PlatinumRx

Substitute of Refdux 400mg Tablet

Refdux 400mg Tablet

Salt Composition

Rifaximin 400mg

Primary Use

Rifaximin is used in the treatment of hepatic encephalopathy.

Original Brand

Nydux Pharma

Standard Price

₹360.9 MRP ₹360.9 (10 Tablets)
₹36.1/unit
View Refdux 400mg Tablet Details
Written by:

Sahinur Parbin

B pharmacy

Devika Rani
Reviewed by:

Devika Rani, MBBS

MBBS

Last updated on: 13 May 2026
Always consult your doctor before switching your medication to ensure the alternative aligns with your specific health profile.

Looking for an affordable alternative to Refdux 400mg Tablet? The substitutes below contain the exact same active ingredients Rifaximin and offer identical therapeutic benefits.

Top Substitutes by Savings

All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Refdux 400mg Tablet.

Rifaxigress 200 Tablet

La Renon Healthcare Pvt. Ltd.

MRP: ₹149.1 (10 Tablets)

₹14.9/unit

59% Lower Price

59% Lower Price

View Details

Rifaxemania 200mg Tablet 10s

Steris Healthcare Pvt. Ltd.

Maximum Savings

MRP: ₹259 (10 Tablets)

₹25.9/unit

64% Lower Price

64% Lower Price

View Details

Gifaxin 200mg Tablet 10s

Aristo Pharmaceuticals Pvt. Ltd.

MRP: ₹185.2 (10 Tablets)

₹18.5/unit

49% Lower Price

49% Lower Price

View Details

Nordys 200mg Tablet 10s

Micro Labs Ltd.

MRP: ₹184.6 (10 Tablets)

₹18.5/unit

49% Lower Price

49% Lower Price

View Details

Rifakem 200mg Tablet 10s

Alkem Laboratories Ltd.

MRP: ₹194.1 (10 Tablets)

₹19.4/unit

46% Lower Price

46% Lower Price

View Details

Rifaximax 200 Tablet

Zuventus Healthcare Ltd.

MRP: ₹196.2 (10 Tablets)

₹19.6/unit

46% Lower Price

46% Lower Price

View Details

Rifastop 200mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹198.5 (10 Tablets)

₹19.9/unit

45% Lower Price

45% Lower Price

View Details

Rifasmart 200mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹198.5 (10 Tablets)

₹19.9/unit

45% Lower Price

45% Lower Price

View Details

Rifaset 200mg Tablet 10s

Macleods Pharmaceuticals Pvt. Ltd.

MRP: ₹206.4 (10 Tablets)

₹20.6/unit

43% Lower Price

43% Lower Price

View Details

Ciboz 200mg Tablet 10s

Zydus Cadila

MRP: ₹230.3 (10 Tablets)

₹23/unit

36% Lower Price

36% Lower Price

View Details

Rafle 200mg Tablet 10s

Alembic Pharmaceuticals Ltd.

MRP: ₹232 (10 Tablets)

₹23.2/unit

36% Lower Price

36% Lower Price

View Details

Rifarex 200mg Tablet

Tas Med India Pvt. Ltd.

MRP: ₹232.9 (10 Tablets)

₹23.3/unit

35% Lower Price

35% Lower Price

View Details

Sibofix 200mg Tablet 10s

Dr. Reddy's Laboratories Ltd.

MRP: ₹235.8 (10 Tablets)

₹23.6/unit

35% Lower Price

35% Lower Price

View Details

Rifaxigyl 200mg Tablet 10s

Medley Pharmaceuticals

MRP: ₹239.1 (10 Tablets)

₹23.9/unit

34% Lower Price

34% Lower Price

View Details

Zimigut 200mg Tablet 10s

Intas Pharmaceuticals Ltd.

MRP: ₹244.2 (10 Tablets)

₹24.4/unit

32% Lower Price

32% Lower Price

View Details

Lomotil RF 200mg Tablet 10s

RPG Life Sciences Ltd.

PlatinumRx Top Choice

MRP: ₹250 (10 Tablets)

₹25/unit

31% Lower Price

31% Lower Price

View Details

Torfix 200mg Tablet 10s

Torrent Pharmaceuticals Ltd.

MRP: ₹249.4 (10 Tablets)

₹24.9/unit

31% Lower Price

31% Lower Price

View Details

Rifagut 200mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

MRP: ₹257 (10 Tablets)

₹25.7/unit

29% Lower Price

29% Lower Price

View Details

Rcifax 200mg Tablet 10s

Lupin Ltd.

MRP: ₹284 (10 Tablets)

₹28.4/unit

21% Lower Price

21% Lower Price

View Details

Rifayes 400mg Tablet 10s

Dr. Morepen Ltd.

PlatinumRx Top Choice

MRP: ₹435.5 (10 Tablets)

₹43.6/unit

35% Lower Price

35% Lower Price

View Details

Rifabiz 400mg Tablet 10s

Alniche Life Sciences Pvt. Ltd.

MRP: ₹309.7 (10 Tablets)

₹31/unit

14% Lower Price

14% Lower Price

View Details

Setsibo 400mg Tablet 10s

Syndicate Life Sciences Pvt. Ltd.

MRP: ₹317.8 (10 Tablets)

₹31.8/unit

12% Lower Price

12% Lower Price

View Details

Sibocure 400 Tablet

Saffron Formulations Pvt. Ltd.

MRP: ₹318.8 (10 Tablets)

₹31.9/unit

12% Lower Price

12% Lower Price

View Details

Gifaxin 400mg Tablet 10s

Aristo Pharmaceuticals Pvt. Ltd.

MRP: ₹329.1 (10 Tablets)

₹32.9/unit

9% Lower Price

9% Lower Price

View Details

Xifarix 400mg Tablet

Sinsan Pharmaceuticals

MRP: ₹330 (10 Tablets)

₹33/unit

9% Lower Price

9% Lower Price

View Details

Nordys 400mg Tablet 10s

Micro Labs Ltd.

MRP: ₹346.8 (10 Tablets)

₹34.7/unit

4% Lower Price

4% Lower Price

View Details

Rifaxigress 400mg Tablet 10s

La Renon Healthcare Pvt. Ltd.

MRP: ₹352.5 (10 Tablets)

₹35.3/unit

2% Lower Price

2% Lower Price

View Details

Rifasmart 400mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹355.3 (10 Tablets)

₹35.5/unit

2% Lower Price

2% Lower Price

View Details

Dirifa 400mg Tablet 10s

Abbott Healthcare Pvt. Ltd.

MRP: ₹356.7 (10 Tablets)

₹35.7/unit

1% Lower Price

1% Lower Price

View Details

Rifayes 550mg Tablet 10s

Dr. Morepen Ltd.

PlatinumRx Top Choice

MRP: ₹575 (10 Tablets)

₹57.5/unit

14% Lower Price

14% Lower Price

View Details

Rifakem 400mg Tablet 10s

Alkem Laboratories Ltd.

MRP: ₹389.1 (10 Tablets)

₹38.9/unit

Cost 8% more

Cost 8% more

View Details

Rifastop 400mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹390.8 (10 Tablets)

₹39.1/unit

Cost 8% more

Cost 8% more

View Details

Rifabiz 550 Tablet 10s

Alniche Life Sciences Pvt. Ltd.

MRP: ₹396 (10 Tablets)

₹39.6/unit

Cost 10% more

Cost 10% more

View Details

Lomotil RF 400mg Tablet 10s

RPG Life Sciences Ltd.

PlatinumRx Top Choice

MRP: ₹400 (10 Tablets)

₹40/unit

Cost 11% more

Cost 11% more

View Details

Rifaxigyl 400mg Tablet 10s

Medley Pharmaceuticals

MRP: ₹400.3 (10 Tablets)

₹40/unit

Cost 11% more

Cost 11% more

View Details

Rifarex 400mg Tablet 10s

Tas Med India Pvt. Ltd.

MRP: ₹402.1 (10 Tablets)

₹40.2/unit

Cost 11% more

Cost 11% more

View Details

Ciboz 400mg Tablet 10s

Zydus Cadila

MRP: ₹412.1 (10 Tablets)

₹41.2/unit

Cost 14% more

Cost 14% more

View Details

Rifasmart 550mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹417.2 (10 Tablets)

₹41.7/unit

Cost 16% more

Cost 16% more

View Details

Rafle 400mg Tablet 10s

Alembic Pharmaceuticals Ltd.

MRP: ₹420.5 (10 Tablets)

₹42.1/unit

Cost 16% more

Cost 16% more

View Details

Gifaxin 550mg Tablet 10s

Aristo Pharmaceuticals Pvt. Ltd.

MRP: ₹440 (10 Tablets)

₹44/unit

Cost 22% more

Cost 22% more

View Details

Xifarix 550 Tablet

Sinsan Pharmaceuticals

MRP: ₹442.5 (10 Tablets)

₹44.3/unit

Cost 23% more

Cost 23% more

View Details

Rifagut 400mg Tablet 10s

Sun Pharmaceutical Industries Ltd.

MRP: ₹450 (10 Tablets)

₹45/unit

Cost 25% more

Cost 25% more

View Details

Rifastop 550mg Tablet 10s

Mankind Pharmaceuticals Ltd.

MRP: ₹458.9 (10 Tablets)

₹45.9/unit

Cost 27% more

Cost 27% more

View Details

Rifaxigress 550mg Tablet 10s

La Renon Healthcare Pvt. Ltd.

MRP: ₹462.2 (10 Tablets)

₹46.2/unit

Cost 28% more

Cost 28% more

View Details

Torfix 400mg Tablet 10s

Torrent Pharmaceuticals Ltd.

MRP: ₹480.3 (10 Tablets)

₹48/unit

Cost 33% more

Cost 33% more

View Details

Rcifax 400mg Tablet 10s

Lupin Ltd.

MRP: ₹484.2 (10 Tablets)

₹48.4/unit

Cost 34% more

Cost 34% more

View Details

Eysirifa 550mg Tablet 10s

Eysys Pharmaceutical Pvt. Ltd.

PlatinumRx Top Choice

MRP: ₹467.8 (10 Tablets)

₹46.8/unit

Cost 30% more

Cost 30% more

View Details

Sibofix 400mg Tablet 10s

Dr. Reddy's Laboratories Ltd.

MRP: ₹487.7 (10 Tablets)

₹48.8/unit

Cost 35% more

Cost 35% more

View Details

Zimigut 400mg Tablet 10s

Intas Pharmaceuticals Ltd.

MRP: ₹483.8 (10 Tablets)

₹48.4/unit

Cost 34% more

Cost 34% more

View Details

Rafle 550 Tablet

Alembic Pharmaceuticals Ltd.

MRP: ₹495.1 (10 Tablets)

₹49.5/unit

Cost 37% more

Cost 37% more

View Details

Uses

Rifaximin is used in the treatment of hepatic encephalopathy.

Side Effects

Common side effects of Rifaximin include dizziness, nausea, peripheral edema, ascites (accumulation of fluid in the abdominal cavity), and fatigue.

How it Works

How Rifaximin works Rifaximin is an antibiotic. In hepatic encephalopathy, it functions by eliminating ammonia-producing bacteria, thereby alleviating symptoms such as agitation, confusion, and muscle issues. In infectious diarrhea, it acts by inhibiting the growth of bacteria responsible for causing diarrhea.

Safety Advice

safety advice icon

PREGNANCY

CONSULT YOUR DOCTOR.

There is limited data on rifaximin use during pregnancy. It should be used only if clearly needed and prescribed by a healthcare professional.

Read More
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BREASTFEEDING

CONSULT YOUR DOCTOR.

Rifaximin may pass into breast milk in small amounts. Use only under medical supervision while breastfeeding.

Read More
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DRIVING

NO INTERACTION.

Rifaximin is not known to affect alertness or the ability to drive or operate machinery.

Read More
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LIVER

CAUTION.

Use with caution in patients with severe liver disease. Advanced hepatic impairment requires close monitoring.

Read More
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KIDNEY

NO INTERACTION.

Minimal absorption means rifaximin generally does not affect kidney function.

Read More
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ALCOHOL

NO INTERACTION.

No known clinically significant interactions with alcohol, though moderation is recommended.

Read More

FOOD

NO INTERACTION.

Can be taken with or without food. Taking with food may help reduce mild stomach discomfort.

Read More
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LIFESTYLE

MODERATE.

Maintaining proper hydration, safe food practices, and good hygiene can support recovery and effectiveness.

Read More

Is it Safe to Switch?

The Same Salt and Strenght Rule

The core of any medication is its active ingredient, or "salt." Whether you buy the original Refdux 400mg Tablet or a substitute, the active ingredient Rifaximin is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.

When not to switch

While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:

Specific Allergies:You are sensitive to certain dyes or lactose fillers.

Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).

Crucial Steps Before Changing

Verify the Strength & Release Profile

Double-check your prescription for two critical details before switching brands:

Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.

Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.

Consult Your Physician

Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.

Myths vs. Facts About Generic Medicines

Don't let misinformation stop you from saving money. Here is the truth about generic medications.

MYTH

Cheaper medicines are lower quality and take longer to work.

FACT

Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.

MYTH

Generic drugs cause more side effects or stomach issues.

FACT

The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.

MYTH

Generic companies skip safety testing to save money.

FACT

False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.

Frequently asked questions

No, the primary side effects are identical. Because substitutes contain the exact same active ingredients, your body reacts to the medication in the exact same way it reacts to the original brand. The only exception is a rare allergy to an inactive filler.