Epalrestat + Vitamin B12 (Methylcobalamin)

Uses

Epalrestat and Methylcobalamin are used in the treatment of diabetic nerve pain.

How it Works

How Epalrestat and Methylcobalamin Work Epalrestat and methylcobalamin is a combination of two medicines used to treat diabetic nerve disease. Epalrestat is an aldose reductase inhibitor that blocks the accumulation of sorbitol in cells, which is associated with the development of diabetic nerve disease. Methylcobalamin is a form of vitamin B that aids in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells.

Side Effects

Common side effects of Epalrestat and Methylcobalamin include nausea, vomiting, and increased liver enzymes.

Expert Advice

  • Take the medication only as per the dose and duration prescribed by your doctor.
  • Adherence to antidiabetic therapy can delay the onset of or prevent diabetic nerve disease.
  • Inform your doctor if you have:
    • Cut or sore on your feet that is infectious or not healing
    • Burning or tingling sensation in arms or feet that hampers your routine activities
    • Trouble with digestion, urination, or sexual functioning
    • Dizziness
  • To prevent diabetic nerve pain:
    • Wear proper footwear
    • Examine your feet every day to detect lesions early
  • Monitor your blood sugar level regularly.
  • Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

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