Cyclophosphamide

Uses

Cyclophosphamide is used in the treatment of cancer and nephrotic syndrome.

How it Works

How Cyclophosphamide works Cyclophosphamide is an anti-cancer medication. It is an alkylating agent that functions by damaging the genetic material (DNA and RNA) of cancer cells, thereby inhibiting their growth and multiplication. This is how it acts against cancer.

Side Effects

Common side effects of Cyclophosphamide include hair loss, nausea, infection, diarrhea, vomiting, decreased white blood cell count (neutrophils), decreased white blood cell count (lymphocytes), myelosuppression, cystitis, and microhematuria.

Expert Advice

Cyclophosphamide is used in the treatment of cancer.
Drink plenty of fluids or urinate frequently to prevent urinary problems while taking this medication.
Take it with food if you experience stomach irritation, preferably in the morning.
Your doctor may perform regular blood tests to monitor your blood counts during treatment with this medication.
You are at an increased risk of getting sick or healing more slowly while on this medication.
Consult your doctor before receiving any vaccines.
Contact your doctor immediately if you experience difficulty urinating or notice blood in your urine while on this medication.
Do not take Cyclophosphamide if you are pregnant or breastfeeding.
Use an effective contraception method to prevent pregnancy while taking this medicine.

Other Combinations

Capecitabine + Cyclophosphamide

Frequently asked questions

Can Cyclophosphamide cause cancer?

Yes, Cyclophosphamide and other cancer treatments can increase the risk of developing secondary cancers, which may arise years after treatment. The risk is notably higher for bladder cancer, and rare cancers such as Acute leukemia, Myelodysplastic syndrome, and ureter cancer may also occur.

Can Cyclophosphamide cause infertility?

Yes, Cyclophosphamide can lead to infertility in both men and women by disrupting the menstrual cycle in women and inhibiting sperm production in men. If you plan to have children after treatment, consult your doctor about options like cryopreservation of sperm or eggs, as infertility may be irreversible.

Can Cyclophosphamide cause weight loss?

Yes, Cyclophosphamide may lead to weight loss due to reduced appetite, which could also be related to underlying cancer. If you are concerned about weight loss, consult your doctor.

Is Cyclophosphamide a chemotherapy medicine?

Yes, Cyclophosphamide is a chemotherapy drug classified as an alkylating agent, and it functions by killing cancer cells. It is also referred to as a cytotoxic medication.

Can Cyclophosphamide be used for non-cancer conditions?

Yes, Cyclophosphamide is used to treat nephrotic syndrome in children whose condition has not improved with other medications. Its safety and effectiveness for nephrotic syndrome in adults have not been established.

Do I need to avoid sun exposure during treatment with Cyclophosphamide?

No, there is no evidence suggesting the need to avoid sun exposure while taking Cyclophosphamide, although rare cases of skin and nail discoloration have been reported.

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