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Trioxasalen

Uses

Trioxasalen is used in the treatment of vitiligo and psoriasis.

How it Works

How Trioxasalen works Trioxasalen is a photosensitive medication used in conjunction with UV-A rays. It functions by activating specific skin cells (melanocytes) and aids in repigmenting the discolored white patches associated with vitiligo. Additionally, Trioxasalen slows the rapid growth of skin cells in psoriasis, which helps reduce scaling and thickening of the skin.

Side Effects

Common side effects of Trioxasalen include erythema (skin redness), blisters on the skin, edema (swelling), and itching.

Expert Advice

  • Trioxsalen is a potent medication that enhances your skin's sensitivity to sunlight.
  • Do not use it for sun tanning or to increase sunlight tolerance; if used for these purposes, limit use to a maximum of 14 days.
  • Administer this treatment (trioxsalen and UVA) two or three times a week, ensuring treatments are spaced at least 48 hours apart.
  • Take this medication orally with food or milk, usually 2 to 4 hours prior to your UVA light treatment.
  • Avoid sunbathing for 24 hours before taking trioxsalen.
  • Wear UVA-absorbing, wrap-around sunglasses and cover exposed skin or apply a sunblock (SPF 15 or higher) for the 24-hour period following treatment with trioxsalen.
  • Exercise extra caution for at least 48 hours after each treatment.
  • After each treatment, protect your skin for a minimum of 8 hours by wearing appropriate clothing.
  • Do not increase the dosage of trioxsalen if you are spending additional time in sunlight or under an ultraviolet lamp.
  • Avoid driving or operating machinery, as trioxsalen may cause dizziness.
  • You will need to undergo an eye examination before starting trioxsalen and annually thereafter.
  • Be cautious when applying anything to your skin to alleviate dryness and itchiness caused by trioxsalen.
  • Inform your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

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