Seraz D 50mg/10mg Tablet

Seraz D 50mg 10mg Tablet is a dual-action tablet combining the potent pain relief and anti-inflammatory properties of Diclofenac with the anti-swelling and anti-oedema action of the enzyme Serratiopeptidase. This combination is highly effective for rapidly reducing pain, inflammation, and associated swelling (oedema) caused by musculoskeletal injuries, post-operative trauma, or inflammatory conditions. The addition of Serratiopeptidase helps dissolve inflammatory debris, leading to better circulation and faster resolution of swelling, thereby enhancing the overall therapeutic outcome.

Seraz D 50mg 10mg Tablet is an oral tablet formulated for the effective management of acute pain and inflammation. It combines two active ingredients that work through complementary mechanisms to provide both rapid relief and enhanced recovery.

Diclofenac is a widely used Non‑Steroidal Anti‑Inflammatory Drug (NSAID). It acts by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. Prostaglandins are chemical mediators that trigger pain, fever, and inflammation. By reducing their synthesis, Diclofenac delivers fast and reliable relief from pain and swelling.

Serratiopeptidase is a proteolytic enzyme originally derived from bacteria in the silkworm gut. It functions as a mucolytic and anti‑oedematous agent. Serratiopeptidase helps break down inflammatory by‑products such as fibrin, bradykinin, and damaged tissue that accumulate at sites of injury. This action reduces the thickness of inflammatory exudates, promotes drainage, and accelerates the resolution of swelling and bruising.

Together, Diclofenac and Serratiopeptidase act synergistically. While Diclofenac addresses pain and inflammation directly, Serratiopeptidase clears inflammatory debris and improves tissue penetration of the NSAID. This dual approach ensures faster symptom relief, better control of swelling, and more efficient recovery.

Seraz D 50mg 10mg Tablet is indicated for the short-term treatment of inflammatory conditions accompanied by pain and swelling:

• Post-Traumatic Swelling: Management of pain and swelling following soft tissue injuries (e.g., sprains, strains, fractures).

• Post-Operative Inflammation: Relief of pain, tenderness, and oedema following dental, minor surgical, or orthopaedic procedures.

• Musculoskeletal Disorders: Pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute gout.

• Infectious Inflammation: Adjunct therapy to reduce swelling in conditions like pharyngitis, sinusitis, or otitis media (as part of a full treatment regimen, typically including antibiotics).

• Dual-Action Relief: Combines powerful pain relief (Diclofenac) with direct anti-swelling action (Serratiopeptidase), providing comprehensive relief that simple NSAIDs alone may not offer.

• Accelerated Healing: Serratiopeptidase helps clear inflammatory debris and exudates, improving lymphatic drainage and microcirculation to the injured area, which promotes faster recovery and resolution of swelling.

• Potent Anti-Inflammatory Effect: Diclofenac is a strong inhibitor of prostaglandin synthesis, rapidly bringing down acute inflammation.

• Improved Drug Penetration: By breaking down viscous inflammatory material, Serratiopeptidase may enhance the penetration of Diclofenac into the inflamed tissue.

Seraz D 50mg 10mg Tablet is generally well-tolerated when taken as prescribed, but it may cause some side effects. Most are mild and short‑lived, while more serious reactions are less common but require medical attention.

Common side effects (usually mild and short‑lived):

• Stomach upset, nausea, or indigestion

• Headache or dizziness

• Mild skin rash or itching

• Less common side effects (seek medical advice if persistent or severe):

• Gastrointestinal Bleeding/Ulcers: Black or bloody stools, severe stomach pain, or vomiting blood.

• Cardiovascular Events: Chest pain, sudden weakness, or shortness of breath (especially in patients with pre-existing heart conditions).

• Severe Allergic Reaction (Anaphylaxis): Swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing.

• Liver Problems: Yellowing of the skin or eyes (jaundice), dark urine, or persistent nausea.

• Kidney Problems: Changes in the amount of urine, or swelling in the feet/ankles.

• Patients should immediately stop the medication and consult a doctor if any serious side effects occur.

• Dosage: Strictly follow the dose and duration prescribed by your doctor. This medicine should be used for the shortest possible duration to manage acute symptoms.

• Administration: Swallow the tablet whole with a glass of water.

• Timing: It is generally recommended to take Seraz D 50mg 10mg Tablet with food or milk to minimise the risk of stomach irritation.

• Do Not Crush or Chew: The tablet must be swallowed whole to ensure the ingredients are released appropriately and to protect the stomach lining.

• Take with Food: Always take Seraz D 50mg 10mg Tablet with a full meal or a snack to shield your stomach from Diclofenac's irritating effects.

• Watch for Bleeding: Be vigilant for signs of stomach irritation or bleeding, such as black, tarry stools, or persistent indigestion. Report these immediately to your doctor.

• Limit Duration: This medicine is for acute pain and swelling. Do not use it long-term unless specifically directed and monitored by a healthcare professional.

• Enzyme Action: Serratiopeptidase may make you notice a slight thinning of mucus (if you have concurrent cold/sinus issues), which is a normal part of its action.

• Store at room temperature (typically below 30 °C / 86 °F).

• Keep the tablets in the original packaging to protect them from moisture and light.

• Keep out of the sight and reach of children.

• Do not use the medicine after the expiry date.

Food: Taking the tablet with food is mandatory to reduce gastrointestinal irritation. Alcohol: AVOID or limit alcohol consumption. Alcohol dramatically increases the risk of stomach irritation, ulcers, and gastrointestinal bleeding caused by Diclofenac.

• Other NSAIDs or Aspirin: DO NOT USE concurrently, as this drastically increases the risk of GI bleeding without providing additional benefit.

• Anticoagulants (e.g., Warfarin, Heparin): Increases the risk of severe bleeding. Requires very close monitoring of INR/blood clotting times.

• Corticosteroids (e.g., Prednisone): Increases the risk of gastrointestinal ulcers and bleeding.

• Diuretics and ACE Inhibitors: Diclofenac can reduce the effectiveness of these blood pressure medications and may increase the risk of kidney problems.

• Lithium or Methotrexate: Diclofenac can increase the blood levels and potential toxicity of these drugs.

• Peptic Ulcer Disease/GI Bleeding: CONTRAINDICATED due to the high risk of severe bleeding caused by Diclofenac.

• Cardiovascular Disease (Heart Attack, Stroke, Congestive Heart Failure): Use with EXTREME CAUTION. Diclofenac is associated with an increased risk of serious cardiovascular thrombotic events.

• Asthma (Aspirin-sensitive): Diclofenac can trigger acute asthma attacks (bronchospasm) in sensitive patients.

• Coagulation Disorders: Serratiopeptidase has mild fibrinolytic properties, and Diclofenac impairs platelet function, increasing the risk of bleeding.

The typical adult dose is one tablet (Diclofenac 50mg + Serratiopeptidase 10mg) taken two to three times daily, as prescribed by the doctor. The dosage is determined by the severity of pain and inflammation, and should not exceed the maximum daily dose set by your physician.

If you take more Seraz D 50mg 10mg Tablet than your doctor prescribed, it can be harmful. Too much of this medicine may cause stomach pain, nausea, vomiting, diarrhoea, or even bleeding in the stomach. You might also feel dizzy, very sleepy, confused, or have chest pain and trouble breathing. In some cases, it can affect the liver or kidneys, leading to yellowing of the skin or eyes, swelling in the legs, or reduced urine output.

If you think you have taken too much, get medical help right away. Do not try to treat yourself at home or wait for the symptoms to go away. Take the medicine pack or prescription details with you so doctors know exactly what you took.

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for the missed one.