Substitute of Metamid Forte 5mg/850mg Tablet
Salt Composition
Glibenclamide 5mg + Metformin 850mg
Primary Use
Glibenclamide and Metformin are used in the treatment of type 2 diabetes mellitus.
Original Brand
Xemex Life Sciences
Standard Price
Syed Jommy Abbas, Pharmacist
B. Pharma
Devika Rani, MBBS
MBBS
Looking for an affordable alternative to Metamid Forte 5mg/850mg Tablet? The substitutes below contain the exact same active ingredients Glibenclamide + Metformin and offer identical therapeutic benefits.
Top Substitutes by Savings
All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Metamid Forte 5mg/850mg Tablet.
Medicine NAME
PRICE
G Formin Plus 5/850mg Tablet 10s
East West Pharma
MRP: ₹51.6 (10 Tablets)
₹5.2/unit
Cost 31% more
Cost 31% more
View DetailsUses
Glibenclamide and Metformin are used in the treatment of type 2 diabetes mellitus.
Side Effects
Common side effects of Glibenclamide and Metformin include diarrhea, nausea, flatulence, dizziness, headache, and upper respiratory tract infection.
How it Works
How Glibenclamide and Metformin Work Glibenclamide is a sulfonylurea that increases the amount of insulin released by the pancreas to lower blood glucose levels. Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and enhances the body's sensitivity to insulin.
Safety Advice
Alcohol
Caution
CONSULT YOUR DOCTOR Alcohol increases hypoglycemia risk with Glibenclamide and lactic acidosis risk with Metformin. Blood sugar control becomes unpredictable, potentially causing dangerous low sugar episodes.
Pregnancy
Caution
CONSULT YOUR DOCTOR Glibenclamide crosses placenta; Metformin category B but fetal effects unclear. Use only if diabetes control poses greater risk than medication during pregnancy.
Breastfeeding
Caution
CONSULT YOUR DOCTOR Glibenclamide passes into breast milk; Metformin levels low but may affect infant glucose. Nursing mothers should discuss alternatives or monitoring with healthcare provider.
Driving
Caution
CAUTION Hypoglycemia from Glibenclamide causes sudden dizziness, sweating, confusion. Test blood sugar before driving and carry glucose tablets for emergencies.
Liver
Caution
CONSULT YOUR DOCTOR Metformin contraindicated in severe liver disease; Glibenclamide metabolized by liver. Regular liver function tests recommended during treatment.
Kidney
Caution
CONSULT YOUR DOCTOR Metformin requires dose reduction or avoidance if eGFR <45; Glibenclamide accumulates in renal impairment. Kidney function monitoring essential.
Is it Safe to Switch?
The Same Salt and Strenght Rule
The core of any medication is its active ingredient, or "salt." Whether you buy the original Metamid Forte 5mg/850mg Tablet or a substitute, the active ingredient Glibenclamide + Metformin is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.
When not to switch
While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:
Specific Allergies:You are sensitive to certain dyes or lactose fillers.
Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).
Crucial Steps Before Changing
Verify the Strength & Release Profile
Double-check your prescription for two critical details before switching brands:
Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Consult Your Physician
Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.
Myths vs. Facts About Generic Medicines
Don't let misinformation stop you from saving money. Here is the truth about generic medications.
Cheaper medicines are lower quality and take longer to work.
Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.
Generic drugs cause more side effects or stomach issues.
The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.
Generic companies skip safety testing to save money.
False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.