Verteporfin

Uses

Verteporfin is used in the treatment of wet age-related macular degeneration.

How it Works

How Verteporfin works: Verteporfin accumulates in abnormal blood vessels and, when stimulated by non-thermal red light in the presence of oxygen, produces highly reactive, short-lived singlet oxygen and other reactive oxygen radicals. This process results in local damage to the endothelium and blockage of the vessels.

Side Effects

Common side effects of Verteporfin include eye itching, cataract, high blood pressure, injection site reaction, visual disturbance, conjunctivitis, eyelid inflammation, decreased vision, photosensitivity, weakness, fever, flu-like symptoms, eczema, gastrointestinal cancer, constipation, anemia (low number of red blood cells), abnormal liver function tests, albumin in urine, joint pain, sleep disorder, cough, double vision, hearing impairment, and benign prostatic hyperplasia.

Expert Advice

Verteporfin is used for the treatment of eye diseases caused by:

Diabetes
Macular degeneration
Macular swelling

It is administered directly into the eyeball by an eye specialist.
It may cause temporary visual disturbances.
Do not drive or engage in activities requiring mental focus until you understand how Verteporfin affects you.
Inform your doctor if you experience: