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Fenofibrate

Uses

Fenofibrate is used in the treatment of high cholesterol and high triglycerides.

How it Works

How Fenofibrate works Fenofibrate is a lipid-lowering medication. It functions by decreasing the levels of triglycerides and "bad" cholesterol (LDL), while increasing the levels of "good" cholesterol (HDL).

Side Effects

Common side effects of Fenofibrate include abdominal pain, diarrhea, nausea, headache, flatulence, vomiting, increased liver enzymes, elevated creatine phosphokinase (CPK) levels in the blood, back pain, and inflammation of the nose.

Expert Advice

  • Fenofibrate should be taken with food.
  • Avoid alcohol consumption while taking this medication.
  • Your doctor may check your liver function before starting treatment and regularly thereafter.
  • Notify your doctor if you experience:
    • Increased fatigue
    • Loss of appetite
    • Yellowing of the eyes or skin
    • Dark urine
  • Inform your doctor if you experience muscle pain, tenderness, cramps, or weakness while taking Fenofibrate, especially if accompanied by a fever.
  • Do not discontinue Fenofibrate without consulting your doctor, even if you feel better.
  • Fenofibrate is the medication of choice for lowering triglyceride levels in the blood.
  • It can reduce triglycerides by up to 50%.
  • Fenofibrate decreases the risk of heart disease and helps prevent stroke and heart attack.
  • Take Fenofibrate along with regular exercise and a low-fat diet to lower fat levels in the blood.

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Frequently asked questions

When should Fenofibrate be taken?
Fenofibrate is typically taken once daily with a meal. The initial dose varies based on the patient's type and age. Consult your doctor before starting the medication and follow their instructions.
Can Fenofibrate cause kidney problems?
Fenofibrate should be used cautiously in patients with kidney disorders. Long-term use may increase serum creatinine levels, but this is usually reversible. Regular kidney function tests are recommended if kidney damage is a concern. Consult your doctor regarding any pre-existing conditions and medications.
Does Fenofibrate raise blood pressure?
Fenofibrate generally has no significant effect on blood pressure in individuals with normal levels. It may, however, lower blood pressure in patients with hypertension.
Can I take grapefruit juice with Fenofibrate?
Yes, Fenofibrate can be taken with grapefruit juice, as they are metabolized by different enzymes in the body. If uncertain, consider limiting grapefruit juice intake while on Fenofibrate.
What drugs should not be taken with Fenofibrate?
Certain medications, such as oral anticoagulants, ciclosporin, statins, and contraceptives, should not be taken with Fenofibrate. Provide your doctor with a complete medication history to ensure safe and effective treatment.
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