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100% Same

Salt CompositionEffectivenessStrength

50%

with Substitute Medicine

MoleculeSalt Composition in both

Metformin 500mg + Sitagliptin 100mg

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Siglyn M 100/500mg Tablet ER 10s
Siglyn M 100/500mg Tablet ER 10s
Siglyn M 100/500mg Tablet ER 10s

Siglyn M 100/500mg Tablet ER 10s

Zydus Healthcare Ltd.

Strip of 10 tablets

165

16.5 / Unit
Our Recommendation

Our Recommendation

Sitasmart M 100/500mg Tablet PR 10s

Sitasmart M 100/500mg Tablet PR 10s

Healing Pharma India Pvt. Ltd.
Strip of 10 tablets

1,368+ trust this

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Used In

Treatment of Type 2 diabetes mellitus

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More About Siglyn M

Siglyn M
Sitasmart
Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Treatment of Type 2 diabetes mellitusTreatment of Type 2 diabetes mellitus

In Treatment of Type 2 diabetes mellitus : Siglyn M 100/500 Tablet ER is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.In Treatment of Type 2 diabetes mellitus : Siglyn M 100/500 Tablet ER is a combination of two medicines that work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health.

Side Effects

Side effects of Siglyn M Tablet ERThe majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Siglyn MDecreased appetite Vomiting Upper respiratory tract infection Hypoglycemia (low blood glucose level)Abdominal bloating Nausea DiarrheaSide effects of Siglyn M Tablet ERThe majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you�re worried about them Common side effects of Siglyn MDecreased appetite Vomiting Upper respiratory tract infection Hypoglycemia (low blood glucose level)Abdominal bloating Nausea Diarrhea

How to use

How to use Siglyn M Tablet ERFollow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Siglyn M 100/500 Tablet ER is to be taken with food.How to use Siglyn M Tablet ERFollow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Siglyn M 100/500 Tablet ER is to be taken with food.

How it works

How Siglyn M Tablet ER works Siglyn M 100/500 Tablet ER is a combination of two medicines: sitagliptin and metformin. Sitagliptin help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.How Siglyn M Tablet ER works Siglyn M 100/500 Tablet ER is a combination of two medicines: sitagliptin and metformin. Sitagliptin help your pancreas produce more insulin, facilitate effective use of insulin by the body, and reduce excess sugar that your liver makes. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Together, they provide better control of blood sugar.

Alcohol

Unsafe: Avoid consuming alcohol with Siglyn M 100/500 Tablet ER as it is deemed unsafe.Unsafe: Avoid consuming alcohol with Siglyn M 100/500 Tablet ER as it is deemed unsafe.

Pregnancy

Siglyn M 100/500 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.Siglyn M 100/500 Tablet ER may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Doctor consultation is advised.

Breast feeding

Siglyn M 100/500 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Siglyn M 100/500 Tablet ER is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

Kidney

Siglyn M 100/500 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Siglyn M 100/500 Tablet ER may be needed. Doctor consultation is advised.Use of Siglyn M 100/500 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.Siglyn M 100/500 Tablet ER should be used with caution in patients with kidney disease. Dose adjustment of Siglyn M 100/500 Tablet ER may be needed. Doctor consultation is advised.Use of Siglyn M 100/500 Tablet ER is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.

Liver

Siglyn M 100/500 Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Doctor consultation is advised.Siglyn M 100/500 Tablet ER is probably unsafe to use in patients with liver disease and should be avoided. Doctor consultation is advised.

What if I forget to take it?

If a dose of Siglyn M 100/500 Tablet ER is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.If a dose of Siglyn M 100/500 Tablet ER is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Manufacturer Address

Zydus Tower, CTS No- 460/6 of Village Pahadi, Off I. B. Patel Road, Goregaon (East), Mumbai-400 063

Frequently asked questions

Are both Siglyn M & Sitasmart medicines exactly the same?
Yes, both medicines have the same salt composition, dosage, and effectiveness. They work the same way in your body. The only difference is the brand — and Sitasmart option is much more affordable without compromising on quality
What is Siglyn M 100/500mg Tab ER 10s?
Siglyn M 100/500mg Tab ER 10s is a combination of Sitagliptin and Metformin used to treat type 2 diabetes mellitus. It improves blood glucose levels in adults when combined with a proper diet and exercise. Metformin reduces liver glucose production and enhances insulin sensitivity, while Sitagliptin increases insulin release from the pancreas. It is not recommended for individuals under 18 years old.
What are the possible side effects of Siglyn M 100/500mg Tab ER 10s?
Common side effects of Siglyn M 100/500mg Tab ER 10s include hypoglycemia, altered taste, nausea, stomach pain, diarrhea, headache, and upper respiratory infections. Rare but serious side effects may include lactic acidosis and long-term use can lead to Vitamin B12 deficiency.
Can the use of Siglyn M 100/500mg Tab ER 10s lead to lactic acidosis?
Yes, Siglyn M 100/500mg Tab ER 10s can cause lactic acidosis, a rare but serious condition characterized by high lactic acid levels in the blood. Symptoms include muscle pain, dizziness, cold extremities, difficulty breathing, nausea, and slow heart rate. If these occur, stop taking Siglyn M 100/500mg Tab ER 10s and consult a doctor immediately.
Is it safe to take alcohol while I am taking Siglyn M 100/500mg Tab ER 10s?
No, consuming alcohol with Siglyn M 100/500mg Tab ER 10s is unsafe as it can increase the risk of lactic acidosis.
Can the use of Siglyn M 100/500mg Tab ER 10s lead to Vitamin B12 deficiency?
Yes, long-term use of Siglyn M 100/500mg Tab ER 10s can lead to Vitamin B12 deficiency by interfering with its absorption. Untreated deficiency may result in anemia and nerve issues, causing tingling, numbness, weakness, urinary problems, and balance difficulties. Annual Vitamin B12 supplementation is recommended to prevent these issues.
What are the instructions for storage and disposal of Siglyn M 100/500mg Tab ER 10s?
Store Siglyn M 100/500mg Tab ER 10s tightly closed in its original container according to the label instructions. Dispose of unused medicine properly to prevent accidental consumption by pets or children.
Are there any specific conditions in which Siglyn M 100/500mg Tab ER 10s should not be taken?
Siglyn M 100/500mg Tab ER 10s should be avoided in patients with allergies to its components, severe kidney or liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis.

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References

  • Sitagliptin/metformin hydrochloride. Haarlem, The Netherlands: Merck Sharp & Dohme BV; 2018 (08 Apr. 2019)

  • Sitagliptin/Metformin hydrochloride. London, UK: European Medicines Agency; 2013 (08 Apr. 2019)

  • Sitagliptin and metformin hydrochloride (08 Apr. 2019)

  • Sitagliptin and Metformin hydrochloride (20 Oct. 2021)

  • Sitagliptin and Metformin hydrochloride (20 Oct. 2021)

  • Sitagliptin and metformin hydrochloride (28th Sept. 2023)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.