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Zaleplon

Uses

Zaleplon is used in the treatment of insomnia.

How it Works

How Zaleplon works Zaleplon is a non-benzodiazepine hypnotic. In addition to its sedative effects, it may also possess anxiolytic (panic-reducing or anti-anxiety) and muscle relaxant properties. It works by binding to the GABA-A/chloride ion channel receptor complex, which relaxes the nerves and brain. This mechanism helps you fall asleep.

Side Effects

Common side effects of Zaleplon include dizziness, sleepiness, headache, abdominal pain, weakness, nausea, pain during menstruation, and eye pain.

Expert Advice

  • Your doctor has prescribed Zaleplon to help you fall asleep faster and sleep longer.
  • It is best taken without food, as a high-fat meal can reduce its absorption and effectiveness.
  • Take it 30 to 45 minutes before bedtime and only when you have time to sleep for at least 7 hours.
  • It may cause dizziness the next morning; avoid driving or engaging in activities requiring concentration until you know how it affects you.
  • Zaleplon does not affect total sleep time; however, it reduces sleep onset time and the frequency of awakenings at night.
  • Never share your medication with anyone else who has a sleep problem.
  • Inform your doctor if your sleep does not improve after 7 to 10 days of treatment.
  • Stop taking the medication and inform your doctor if you experience sleep driving or memory loss.
  • Do not stop taking the medication suddenly, as this may lead to anxiety, mood changes, and restlessness.
  • Inform your doctor if you are taking depression medication while starting treatment with Zaleplon.

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Frequently asked questions

Insomnia is a common sleep disorder characterized by difficulty falling asleep, staying asleep, or both, leading to insufficient or poor-quality sleep and a lack of refreshment upon waking.
Zaleplon should be avoided by individuals allergic to it, those with a history of depression or suicidal thoughts, individuals with a history of substance abuse, and those with kidney, liver, or lung diseases. It is also not recommended for pregnant or breastfeeding women.
No, avoid taking Zaleplon with or shortly after a high-fat meal, as it may reduce the medication's effectiveness.
Insomnia can be primary (unknown cause) or secondary (due to factors like stress, medical conditions, medications, or stimulants such as caffeine and nicotine).
Yes, Zaleplon has abuse potential, particularly in individuals with a history of drug or alcohol abuse. Physicians should assess the patient's history of substance use and monitor those at risk closely during treatment.
Avoid driving or operating heavy machinery until you know how Zaleplon affects you. Additionally, do not consume alcohol while taking Zaleplon, as it can exacerbate side effects.
Enhance your sleep by avoiding caffeine and nicotine late in the day, refraining from late exercise, avoiding large evening meals, not napping, maintaining a consistent sleep schedule, keeping your bedroom dark and comfortable, and practicing relaxation techniques before bed.
Zaleplon begins to work immediately, making you very sleepy. Plan to go to bed right after taking it and ensure you can stay in bed for 7 to 8 hours.
Do not discontinue Zaleplon without consulting your doctor. Sudden cessation may lead to withdrawal symptoms like discomfort, stomach cramps, vomiting, sweating, shakiness, and, in rare cases, seizures.
Yes, dry mouth is a common side effect of Zaleplon, while weight gain is less common and may be linked to increased appetite.
Symptoms of Zaleplon overdose include drowsiness, confusion, coordination issues, muscle weakness, slow or difficult breathing, and potentially coma.
Zaleplon is intended for short-term use (2-4 weeks) for insomnia and should be taken exactly as prescribed to avoid dependence.
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