Substitute of Pioplus 1/500/15mg Tablet SR 15s
Salt Composition
Glimepiride 1mg + Metformin 500mg + Pioglitazone 15mg
Primary Use
How Glimepiride, Metformin, and Pioglitazone Work Glimepiride, Metformin, and Pioglitazone is a combination of three antidiabetic medications: Glimepiride, Metformin, and Pioglitazone. They work through different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea that increases the amount of insulin released by the pancreas to lower blood glucose levels. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione that further increases insulin sensitivity.
Original Brand
Systopic Laboratories Pvt. Ltd.
Standard Price
Looking for an affordable alternative to Pioplus 1/500/15mg Tablet SR 15s? The substitutes below contain the exact same active ingredients Glimepiride + Metformin + Pioglitazone and offer identical therapeutic benefits.
Top Substitutes by Savings
All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Pioplus 1/500/15mg Tablet SR 15s.
Medicine NAME
PRICE
Ozomet PG 1/500/15mg Tablet 15s
Ozone Pharmaceuticals Ltd.
MRP: ₹60.3 (15 Tablets)
₹4/unit
27% Lower Price
27% Lower Price
View DetailsTriglynase 1/500/15mg Tablet SR 10s
USV Pvt. Ltd.
MRP: ₹64.2 (10 Tablets)
₹6.4/unit
Cost 17% more
Cost 17% more
View DetailsThe Triglynase 1/500/15mg Tablet 10s
USV Pvt. Ltd.
MRP: ₹64.2 (10 Tablets)
₹6.4/unit
Cost 17% more
Cost 17% more
View DetailsHyglyd GP 1mg Tablet 10s
Ifimed Pharmaceuticals Pvt. Ltd.
MRP: ₹65.6 (10 Tablets)
₹6.6/unit
Cost 19% more
Cost 19% more
View DetailsGlimison MP 1/500/15mg Tablet SR 15s
Unison Pharmaceuticals Pvt. Ltd.
MRP: ₹68.6 (15 Tablets)
₹4.6/unit
17% Lower Price
17% Lower Price
View DetailsAdglim MP 1/500/15mg Tablet 10s
Cadomed Pharmaceuticals Pvt. Ltd.
MRP: ₹69.2 (10 Tablets)
₹6.9/unit
Cost 26% more
Cost 26% more
View DetailsZiglim Plus 1/500/15mg Tablet SR 10s
FDC Ltd.
MRP: ₹70.3 (10 Tablets)
₹7/unit
Cost 28% more
Cost 28% more
View DetailsGlycoheal PG 2/500/15mg Tablet SR 10s
Healing Pharma India Pvt. Ltd.
MRP: ₹124 (10 Tablets)
₹12.4/unit
Cost 13% more
Cost 13% more
View DetailsGlymia 2MP Tablet SR 15s
Chemo Healthcare Pvt. Ltd.
MRP: ₹126 (15 Tablets)
₹8.4/unit
24% Lower Price
24% Lower Price
View DetailsTridart 1/500/15mg Tablet 10s
Anthem Bio Pharma
MRP: ₹75.9 (10 Tablets)
₹7.6/unit
Cost 38% more
Cost 38% more
View DetailsGlimison MP 2/500/15mg Tablet SR 15s
Unison Pharmaceuticals Pvt. Ltd.
MRP: ₹82.7 (15 Tablets)
₹5.5/unit
Cost 0% more
Cost 0% more
View DetailsGeneglim MP 2/500/15mg Tablet 10s
Genezen Healthcare
MRP: ₹80.6 (10 Tablets)
₹8.1/unit
Cost 47% more
Cost 47% more
View DetailsAdglim MP 2/500/15mg Tablet 10s
Cadomed Pharmaceuticals Pvt. Ltd.
MRP: ₹82.8 (10 Tablets)
₹8.3/unit
Cost 51% more
Cost 51% more
View DetailsTriblend 1/500/15mg Tablet 10s
Akesiss Pharma Pvt. Ltd.
MRP: ₹81 (10 Tablets)
₹8.1/unit
Cost 47% more
Cost 47% more
View DetailsAccuglim MP 1/500/15mg Tablet 10s
Cadell Healthcare Pvt. Ltd.
MRP: ₹86 (10 Tablets)
₹8.6/unit
Cost 56% more
Cost 56% more
View DetailsTriglimicer 1/500/15mg Tablet 10s
Retra Life Science Pvt. Ltd.
MRP: ₹85.1 (10 Tablets)
₹8.5/unit
Cost 55% more
Cost 55% more
View DetailsGlimp MP 1/500/15mg SR Tablet 10s
Biochem Pharmaceutical Industries
MRP: ₹145.6 (10 Tablets)
₹14.6/unit
Cost 32% more
Cost 32% more
View DetailsAccuglim MP 2/500/15mg Tablet 10s
Cadell Healthcare Pvt. Ltd.
MRP: ₹88 (10 Tablets)
₹8.8/unit
Cost 60% more
Cost 60% more
View DetailsSureglim Mp1 Tablet 10s
Arist Healthcare
MRP: ₹89.1 (10 Tablets)
₹8.9/unit
Cost 62% more
Cost 62% more
View DetailsSaveglim MP 1/500/15mg Tablet SR 10s
Arist Healthcare
MRP: ₹89.1 (10 Tablets)
₹8.9/unit
Cost 62% more
Cost 62% more
View DetailsGeniride MP 1/500/15mg Tablet SR 10s
Levenr Pharma
MRP: ₹92.8 (10 Tablets)
₹9.3/unit
Cost 69% more
Cost 69% more
View DetailsSwitglim MP 1mg/500mg/15mg Tablet SR
Akumentis Healthcare Ltd.
MRP: ₹92.8 (10 Tablets)
₹9.3/unit
Cost 69% more
Cost 69% more
View DetailsGeniride MP 1/500/15mg Tablet 15s
Levenr Pharma
MRP: ₹92.8 (15 Tablets)
₹6.2/unit
Cost 12% more
Cost 12% more
View DetailsTriglaz 1/500/15mg Tablet 10s
East West Pharma
MRP: ₹95.5 (10 Tablets)
₹9.6/unit
Cost 74% more
Cost 74% more
View DetailsZiglim Plus 2/500/15mg Tablet SR 10s
FDC Ltd.
MRP: ₹96.1 (10 Tablets)
₹9.6/unit
Cost 75% more
Cost 75% more
View DetailsSaveglim MP 2/500/15mg Tablet SR 10s
Arist Healthcare
MRP: ₹93.8 (10 Tablets)
₹9.4/unit
Cost 70% more
Cost 70% more
View DetailsTriblend 2/500/15mg Tablet 10s
Akesiss Pharma Pvt. Ltd.
MRP: ₹96 (10 Tablets)
₹9.6/unit
Cost 75% more
Cost 75% more
View DetailsTridart 2/500/15mg Tablet 10s
Anthem Bio Pharma
MRP: ₹100.3 (10 Tablets)
₹10/unit
Cost 82% more
Cost 82% more
View DetailsTriglynase 2/500/15mg Tablet SR 10s
USV Pvt. Ltd.
MRP: ₹102.4 (10 Tablets)
₹10.2/unit
Cost 86% more
Cost 86% more
View DetailsLaformin GP 1mg Tablet
La Renon Healthcare Pvt. Ltd.
MRP: ₹104.1 (10 Tablets)
₹10.4/unit
Cost 89% more
Cost 89% more
View DetailsCognipride MP 1/500/15mg Tablet 10s
Cognitive Life Sciences Ltd.
MRP: ₹103.1 (10 Tablets)
₹10.3/unit
Cost 88% more
Cost 88% more
View DetailsXadomet GP 1/500/15mg Tablet 10s
Dr. Cure Pharmaceuticals India Pvt. Ltd.
MRP: ₹103.1 (10 Tablets)
₹10.3/unit
Cost 88% more
Cost 88% more
View DetailsGlynamic MP 1mg Tablet 10s
Fusion Healthcare Pvt. Ltd.
MRP: ₹112.5 (10 Tablets)
₹11.3/unit
Cost 105% more
Cost 105% more
View DetailsPioz MF G 1 Tablet SR 10s
USV Pvt. Ltd.
MRP: ₹114.1 (10 Tablets)
₹11.4/unit
Cost 108% more
Cost 108% more
View DetailsPioplus 2/500/15mg Tablet SR 15s
Systopic Laboratories Pvt. Ltd.
MRP: ₹117 (15 Tablets)
₹7.8/unit
Cost 42% more
Cost 42% more
View DetailsPulglim MP 2/500/15mg Tablet 10s
Koplar Healthcare
MRP: ₹117.2 (10 Tablets)
₹11.7/unit
Cost 113% more
Cost 113% more
View DetailsGliminyle MP 1/500/15mg Tablet SR 15s
Erinyle Healthcare Pvt. Ltd.
MRP: ₹119.5 (15 Tablets)
₹8/unit
Cost 45% more
Cost 45% more
View DetailsGeniride MP 2/15/500mg Tablet 15s
Levenr Pharma
MRP: ₹118.1 (15 Tablets)
₹7.9/unit
Cost 43% more
Cost 43% more
View DetailsXadomet GP 2/500/15mg Tablet 10s
Dr. Cure Pharmaceuticals India Pvt. Ltd.
MRP: ₹119 (10 Tablets)
₹11.9/unit
Cost 116% more
Cost 116% more
View DetailsSanomet GP 1/500/15mg Tablet 15s
Sanomed Healthcare
MRP: ₹122 (15 Tablets)
₹8.1/unit
Cost 48% more
Cost 48% more
View DetailsMinglip P 2/500/15mg Tablet SR 10s
Siskan Pharma
MRP: ₹120.9 (10 Tablets)
₹12.1/unit
Cost 120% more
Cost 120% more
View DetailsGlymedus PM 2/500/15mg Tablet 10s
Sedulus Remedies
MRP: ₹121 (10 Tablets)
₹12.1/unit
Cost 120% more
Cost 120% more
View DetailsGzor MP 1/500/15mg Tablet 15s
Lloyd Healthcare Pvt. Ltd.
MRP: ₹123.2 (15 Tablets)
₹8.2/unit
Cost 49% more
Cost 49% more
View DetailsPiopod GM 1 Tablet SR
Torrent Pharmaceuticals Ltd.
MRP: ₹119 (10 Tablets)
₹11.9/unit
Cost 116% more
Cost 116% more
View DetailsGlimwar MP Tablet 10s
Anax Lifescience Pvt. Ltd.
MRP: ₹121.9 (10 Tablets)
₹12.2/unit
Cost 122% more
Cost 122% more
View DetailsGlimivibe MP 2 Tablet SR 10s
Biovibe Drugs
MRP: ₹121.9 (10 Tablets)
₹12.2/unit
Cost 122% more
Cost 122% more
View DetailsMetride 1 Plus Tablet SR
Torrent Pharmaceuticals Ltd.
MRP: ₹124.6 (10 Tablets)
₹12.5/unit
Cost 127% more
Cost 127% more
View DetailsCognipride MP 2/500/15mg Tablet SR 10s
Cognitive Life Sciences Ltd.
MRP: ₹125 (10 Tablets)
₹12.5/unit
Cost 127% more
Cost 127% more
View DetailsGlimikem MP 1/500/15mg Tablet 15s
Alkem Laboratories Ltd.
MRP: ₹205 (15 Tablets)
₹13.7/unit
Cost 24% more
Cost 24% more
View DetailsUses
How Glimepiride, Metformin, and Pioglitazone Work Glimepiride, Metformin, and Pioglitazone is a combination of three antidiabetic medications: Glimepiride, Metformin, and Pioglitazone. They work through different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea that increases the amount of insulin released by the pancreas to lower blood glucose levels. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin. Pioglitazone is a thiazolidinedione that further increases insulin sensitivity.
How it Works
Common side effects of Glimepiride, Metformin, and Pioglitazone include hypoglycemia (low blood glucose level), nausea, diarrhea, headache, edema (swelling), anemia (low number of red blood cells), upper respiratory tract infection, dizziness, vomiting, flatulence, and bronchitis (inflammation of the airways).
Safety Advice
Pregnancy
Consultation Required.
Glimepiride and pioglitazone are generally avoided during pregnancy. If you are pregnant or planning to conceive, inform your doctor immediately. Alternative treatment may be necessary to ensure safe blood sugar control.
Breastfeeding
Consultation Required.
Components of this medicine may pass into breast milk; benefits for the mother must be weighed against any risks to the nursing infant. Consult your doctor before using while breastfeeding.
Alcohol
AVOID.
Alcohol can raise the risk of low blood sugar (hypoglycemia) with glimepiride or lactic acidosis with metformin, and may also worsen side effects.
Driving
Exercise Caution.
The risk of low blood sugar (hypoglycemia) may be higher if you drive, operate machinery, or combine this medicine with other diabetes medications. Know how Pioplus 1/500/15mg Tablet SR 15s affects you before engaging in such activities.
Kidney/Liver
Caution Advised.
Use requires close doctor monitoring, as metformin is usually avoided in moderate-to-severe kidney impairment and both kidney and liver function must be checked regularly. Dose adjustment or alternative medications may be needed in patients with organ dysfunction.
Is it Safe to Switch?
The Same Salt and Strenght Rule
The core of any medication is its active ingredient, or "salt." Whether you buy the original Pioplus 1/500/15mg Tablet SR 15s or a substitute, the active ingredient Glimepiride + Metformin + Pioglitazone is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.
When not to switch
While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:
Specific Allergies:You are sensitive to certain dyes or lactose fillers.
Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).
Crucial Steps Before Changing
Verify the Strength & Release Profile
Double-check your prescription for two critical details before switching brands:
Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Consult Your Physician
Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.
Myths vs. Facts About Generic Medicines
Don't let misinformation stop you from saving money. Here is the truth about generic medications.
Cheaper medicines are lower quality and take longer to work.
Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.
Generic drugs cause more side effects or stomach issues.
The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.
Generic companies skip safety testing to save money.
False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.