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Chlorpromazine + Trihexyphenidyl

Uses

Chlorpromazine and Trihexyphenidyl are used in the treatment of schizophrenia.

How it Works

How Chlorpromazine and Trihexyphenidyl work Chlorpromazine and Trihexyphenidyl is a combination of two medicines: Chlorpromazine and Trihexyphenidyl. Chlorpromazine is a typical antipsychotic that works by blocking the action of a chemical messenger (dopamine) in the brain, which affects thoughts and mood. However, it may cause side effects such as involuntary movements, including shaking of the hands and muscle spasms. Trihexyphenidyl is added to treat and prevent these side effects.

Side Effects

Common side effects of Chlorpromazine and Trihexyphenidyl include nausea, constipation, sedation, weight gain, orthostatic hypotension (sudden lowering of blood pressure upon standing), urinary retention, increased prolactin levels in the blood, dizziness, blurred vision, dryness of the mouth, and nervousness.

Expert Advice

  • Chlorpromazine + Trihexyphenidyl is a combination medicine that helps treat schizophrenia.
  • Trihexyphenidyl controls drug-induced abnormal movements.
  • Be cautious while driving or engaging in activities that require concentration, as Chlorpromazine + Trihexyphenidyl can cause dizziness and sleepiness.
  • Avoid consuming alcohol while taking this medication, as it may lower its efficacy.
  • It can cause dry mouth; maintain good oral hygiene by:
    • Drinking water
    • Chewing sugarless gum
    • Sucking on hard candy
  • This medication can increase sensitivity to temperature changes; therefore:
    • Drink plenty of liquids
    • Dress appropriately for the weather
  • To reduce the risk of dizziness or fainting, rise slowly after sitting or lying down.
  • Inform your doctor if you have:
    • Glaucoma
    • Trouble passing urine
  • Do not stop taking Chlorpromazine + Trihexyphenidyl without consulting your doctor first, as it may worsen symptoms.

Other Combinations

Chlorpromazine + Trifluoperazine + Trihexyphenidyl

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