
Before starting Primaquine, inform your doctor about any health issues, especially related to the kidneys or heart, as these may require dose adjustments. Also, disclose all other medications you are taking and if you are pregnant or breastfeeding.
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