Substitute of Astin LG 500/500mg Injection 1s
Salt Composition
Cilastatin 500mg + Imipenem 500mg
Primary Use
Imipenem and Cilastatin are used in the treatment of severe bacterial infections.
Original Brand
Forgo Pharmaceuticals Pvt. Ltd.
Standard Price
Looking for an affordable alternative to Astin LG 500/500mg Injection 1s? The substitutes below contain the exact same active ingredients Cilastatin + Imipenem and offer identical therapeutic benefits.
Top Substitutes by Savings
All alternatives listed below contain the exact same active ingredients and are approved for the same medical uses as Astin LG 500/500mg Injection 1s.
Medicine NAME
PRICE
Imiphrine 500/500mg Injection 2ml
Johnlee Pharmaceuticals Pvt. Ltd.
MRP: ₹1,968.8 (2 Tablets)
₹984.4/unit
Cost 323% more
Cost 323% more
View DetailsUses
Imipenem and Cilastatin are used in the treatment of severe bacterial infections.
Side Effects
Common side effects of Imipenem and Cilastatin include nausea, vomiting, diarrhea, rash, thrombophlebitis, and increased liver enzymes.
How it Works
How Imipenem and Cilastatin work Imipenem and Cilastatin is a combination of two medicines: Imipenem and Cilastatin. Imipenem is an antibiotic that works by preventing the formation of the bacterial protective covering, which is essential for the survival of bacteria in the human body. Cilastatin is a dehydropeptidase I inhibitor that blocks the activity of an enzyme (dehydropeptidase I) responsible for the breakdown of Imipenem. This action helps Imipenem remain active in your body for a longer period of time.
Is it Safe to Switch?
The Same Salt and Strenght Rule
The core of any medication is its active ingredient, or "salt." Whether you buy the original Astin LG 500/500mg Injection 1s or a substitute, the active ingredient Cilastatin + Imipenem is exactly the same. By law, generics must be bioequivalent, delivering the exact same dosage into your bloodstream at the same rate. Therapeutically, your body cannot tell the difference.
When not to switch
While the active salt is identical, inactive ingredients (binding agents, colors) vary. Consult your doctor if:
Specific Allergies:You are sensitive to certain dyes or lactose fillers.
Release Mechanisms:You are unsure if the new pill matches your prescribed release profile (IR/ER/SR).
Crucial Steps Before Changing
Verify the Strength & Release Profile
Double-check your prescription for two critical details before switching brands:
Release Speed:Pills dissolve at different rates. Check the letters on your prescription. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Exact Strength:The milligrams must match perfectly. Example: Do not swap a 50/1000mg pill for a 50/500mg pill.
Consult Your Physician
Your doctor knows your complete medical history. Don't wait weeks for an appointment just to switch brands. Consult a verified doctor online through PlatinumRx in minutes.
Myths vs. Facts About Generic Medicines
Don't let misinformation stop you from saving money. Here is the truth about generic medications.
Cheaper medicines are lower quality and take longer to work.
Generics act in the body at the exact same speed. They cost less because they do not pay for initial R&D and heavy TV marketing.
Generic drugs cause more side effects or stomach issues.
The active medicinal ingredients are 100% identical. Regulatory bodies ensure the generic's safety profile matches the original.
Generic companies skip safety testing to save money.
False. Manufacturers must pass rigorous bioequivalence testing to prove their pill behaves like the original in the human body.