Chlorpromazine and Trihexyphenidyl are used in the treatment of schizophrenia.
How Chlorpromazine and Trihexyphenidyl work Chlorpromazine and Trihexyphenidyl is a combination of two medicines: Chlorpromazine and Trihexyphenidyl. Chlorpromazine is a typical antipsychotic that works by blocking the action of a chemical messenger (dopamine) in the brain, which affects thoughts and mood. However, it may cause side effects such as involuntary movements, including shaking of the hands and muscle spasms. Trihexyphenidyl is added to treat and prevent these side effects.
Common side effects of Chlorpromazine and Trihexyphenidyl include nausea, constipation, sedation, weight gain, orthostatic hypotension (sudden lowering of blood pressure upon standing), urinary retention, increased prolactin levels in the blood, dizziness, blurred vision, dryness of the mouth, and nervousness.