Epalrestat + Pregabalin + Vitamin B12 (Methylcobalamin)

Uses

Epalrestat, Methylcobalamin, and Pregabalin are used in the treatment of diabetic nerve pain.

How it Works

How Epalrestat, Methylcobalamin, and Pregabalin work Epalrestat, Methylcobalamin, and Pregabalin is a combination of three medicines used to treat diabetic nerve disease. Epalrestat is an aldose reductase inhibitor that blocks the accumulation of sorbitol in cells, which contributes to diabetic nerve disease. Methylcobalamin is a form of vitamin B that aids in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha-2-delta ligand that decreases pain by modulating the calcium channel activity of nerve cells.

Side Effects

Common side effects of Epalrestat, Methylcobalamin, and Pregabalin include nausea, vomiting, drowsiness, dizziness, tiredness, uncoordinated body movements, and increased liver enzymes.

Expert Advice

Take the medication only as per the dose and duration prescribed by your doctor.
Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
Inform your doctor if you have:

Cut or sore on your feet that is infectious or not healing
Burning or tingling sensation in arms or feet that hampers your routine activities
Trouble with digestion, urination, or sexual functioning
Dizziness