Ado-trastuzumab emtansine

Uses

Ado-trastuzumab emtansine is used in the treatment of breast cancer and metastatic breast cancer. It is indicated for certain types of breast cancer that are positive for human epidermal growth factor receptor 2 (HER-2) and have spread to other organs, particularly in cases that have not responded to other cancer therapies.

How it Works

How Ado-trastuzumab emtansine works Ado-trastuzumab emtansine is an anti-cancer medication. It binds to HER2 receptors on breast cancer cells, marking them for destruction by the body's immune system. Additionally, it enters the cancer cells to release a chemotherapy agent (emtansine), inhibiting their growth and division.

Side Effects

Common side effects of Ado-trastuzumab emtansine include tiredness, nausea, musculoskeletal pain (bone, muscle, or joint), bleeding, low blood platelets, headache, liver disorder, constipation, and nosebleeds.

Expert Advice

Ado-trastuzumab emtansine is administered via intravenous infusion under the supervision of a doctor.
Do not skip any doses and complete the treatment course as prescribed by your doctor.
Your doctor may assess your liver function prior to initiating treatment and continue to monitor it regularly thereafter.
Notify your doctor if you experience any of the following symptoms:
- Yellowing of the eyes or skin
- Dark urine
- Stomach pain
Women who could become pregnant should use a reliable method of contraception to prevent pregnancy while on this medication.
Regular monitoring of heart function (such as echocardiograms) and blood tests to assess blood cell levels may be recommended before starting treatment and at regular intervals during treatment with Ado-trastuzumab emtansine.

Other Combinations

Frequently asked questions

How is Ado-trastuzumab emtansine different?

Ado-trastuzumab emtansine combines the HER2-targeted antibody trastuzumab with the chemotherapy drug emtansine, delivering the chemotherapy specifically to HER2-positive cells while minimizing damage to normal cells.

What is the use of Ado-trastuzumab emtansine?

Ado-trastuzumab emtansine is used to treat HER2-positive metastatic breast cancer after prior treatment with trastuzumab and a taxane.

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