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Trazumab 440mg Solution for Infusion

Trazumab 440mg Solution for Infusion

Emcure Pharmaceuticals Ltd.

Vial of 1 Solution

54,662.7

54,662.7 / Unit
Our Recommendation

Our Recommendation

Hervycta 440mg Injection 1s

Hervycta 440mg Injection 1s

Dr. Reddy's Laboratories Ltd.
Vial of 1 units

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Long Expiry

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Used In

Breast cancer / Stomach cancer

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More About Trazumab

Trazumab
Hervycta
Benefits
Side Effects
How to use
How it works
What if I forget to take it?
Manufacturer Address

Benefits

Breast cancer / Stomach cancerBreast cancer / Stomach cancer

In Breast cancer Trazumab 440mg Solution for Infusion is used to treat breast cancer when other medicines have failed to show significant improvement. It helps to stop cancer growth and further spread and relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. This medicine is given as an injection by a doctor or nurse. Follow your doctor?s instructions carefully to get the most benefit. In Stomach cancer Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Trazumab 440mg Solution for Infusion helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor?s instructions carefully to get the most benefit.In Breast cancer Trazumab 440mg Solution for Infusion is used to treat breast cancer when other medicines have failed to show significant improvement. It helps to stop cancer growth and further spread and relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipple or changes in the shape or texture of the breast. This medicine is given as an injection by a doctor or nurse. Follow your doctor?s instructions carefully to get the most benefit. In Stomach cancer Stomach cancer also known as gastric cancer, may occur in the inner lining (called mucosa) of the stomach or in the walls of the stomach. These are of various kinds depending on the origin, affected area and severity of the cancer. Trazumab 440mg Solution for Infusion helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor?s instructions carefully to get the most benefit.

Side Effects

The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.The majority of side effects typically do not necessitate medical intervention. and disappear as your body adjusts to the medicine. Doctor consultation is advised if they persist or if you're worried about them.

How to use

Your doctor or nurse will give you this medicine. Kindly do not self-administer.Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How it works

Trazumab 440mg Solution for Infusion is a recombinant Ig G1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.Trazumab 440mg Solution for Infusion is a recombinant Ig G1 monoclonal antibody. It works against the HER2 (human epidermal growth factor receptor protein) receptors which are responsible for the over-proliferation of cancer cells in breast cancer and stomach cancer cells. It destroys the cancer cells by inhibiting HER2. It also inhibits various cancer-causing downstream signaling pathways.

Alcohol

Unsafe: Avoid consuming alcohol with Trazumab 440mg Solution for Infusion as it is deemed unsafe.Unsafe: Avoid consuming alcohol with Trazumab 440mg Solution for Infusion as it is deemed unsafe.

Pregnancy

Seek medical advice from your doctor: Trazumab 440mg Solution for Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.Seek medical advice from your doctor: Trazumab 440mg Solution for Infusion is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Doctor consultation is advised.

Breast feeding

Seek medical advice from your doctor: Trazumab 440mg Solution for Infusion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.Seek medical advice from your doctor: Trazumab 440mg Solution for Infusion is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Seek medical advice from your doctor: It is not known whether Trazumab 440mg Solution for Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.Seek medical advice from your doctor: It is not known whether Trazumab 440mg Solution for Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

Safe when prescribed by an expert: Trazumab 440mg Solution for Infusion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trazumab 440mg Solution for Infusion may not be needed in these patients. Doctor consultation is advised.Safe when prescribed by an expert: Trazumab 440mg Solution for Infusion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Trazumab 440mg Solution for Infusion may not be needed in these patients. Doctor consultation is advised.

Liver

Seek medical advice from your doctor: There is limited information available on the use of Trazumab 440mg Solution for Infusion in patients with liver disease. Doctor consultation is advised.Seek medical advice from your doctor: There is limited information available on the use of Trazumab 440mg Solution for Infusion in patients with liver disease. Doctor consultation is advised.

What if I forget to take it?

If a dose of Trazumab 440mg Solution for Infusion is missed, it's advisable to consult your doctor.If a dose of Trazumab 440mg Solution for Infusion is missed, it's advisable to consult your doctor.

Manufacturer Address

255/2, Hinjawadi, Pune - 411057, India

Frequently asked questions

Are both Trazumab & Hervycta medicines exactly the same?
Yes, both medicines have the same salt composition, dosage, and effectiveness. They work the same way in your body. The only difference is the brand — and Hervycta option is much more affordable without compromising on quality
How frequently heart investigations are required?
Heart investigations should be conducted at the start of treatment, repeated every 3 months during treatment, and every 6 months after treatment for up to 24 months. Patients with existing heart issues will require checks every 12 weeks.
Why has my doctor advised for investigations of heart?
Investigations are necessary because Trazumab 440mg Solution for Infusion, when used with anthracycline anti-cancer medicines (e.g., doxorubicin), may negatively impact heart health. Your doctor will monitor your heart health before and during treatment.
How long should Trazumab 440mg Solution for Infusion be taken?
Trazumab 440mg Solution for Infusion should be taken for 1 year or until disease recurrence in patients with early breast cancer. Treatment should not extend beyond 1 year.
What are the serious side effects of Trazumab 440mg Solution for Infusion?
Serious side effects of Trazumab 440mg Solution for Infusion include sore throat, fever, chills, excessive tiredness, pale skin, nosebleeds, unusual bruising or bleeding, stomach pain, seizures, hallucinations, muscle cramps, spasms, nausea, vomiting, loss of appetite, fatigue, rapid heartbeat, discoloration of urine, decreased urination, difficulty urinating, and signs of infection. Contact your doctor immediately if you experience any of these symptoms.
Is fasting required before administering Trazumab 440mg Solution for Infusion?
Fasting is not required before administering Trazumab 440mg Solution for Infusion. It should be given under the supervision of a qualified healthcare professional experienced in cancer chemotherapy.
How long after Trazumab 440mg Solution for Infusion therapy can I get pregnant?
Women of child-bearing age should use effective contraception during Trazumab 440mg Solution for Infusion therapy and for 7 months after treatment. You can plan your pregnancy after this period.
Can Trazumab 440mg Solution for Infusion be given to HER2 negative cancer patients?
Trazumab 440mg Solution for Infusion is not suitable for HER2 negative cancer patients, as it targets the HER2 protein found in HER2 positive patients. It will not be effective in patients without HER2.
How is Trazumab 440mg Solution for Infusion given, intravenously or intramuscularly?
Trazumab 440mg Solution for Infusion can be administered as an intravenous infusion or a subcutaneous injection. Ensure the correct formulation is used as prescribed, as the intravenous formulation is not for subcutaneous use. Your doctor may switch between the two methods if appropriate.

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References

  • Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1737

  • Lake DF, Briggs AD, Akporiaye ET. Immunopharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 978

  • Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1390-91

  • Trastuzumab. South San Francisco, California: Genentech, Inc.; 1998 (27 Mar. 2019)

  • Drugs and Lactation Database (LactMed) (19 Feb. 2020)

Disclaimer

PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.