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Capecitabine + Cyclophosphamide

Uses

Capecitabine and Cyclophosphamide are used in the treatment of breast cancer.

How it Works

How Capecitabine and Cyclophosphamide Work Capecitabine and Cyclophosphamide is a combination of two anticancer medications. Capecitabine interferes with DNA production, halting cell growth and multiplication, which leads to the slowing or stopping of cancer progression. Cyclophosphamide damages the DNA of cancer cells, inhibiting their growth. Cancer cells divide more rapidly and with less error correction than normal cells, making them more susceptible to this damage.

Side Effects

Common side effects of Capecitabine and Cyclophosphamide include hand-foot syndrome, vomiting, and weakness.

Expert Advice

  • Do not receive any kind of immunization or vaccination without your doctor’s approval while taking Capecitabine + Cyclophosphamide.
  • Inform your doctor if you are pregnant or breastfeeding before taking this medicine.
  • You may be at risk of infection; hence, try to avoid crowds or individuals with colds.
  • Immediately report fever or any other signs of infection to your healthcare provider.
  • Hand-foot-mouth syndrome is one of the most common side effects of this medicine.
  • You may experience a skin rash, swelling, redness, pain, and/or peeling of the skin on the palms of your hands and soles of your feet.
  • To reduce nausea, take anti-nausea medications as prescribed by your doctor, and eat small, frequent meals.
  • Use contraceptives, and do not conceive a child (get pregnant) while taking Capecitabine + Cyclophosphamide.
  • Barrier methods of contraception, such as condoms, are recommended.
  • Avoid sun exposure by wearing SPF 15 (or higher) sunblock and protective clothing.

Other Combinations

Frequently asked questions

What should I do about skin changes after taking Capecitabine and Cyclophosphamide?
To manage rashes and dry skin, use a moisturizer, avoid direct sunlight, wear protective clothing, and apply sunscreen with SPF over 15 when outdoors. Refrain from swimming if you have a rash, as chlorine can aggravate it, and opt for cool showers and loose, cotton clothing. Skin conditions typically improve after treatment ends.
Should I avoid specific foods and drinks while on Capecitabine and Cyclophosphamide?
You can maintain your usual diet unless advised otherwise by your doctor. It's recommended to drink water regularly to stay hydrated, consume small, nutritious snacks frequently, and suck on hard candy or popsicles to help prevent nausea and vomiting.
What tests are required before starting treatment with Capecitabine and Cyclophosphamide?
You will need blood tests before and during treatment to monitor blood cell levels, as well as tests to evaluate liver and kidney function.
Are nausea and extreme tiredness common side effects of Capecitabine and Cyclophosphamide?
Yes, nausea and fatigue are common side effects. To alleviate nausea, eat smaller, more frequent meals and avoid salty, spicy, fried, or fatty foods. Ensure you rest adequately and engage in light exercise to combat fatigue.
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