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100% Same

Salt CompositionEffectivenessStrength

44%

with Substitute Medicine

MoleculeSalt Composition in both

Methotrexate 2.5mg

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Biotrexate 2.5mg Tablet

Biotrexate 2.5mg Tablet

Biochem Pharmaceutical Industries

Strip of 10 tablets

49.5

5 / Unit
Our Recommendation

Our Recommendation

Methoquest 2.5mg Tablet 10s

Methoquest 2.5mg Tablet 10s

Dr. Morepen Ltd.
Strip of 10 tablets

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Used In

Treatment of Rheumatoid arthritis / Treatment of Psoriasis

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More About Biotrexate

Biotrexate
Methoquest
Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Treatment of Rheumatoid arthritis / Treatment of PsoriasisTreatment of Rheumatoid arthritis / Treatment of Psoriasis

In Treatment of Rheumatoid arthritis Biotrexate 2.5mg Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective. In Treatment of Psoriasis Biotrexate 2.5mg Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Biotrexate 2.5mg Tablet works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.In Treatment of Rheumatoid arthritis Biotrexate 2.5mg Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe rheumatoid arthritis if other treatments have already been tried and have not worked. It is not a first-line treatment. It works by reducing the body's immune system, this decreases swelling, reduces pain, stiffness, and improves function. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. Do not take more than you should. It may take several months to become fully effective. In Treatment of Psoriasis Biotrexate 2.5mg Tablet belongs to a group of medicines called antimetabolites. It may be used to treat severe psoriasis when other treatments have not worked. Psoriasis is a condition where the skin cells in the body grow too quickly. Biotrexate 2.5mg Tablet works by killing these fast-growing cells. It is potent and very toxic medicine and you should discuss the risks and benefits with your doctor. Take it exactly as prescribed and for as long as it is prescribed to get the most benefit. DO NOT take more than you should. It may take several months to become fully effective. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects

The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.

How to use

Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Biotrexate 2.5mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.Follow your doctor's guidance regarding the dose and duration of this medication. Ingest it without breaking or crushing. Do not chew, crush or break it. Biotrexate 2.5mg Tablet can be taken it with or without food, although it's advisable to take it consistently at the same time.

How it works

Biotrexate 2.5mg Tablet is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of the body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.Biotrexate 2.5mg Tablet is an immunosuppressant. In rheumatoid arthritis, it works by decreasing the activity of the body's immune system. This decreases swelling, reduces pain and stiffness, and improves function. In psoriasis, it works by slowing down the rapid growth of skin cells.

Alcohol

Caution: It is important to consult your doctor regarding alcohol consumption while taking Biotrexate 2.5mg Tablet .Caution: It is important to consult your doctor regarding alcohol consumption while taking Biotrexate 2.5mg Tablet .

Pregnancy

Not Safe: Biotrexate 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.Not Safe: Biotrexate 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

Not Safe: Biotrexate 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.Not Safe: Biotrexate 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

Not Safe: Biotrexate 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.Not Safe: Biotrexate 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

Caution Advised: Biotrexate 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Biotrexate 2.5mg Tablet may be needed. Doctor consultation is advised. Regular monitoring of kidney function test is advised while you are taking this medicine.Caution Advised: Biotrexate 2.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Biotrexate 2.5mg Tablet may be needed. Doctor consultation is advised. Regular monitoring of kidney function test is advised while you are taking this medicine.

Liver

Caution Advised: Biotrexate 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Biotrexate 2.5mg Tablet may be needed. Doctor consultation is advised. Use of Biotrexate 2.5mg Tablet is not recommended in patients with severe liver disease.Caution Advised: Biotrexate 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Biotrexate 2.5mg Tablet may be needed. Doctor consultation is advised. Use of Biotrexate 2.5mg Tablet is not recommended in patients with severe liver disease.

What if I forget to take it?

If a dose of Biotrexate 2.5mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.If a dose of Biotrexate 2.5mg Tablet is missed, take it promptly. However, if your next dose is approaching, skip the missed dose and resume your regular schedule. Avoid doubling the dose.

Manufacturer Address

BIOCHEM PHARMA, LG 113 / A, Xth Central Mall, Mahavir Nagar, 90ft Road, Next to D Mart, Kandivali - West, Mumbai - 400067.

Frequently asked questions

Are both Biotrexate & Methoquest medicines exactly the same?
Yes, both medicines have the same salt composition, dosage, and effectiveness. They work the same way in your body. The only difference is the brand — and Methoquest option is much more affordable without compromising on quality
Can Biotrexate 2.5mg Tablet affect fertility?
Yes, Biotrexate 2.5mg Tablet can impact fertility in both genders, potentially reducing sperm count in males and causing menstrual irregularities in females. These effects are reversible after stopping the medication.
Can Biotrexate 2.5mg Tablet cause mouth ulcers?
Yes, Biotrexate 2.5mg Tablet can cause mouth ulcers and soreness. Taking folic acid may help reduce these ulcers. Consult your doctor about possibly reducing the dose to further alleviate the issue.
Why do I have to take folic acid with Biotrexate 2.5mg Tablet?
Folic acid is essential for cell production, and Biotrexate 2.5mg Tablet can lower folic acid levels. It helps mitigate side effects like mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia, and liver issues.
Can Biotrexate 2.5mg Tablet use make me more prone to infections?
Biotrexate 2.5mg Tablet may weaken your immune system, increasing the risk of serious infections, including rare lung infections. Use with caution if you have an active infection.
Why do I need to take regular blood tests while taking Biotrexate 2.5mg Tablet?
Regular blood tests allow your doctor to monitor your response to Biotrexate 2.5mg Tablet and check for side effects, including liver function and blood counts. Additional tests may be ordered based on results.
What to do if I am planning to become pregnant and my husband is taking Biotrexate 2.5mg Tablet?
Avoid pregnancy while your husband is on Biotrexate 2.5mg Tablet and for at least 3 months after therapy, as it may cause serious fetal abnormalities.

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References

  • Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46

  • Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90

  • Methotrexate (19 Apr. 2023)

  • Methotrexate (19 Apr. 2023)

  • Methotrexate (19 Apr. 2023)

  • Walfish AE, Companioni RA. Drugs for Inflammatory Bowel Disease (19 Apr. 2023)

  • Crohn's & Colitis, UK. Methotrexate (19 Apr. 2023)

  • Methotrexate (26 Feb. 2025)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.