Substitute of Sisglim M 1mg/500mg Tablet PR
Salt Composition
Glimepiride 1mg + Metformin 500mg
Primary Use
How Glimepiride and Metformin Work Glimepiride and Metformin is a combination of two antidiabetic medications: Glimepiride and Metformin.
Original Brand
Millennial Pharmaceuticals Pvt. Ltd.
Standard Price
Syed Jommy Abbas, Pharmacist
B. Pharma
Devika Rani, MBBS
MBBS
Looking for an affordable alternative to Sisglim M 1mg/500mg Tablet PR? The substitutes below contain the exact same active ingredients Glimepiride + Metformin and offer identical therapeutic benefits.
Top Substitutes by Savings
All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Sisglim M 1mg/500mg Tablet PR.
Medicine NAME
PRICE
Glimp M 1/500mg Tablet SR 10s
Biochem Pharmaceutical Industries
MRP: ₹106.2 (10 Tablets)
₹10.6/unit
Cost 8% more
Cost 8% more
View DetailsGlimnew M1 Tablet PR 10s
Genexwell Biotech
MRP: ₹70 (10 Tablets)
₹7/unit
Cost 43% more
Cost 43% more
View DetailsGlimestar M 1/500mg Tablet 10s
Mankind Pharmaceuticals Ltd.
MRP: ₹74.9 (10 Tablets)
₹7.5/unit
Cost 53% more
Cost 53% more
View DetailsIsryl M 1/500mg Tablet PR 15s
Systopic Laboratories Pvt. Ltd.
MRP: ₹45 (15 Tablets)
₹3/unit
39% Lower Price
39% Lower Price
View DetailsZoryl M1 1/500mg Tablet PR 20s
Intas Pharmaceuticals Ltd.
MRP: ₹278.4 (20 Tablets)
₹13.9/unit
Cost 184% more
Cost 184% more
View DetailsProtoglim M1 Tablet PR 10s
Empower Life Sciences
MRP: ₹75 (10 Tablets)
₹7.5/unit
Cost 53% more
Cost 53% more
View DetailsGemer 1/500mg Tablet PR 15s
Sun Pharmaceutical Industries Ltd.
MRP: ₹167.8 (15 Tablets)
₹11.2/unit
Cost 128% more
Cost 128% more
View DetailsMaglimet 1mg Tablet PR 10s
Magnomed Pharmaceuticals Llp
MRP: ₹80 (10 Tablets)
₹8/unit
Cost 63% more
Cost 63% more
View DetailsGluconorm G 1 1/500mg Tablet PR 15s
Lupin Ltd.
MRP: ₹255.5 (15 Tablets)
₹17/unit
Cost 248% more
Cost 248% more
View DetailsAmaryl M 1 1/500mg Tablet PR 20s
Sanofi India Ltd.
MRP: ₹303 (20 Tablets)
₹15.2/unit
Cost 209% more
Cost 209% more
View DetailsGeminor M 1/500mg Tablet PR 15s
Macleods Pharmaceuticals Pvt. Ltd.
MRP: ₹167.1 (15 Tablets)
₹11.1/unit
Cost 127% more
Cost 127% more
View DetailsMetafort G1 CP Tablet PR
Eris Lifesciences Ltd.
MRP: ₹241.9 (30 Tablets)
₹8.1/unit
Cost 65% more
Cost 65% more
View DetailsAzulix 1/500mg MF Tablet PR 15s
Torrent Pharmaceuticals Ltd.
MRP: ₹186.8 (15 Tablets)
₹12.5/unit
Cost 154% more
Cost 154% more
View DetailsSwitglim M 1/500mg Tablet 15s
Akumentis Healthcare Ltd.
MRP: ₹72.5 (15 Tablets)
₹4.8/unit
1% Lower Price
1% Lower Price
View DetailsDuopil 1/500mg Tablet PR 10s
Aristo Pharmaceuticals Pvt. Ltd.
MRP: ₹74.9 (10 Tablets)
₹7.5/unit
Cost 53% more
Cost 53% more
View DetailsGlyciphage G 1/500mg Tablet PR 10s
Franco-Indian Pharmaceuticals Pvt. Ltd.
MRP: ₹96.2 (10 Tablets)
₹9.6/unit
Cost 96% more
Cost 96% more
View DetailsGlucoris M1 1/500mg Tablet PR 15s
Orris Pharmaceuticals
MRP: ₹92.8 (15 Tablets)
₹6.2/unit
Cost 26% more
Cost 26% more
View DetailsGlimgill M 1/500mg Tablet 10s
Ganik Pharma
MRP: ₹64.6 (10 Tablets)
₹6.5/unit
Cost 32% more
Cost 32% more
View DetailsGliprez MF 1/500mg Tablet 10s
Snig Pharmaceuticals Pvt. Ltd.
MRP: ₹59.1 (10 Tablets)
₹5.9/unit
Cost 21% more
Cost 21% more
View DetailsZiglim M1 1/500mg Tablet PR 15s
FDC Ltd.
MRP: ₹71.9 (15 Tablets)
₹4.8/unit
2% Lower Price
2% Lower Price
View DetailsUses
How Glimepiride and Metformin Work Glimepiride and Metformin is a combination of two antidiabetic medications: Glimepiride and Metformin.
How it Works
Common side effects of Glimepiride and Metformin include nausea, diarrhea, headache, upper respiratory tract infection, dizziness, and flatulence.
Safety Advice
Pregnancy
CONTRAINDICATED.
- Oral antidiabetic agents are generally not recommended during pregnancy due to the risk of fetal hypoglycemia.
- Treatment for diabetes during pregnancy is typically transitioned to insulin therapy. Consult a specialist immediately if you are pregnant or planning conception.
Breastfeeding
CONSULT YOUR DOCTOR.
Both Glimepiride and Metformin may be excreted into breast milk. Due to the potential risk of hypoglycemia in the infant, the decision to continue the drug must be made by carefully weighing the mother's health needs against the infant’s safety.
Alcohol
STRICT AVOIDANCE.
Alcohol consumption is highly discouraged. It significantly increases the risk of hypoglycemia (enhancing Glimepiride's effect) and, critically, increases the risk of the life-threatening condition Lactic Acidosis (a severe
Driving
CAUTION.
- The risk of hypoglycemia (dizziness, shaking, confusion) from Glimepiride can impair driving ability.
- Patients should learn to recognise and treat early signs of low blood sugar and carry a source of fast-acting sugar to mitigate risks before driving.
Diet & Lifestyle
- Consistent Carbohydrate Intake: Never skip meals, as this greatly increases the risk of Glimepiride-induced hypoglycemia. Maintain a regular meal schedule with consistent carbohydrate content.
- Hydration: Maintain adequate hydration to support kidney function, which is necessary for the safe clearance of Metformin.
Is it Safe to Switch?
The Same Salt and Strenght Rule
The core of any medication is its active ingredient, or "salt." Whether you buy the original Sisglim M 1mg/500mg Tablet PR or a substitute, the active ingredient Glimepiride + Metformin is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.
When not to switch
While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:
Specific Allergies:You are sensitive to certain dyes or lactose fillers.
Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).
Crucial Steps Before Changing
Verify the Strength & Release Profile
Double-check your prescription for two critical details before switching brands:
Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Consult Your Physician
Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.
Myths vs. Facts About Generic Medicines
Don't let misinformation stop you from saving money. Here is the truth about generic medications.
Cheaper medicines are lower quality and take longer to work.
Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.
Generic drugs cause more side effects or stomach issues.
The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.
Generic companies skip safety testing to save money.
False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.